BRR2 (YER172C)


Gene profile

Gene name: BRR2
Reference locus (S288C): YER172C
Gene biotype: protein_coding

Description: Pre-mRNA-splicing helicase BRR2; RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD

Top 10 interactors (score): SYF2 (0.999); AAR2 (0.999); SNU23 (0.999); LEA1 (0.999); SMX3 (0.999); CWC2 (0.999); SMX2 (0.999); SNU114 (0.999); RSE1 (0.999); HUB1 (0.999); PRP19 (0.999); LSM8 (0.999); SMB1 (0.999); CDC40 (0.999); LSM5 (0.999); PRP9 (0.999); PRP38 (0.999); CUS1 (0.999); PRP8 (0.999); LSM2 (0.999)

Homologues (species, bitscore): SNRNP200 (Homo sapiens, 1538.1); Snrnp200 (Mus musculus, 1538.9); snrnp200 (Danio rerio, 1530.0); snrnp200 (Xenopus tropicalis, 1534.6); l(3)72Ab (Drosophila melanogaster, 1530.4); snrp-200 (Caenorhabditis elegans, 1411.0); emb1507 (Arabidopsis thaliana, 1508.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:511052-517543:- gene-YER172C_AKU4011 rna-NM_001179062.1_AKU4011 cds-NP_011099.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000176.1:15824-22312:+ gene-YER172C_BG1 rna-NM_001179062.1_BG1 cds-NP_011099.1_BG1 99.5 99.9 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:523794-530285:- gene-YER172C_Bruggeman rna-NM_001179062.1_Bruggeman cds-NP_011099.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:510386-516874:- gene-YER172C_CAT1 rna-NM_001179062.1_CAT1 cds-NP_011099.1_CAT1 99.5 99.9 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:510859-517350:- gene-YER172C_CBS1585 rna-NM_001179062.1_CBS1585 cds-NP_011099.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:520754-527242:- gene-YER172C_CBS436 rna-NM_001179062.1_CBS436 cds-NP_011099.1_CBS436 99.5 99.9 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:508836-515327:- gene-YER172C_CBS6412 rna-NM_001179062.1_CBS6412 cds-NP_011099.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:517405-523896:- gene-YER172C_CBS6413 rna-NM_001179062.1_CBS6413 cds-NP_011099.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:527299-533790:- gene-YER172C_CENPK1137D rna-NM_001179062.1_CENPK1137D cds-NP_011099.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:517026-523517:- gene-YER172C_EthanolRed rna-NM_001179062.1_EthanolRed cds-NP_011099.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:517962-524453:- gene-YER172C_FaliES1 rna-NM_001179062.1_FaliES1 cds-NP_011099.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000169.1:15453-21944:+ gene-YER172C_JAY291 rna-NM_001179062.1_JAY291 cds-NP_011099.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:511111-517599:- gene-YER172C_MUCL30387 rna-NM_001179062.1_MUCL30387 cds-NP_011099.1_MUCL30387 99.6 99.9 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:514027-520515:- gene-YER172C_MUCL30388 rna-NM_001179062.1_MUCL30388 cds-NP_011099.1_MUCL30388 99.6 99.9 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:506817-513308:- gene-YER172C_MUCL39482 rna-NM_001179062.1_MUCL39482 cds-NP_011099.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:521343-527831:- gene-YER172C_MUCL42920 rna-NM_001179062.1_MUCL42920 cds-NP_011099.1_MUCL42920 99.6 99.9 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:529529-536020:- gene-YER172C_NCIM3186 rna-NM_001179062.1_NCIM3186 cds-NP_011099.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:516272-522763:- gene-YER172C_NCYC1407 rna-NM_001179062.1_NCYC1407 cds-NP_011099.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:532205-538696:- gene-YER172C_PE2H3 rna-NM_001179062.1_PE2H3 cds-NP_011099.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:522146-528637:- gene-YER172C_PE2H4 rna-NM_001179062.1_PE2H4 cds-NP_011099.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:529530-536021:- gene-YER172C_S288C rna-NM_001179062.1_S288C cds-NP_011099.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000030.1:81683-88174:- gene-YER172C_SA1 rna-NM_001179062.1_SA1 cds-NP_011099.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:518762-525253:- gene-YER172C_ThermosaccDry rna-NM_001179062.1_ThermosaccDry cds-NP_011099.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:512051-518539:- gene-YER172C_VR1 rna-NM_001179062.1_VR1 cds-NP_011099.1_VR1 99.4 99.9 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000011.1:31609-38100:- gene-YER172C_ZTW1 rna-NM_001179062.1_ZTW1 cds-NP_011099.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:519989-526483:- gene-YER172C_Sparadoxus rna-NM_001179062.1_Sparadoxus cds-NP_011099.1_Sparadoxus 89.0 99.9 Verified 1 1 1 False True False False False

Additional files