Gene name: BRF1
Reference locus (S288C): YGR246C
Gene biotype: protein_coding
Description: TFIIIB B-related factor; one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB; mutations in human homolog are associated with autosomal recessive cerebellar-facial-dental syndrome; Belongs to the TFIIB family
Top 10 interactors (score): TFC4 (0.999); BDP1 (0.999); SPT15 (0.999); TFC1 (0.998); RPC34 (0.998); RPO31 (0.994); RET1 (0.993); TFC8 (0.99); RPC53 (0.988); TFC3 (0.987); RPB5 (0.987); RPC19 (0.987); RPO26 (0.984); RPC82 (0.982); RPC17 (0.98); RPC31 (0.98); RPB8 (0.978); RPC37 (0.978); RPC10 (0.977); TFC6 (0.975)
Homologues (species, bitscore): BRF1 (Homo sapiens, 278.1); Brf1 (Mus musculus, 270.0); brf1a (Danio rerio, 281.6); brf1 (Xenopus tropicalis, 260.4); Brf (Drosophila melanogaster, 255.0); brf-1 (Caenorhabditis elegans, 235.7); AT3G09360 (Arabidopsis thaliana, 173.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:947904-949694:- | gene-YGR246C_AKU4011 | rna-NM_001181375.1_AKU4011 | cds-NP_011762.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:228004-229794:- | gene-YGR246C_BG1 | rna-NM_001181375.1_BG1 | cds-NP_011762.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:955500-957290:- | gene-YGR246C_Bruggeman | rna-NM_001181375.1_Bruggeman | cds-NP_011762.1_Bruggeman | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:955014-956804:- | gene-YGR246C_CAT1 | rna-NM_001181375.1_CAT1 | cds-NP_011762.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:950760-952550:- | gene-YGR246C_CBS1585 | rna-NM_001181375.1_CBS1585 | cds-NP_011762.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:954405-956195:- | gene-YGR246C_CBS436 | rna-NM_001181375.1_CBS436 | cds-NP_011762.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:941642-943432:- | gene-YGR246C_CBS6412 | rna-NM_001181375.1_CBS6412 | cds-NP_011762.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:947695-949485:- | gene-YGR246C_CBS6413 | rna-NM_001181375.1_CBS6413 | cds-NP_011762.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:982163-983953:- | gene-YGR246C_CENPK1137D | rna-NM_001181375.1_CENPK1137D | cds-NP_011762.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:935734-937524:- | gene-YGR246C_EthanolRed | rna-NM_001181375.1_EthanolRed | cds-NP_011762.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:940541-942331:- | gene-YGR246C_FaliES1 | rna-NM_001181375.1_FaliES1 | cds-NP_011762.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:87969-89759:+ | gene-YGR246C_JAY291 | rna-NM_001181375.1_JAY291 | cds-NP_011762.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:953415-955205:- | gene-YGR246C_MUCL30387 | rna-NM_001181375.1_MUCL30387 | cds-NP_011762.1_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:952681-954471:- | gene-YGR246C_MUCL30388 | rna-NM_001181375.1_MUCL30388 | cds-NP_011762.1_MUCL30388 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:945885-947675:- | gene-YGR246C_MUCL39482 | rna-NM_001181375.1_MUCL39482 | cds-NP_011762.1_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:964393-966183:- | gene-YGR246C_MUCL42920 | rna-NM_001181375.1_MUCL42920 | cds-NP_011762.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:982482-984272:- | gene-YGR246C_NCIM3186 | rna-NM_001181375.1_NCIM3186 | cds-NP_011762.1_NCIM3186 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:941504-943294:- | gene-YGR246C_NCYC1407 | rna-NM_001181375.1_NCYC1407 | cds-NP_011762.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:966678-968468:- | gene-YGR246C_PE2H3 | rna-NM_001181375.1_PE2H3 | cds-NP_011762.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:971517-973307:- | gene-YGR246C_PE2H4 | rna-NM_001181375.1_PE2H4 | cds-NP_011762.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:982482-984272:- | gene-YGR246C_S288C | rna-NM_001181375.1_S288C | cds-NP_011762.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:17214-19004:+ | gene-YGR246C_SA1 | rna-NM_001181375.1_SA1 | cds-NP_011762.1_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:961068-962858:- | gene-YGR246C_ThermosaccDry | rna-NM_001181375.1_ThermosaccDry | cds-NP_011762.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1066328-1068118:- | gene-YGR246C_VR1 | rna-NM_001181375.1_VR1 | cds-NP_011762.1_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:262472-264261:- | gene-YGR246C_ZTW1 | rna-NM_001181375.1_ZTW1 | cds-NP_011762.1_ZTW1 | 98.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:953271-955052:- | gene-YGR246C_Sparadoxus | rna-NM_001181375.1_Sparadoxus | cds-NP_011762.1_Sparadoxus | 88.5 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |