Gene name: BRO1
Reference locus (S288C): YPL084W
Gene biotype: protein_coding
Description: Vacuolar-sorting protein BRO1; Cytoplasmic class E vacuolar protein sorting (VPS) factor; coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes
Top 10 interactors (score): SNF7 (0.999); DOA4 (0.998); VPS4 (0.992); VPS20 (0.986); STP22 (0.985); RFU1 (0.975); VPS24 (0.974); HSE1 (0.963); VPS27 (0.962); VPS36 (0.954); DID4 (0.946); VPS28 (0.938); RIM101 (0.93); RSP5 (0.927); PEF1 (0.918); SNF8 (0.914); DID2 (0.911); VPS25 (0.907); IST1 (0.903); MVB12 (0.848)
Homologues (species, bitscore): PDCD6IP (Homo sapiens, 143.7); Pdcd6ip (Mus musculus, 141.4); ptpn23b (Danio rerio, 141.7); pdcd6ip (Xenopus tropicalis, 129.0); mop (Drosophila melanogaster, 117.5); alx-1 (Caenorhabditis elegans, 94.4); AT1G15130 (Arabidopsis thaliana, 83.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:371775-374309:+ | gene-YPL084W_AKU4011 | rna-NM_001183898.1_AKU4011 | cds-NP_015241.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:577461-579995:+ | gene-YPL084W_BG1 | rna-NM_001183898.1_BG1 | cds-NP_015241.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:448098-450632:+ | gene-YPL084W_Bruggeman | rna-NM_001183898.1_Bruggeman | cds-NP_015241.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:488446-490980:+ | gene-YPL084W_CAT1 | rna-NM_001183898.1_CAT1 | cds-NP_015241.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:375842-378376:+ | gene-YPL084W_CBS1585 | rna-NM_001183898.1_CBS1585 | cds-NP_015241.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:390397-392931:+ | gene-YPL084W_CBS436 | rna-NM_001183898.1_CBS436 | cds-NP_015241.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:380036-382570:+ | gene-YPL084W_CBS6412 | rna-NM_001183898.1_CBS6412 | cds-NP_015241.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:372390-374924:+ | gene-YPL084W_CBS6413 | rna-NM_001183898.1_CBS6413 | cds-NP_015241.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:394010-396544:+ | gene-YPL084W_CENPK1137D | rna-NM_001183898.1_CENPK1137D | cds-NP_015241.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:370142-372676:+ | gene-YPL084W_EthanolRed | rna-NM_001183898.1_EthanolRed | cds-NP_015241.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:377972-380506:+ | gene-YPL084W_FaliES1 | rna-NM_001183898.1_FaliES1 | cds-NP_015241.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000350.1:10733-13267:- | gene-YPL084W_JAY291 | rna-NM_001183898.1_JAY291 | cds-NP_015241.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:388927-391461:+ | gene-YPL084W_MUCL30387 | rna-NM_001183898.1_MUCL30387 | cds-NP_015241.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:387730-390264:+ | gene-YPL084W_MUCL30388 | rna-NM_001183898.1_MUCL30388 | cds-NP_015241.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:369171-371705:+ | gene-YPL084W_MUCL39482 | rna-NM_001183898.1_MUCL39482 | cds-NP_015241.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:427036-429570:+ | gene-YPL084W_MUCL42920 | rna-NM_001183898.1_MUCL42920 | cds-NP_015241.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:394021-396555:+ | gene-YPL084W_NCIM3186 | rna-NM_001183898.1_NCIM3186 | cds-NP_015241.1_NCIM3186 | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:375782-378316:+ | gene-YPL084W_NCYC1407 | rna-NM_001183898.1_NCYC1407 | cds-NP_015241.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:383056-385590:+ | gene-YPL084W_PE2H3 | rna-NM_001183898.1_PE2H3 | cds-NP_015241.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:382679-385213:+ | gene-YPL084W_PE2H4 | rna-NM_001183898.1_PE2H4 | cds-NP_015241.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:394038-396572:+ | gene-YPL084W_S288C | rna-NM_001183898.1_S288C | cds-NP_015241.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000057.1:16154-18688:+ | gene-YPL084W_SA1 | rna-NM_001183898.1_SA1 | cds-NP_015241.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:377772-380306:+ | gene-YPL084W_ThermosaccDry | rna-NM_001183898.1_ThermosaccDry | cds-NP_015241.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:392765-395299:+ | gene-YPL084W_VR1 | rna-NM_001183898.1_VR1 | cds-NP_015241.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:377079-379613:+ | gene-YPL084W_ZTW1 | rna-NM_001183898.1_ZTW1 | cds-NP_015241.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:378696-381227:+ | gene-YPL084W_Sparadoxus | rna-NM_001183898.1_Sparadoxus | cds-NP_015241.1_Sparadoxus | 88.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |