Gene name: BRR6
Reference locus (S288C): YGL247W
Gene biotype: protein_coding
Description: Nucleus export protein BRR6; Essential nuclear envelope integral membrane protein; interacts and functions with Apq12p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA nuclear export, and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism; homologous to Brl1p; Belongs to the BRL1/BRR6 family
Top 10 interactors (score): APQ12 (0.948); YOP1 (0.861); NUP188 (0.838); POM33 (0.822); POM152 (0.78); NUP133 (0.778); SPO7 (0.771); BRL1 (0.763); RTN1 (0.72); ROT1 (0.719); NUP157 (0.711); NUP53 (0.694); SRM1 (0.694); GLE2 (0.694); POM34 (0.692); NUP159 (0.69); ACC1 (0.664); NUP120 (0.651); ASM4 (0.651); CHM7 (0.574)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:38458-39051:+ | gene-YGL247W_AKU4011 | rna-NM_001181113.1_AKU4011 | cds-NP_011267.1_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:30497-31090:+ | gene-YGL247W_BG1 | rna-NM_001181113.1_BG1 | cds-NP_011267.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:38813-39406:+ | gene-YGL247W_Bruggeman | rna-NM_001181113.1_Bruggeman | cds-NP_011267.1_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:36885-37478:+ | gene-YGL247W_CAT1 | rna-NM_001181113.1_CAT1 | cds-NP_011267.1_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:42746-43339:+ | gene-YGL247W_CBS1585 | rna-NM_001181113.1_CBS1585 | cds-NP_011267.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:37474-38067:+ | gene-YGL247W_CBS436 | rna-NM_001181113.1_CBS436 | cds-NP_011267.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:30314-30907:+ | gene-YGL247W_CBS6412 | rna-NM_001181113.1_CBS6412 | cds-NP_011267.1_CBS6412 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:36602-37195:+ | gene-YGL247W_CBS6413 | rna-NM_001181113.1_CBS6413 | cds-NP_011267.1_CBS6413 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:36595-37188:+ | gene-YGL247W_CENPK1137D | rna-NM_001181113.1_CENPK1137D | cds-NP_011267.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:29735-30328:+ | gene-YGL247W_EthanolRed | rna-NM_001181113.1_EthanolRed | cds-NP_011267.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:30096-30689:+ | gene-YGL247W_FaliES1 | rna-NM_001181113.1_FaliES1 | cds-NP_011267.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:36392-36985:- | gene-YGL247W_JAY291 | rna-NM_001181113.1_JAY291 | cds-NP_011267.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:38750-39343:+ | gene-YGL247W_MUCL30387 | rna-NM_001181113.1_MUCL30387 | cds-NP_011267.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:40903-41496:+ | gene-YGL247W_MUCL30388 | rna-NM_001181113.1_MUCL30388 | cds-NP_011267.1_MUCL30388 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:39343-39936:+ | gene-YGL247W_MUCL39482 | rna-NM_001181113.1_MUCL39482 | cds-NP_011267.1_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:42236-42829:+ | gene-YGL247W_MUCL42920 | rna-NM_001181113.1_MUCL42920 | cds-NP_011267.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:36933-37526:+ | gene-YGL247W_NCIM3186 | rna-NM_001181113.1_NCIM3186 | cds-NP_011267.1_NCIM3186 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:31107-31700:+ | gene-YGL247W_NCYC1407 | rna-NM_001181113.1_NCYC1407 | cds-NP_011267.1_NCYC1407 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:32963-33556:+ | gene-YGL247W_PE2H3 | rna-NM_001181113.1_PE2H3 | cds-NP_011267.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:32511-33104:+ | gene-YGL247W_PE2H4 | rna-NM_001181113.1_PE2H4 | cds-NP_011267.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:36933-37526:+ | gene-YGL247W_S288C | rna-NM_001181113.1_S288C | cds-NP_011267.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:337808-338401:- | gene-YGL247W_SA1 | rna-NM_001181113.1_SA1 | cds-NP_011267.1_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:30411-31004:+ | gene-YGL247W_ThermosaccDry | rna-NM_001181113.1_ThermosaccDry | cds-NP_011267.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:37400-37993:+ | gene-YGL247W_VR1 | rna-NM_001181113.1_VR1 | cds-NP_011267.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:29484-30077:+ | gene-YGL247W_ZTW1 | rna-NM_001181113.1_ZTW1 | cds-NP_011267.1_ZTW1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:38174-38767:+ | gene-YGL247W_Sparadoxus | rna-NM_001181113.1_Sparadoxus | cds-NP_011267.1_Sparadoxus | 86.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |