BRL1 (YHR036W)


Gene profile

Gene name: BRL1
Reference locus (S288C): YHR036W
Gene biotype: protein_coding

Description: Nucleus export protein BRL1; Essential nuclear envelope/ER integral membrane protein; interacts and functions with Apq12p and Brr6p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, mRNA nuclear export and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; identified as a dosage suppressor of a temperature sensitive mutation in the major karyopherin, CRM1; homologous to Brr6p; Belongs to the BRL1/BRR6 family

Top 10 interactors (score): SRM1 (0.779); CRM1 (0.772); BRR6 (0.763); SPT15 (0.499); BRF1 (0.495); GLE2 (0.428); MNN11 (0.416); NUP116 (0.408)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:168615-170030:+ gene-YHR036W_AKU4011 rna-NM_001179166.1_AKU4011 cds-NP_011901.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:88820-90235:+ gene-YHR036W_BG1 rna-NM_001179166.1_BG1 cds-NP_011901.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:176054-177469:+ gene-YHR036W_Bruggeman rna-NM_001179166.1_Bruggeman cds-NP_011901.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:170439-171854:+ gene-YHR036W_CAT1 rna-NM_001179166.1_CAT1 cds-NP_011901.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:168987-170402:+ gene-YHR036W_CBS1585 rna-NM_001179166.1_CBS1585 cds-NP_011901.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:163222-164637:+ gene-YHR036W_CBS436 rna-NM_001179166.1_CBS436 cds-NP_011901.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:167949-169364:+ gene-YHR036W_CBS6412 rna-NM_001179166.1_CBS6412 cds-NP_011901.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:168794-170209:+ gene-YHR036W_CBS6413 rna-NM_001179166.1_CBS6413 cds-NP_011901.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:173606-175021:+ gene-YHR036W_CENPK1137D rna-NM_001179166.1_CENPK1137D cds-NP_011901.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:168119-169534:+ gene-YHR036W_EthanolRed rna-NM_001179166.1_EthanolRed cds-NP_011901.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:169098-170513:+ gene-YHR036W_FaliES1 rna-NM_001179166.1_FaliES1 cds-NP_011901.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000273.1:11135-12550:- gene-YHR036W_JAY291 rna-NM_001179166.1_JAY291 cds-NP_011901.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:175123-176538:+ gene-YHR036W_MUCL30387 rna-NM_001179166.1_MUCL30387 cds-NP_011901.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:175593-177008:+ gene-YHR036W_MUCL30388 rna-NM_001179166.1_MUCL30388 cds-NP_011901.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:168024-169439:+ gene-YHR036W_MUCL39482 rna-NM_001179166.1_MUCL39482 cds-NP_011901.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:174683-176098:+ gene-YHR036W_MUCL42920 rna-NM_001179166.1_MUCL42920 cds-NP_011901.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:180227-181642:+ gene-YHR036W_NCIM3186 rna-NM_001179166.1_NCIM3186 cds-NP_011901.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:167887-169302:+ gene-YHR036W_NCYC1407 rna-NM_001179166.1_NCYC1407 cds-NP_011901.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:170217-171632:+ gene-YHR036W_PE2H3 rna-NM_001179166.1_PE2H3 cds-NP_011901.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:177658-179073:+ gene-YHR036W_PE2H4 rna-NM_001179166.1_PE2H4 cds-NP_011901.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:180345-181760:+ gene-YHR036W_S288C rna-NM_001179166.1_S288C cds-NP_011901.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:176810-178225:- gene-YHR036W_SA1 rna-NM_001179166.1_SA1 cds-NP_011901.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:170187-171602:+ gene-YHR036W_ThermosaccDry rna-NM_001179166.1_ThermosaccDry cds-NP_011901.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:176708-178123:+ gene-YHR036W_VR1 rna-NM_001179166.1_VR1 cds-NP_011901.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:161738-163153:+ gene-YHR036W_ZTW1 rna-NM_001179166.1_ZTW1 cds-NP_011901.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:167809-169224:+ gene-YHR036W_Sparadoxus rna-NM_001179166.1_Sparadoxus cds-NP_011901.1_Sparadoxus 90.3 99.7 Verified 1 1 1 False True False False False

Additional files