Gene name: BOL3
Reference locus (S288C): YAL046C
Gene biotype: protein_coding
Description: BolA-like protein 3; Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress by acting along with Nfu1p at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to mitochondrial client proteins like lipoate synthase and succinate dehydrogenase; sequence similarity to human BOLA family member, BOLA3, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS2)
Top 10 interactors (score): GRX5 (0.999); BOL1 (0.998); NFU1 (0.987); LIP5 (0.976); DRE2 (0.975); BOL2 (0.974); IBA57 (0.965); GRX3 (0.964); ISA2 (0.961); GRX4 (0.939); ISA1 (0.905); MGE1 (0.891); JAC1 (0.835); BIO2 (0.828); ISD11 (0.822); YAH1 (0.807); ISU1 (0.803); TAH18 (0.792); AIM2 (0.747); ATM1 (0.746)
Homologues (species, bitscore): BOLA3 (Homo sapiens, 60.8); Bola3 (Mus musculus, 60.8); BOLA3 (Danio rerio, 64.7); bola3 (Xenopus tropicalis, 57.0); CG33672 (Drosophila melanogaster, 54.7); Y105E8A.11 (Caenorhabditis elegans, 55.1); AT5G09830 (Arabidopsis thaliana, 53.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:42174-42530:- | gene-YAL046C_AKU4011 | rna-NM_001178191.1_AKU4011 | cds-NP_009353.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:29243-29599:- | gene-YAL046C_BG1 | rna-NM_001178191.1_BG1 | cds-NP_009353.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:56632-56988:- | gene-YAL046C_Bruggeman | rna-NM_001178191.1_Bruggeman | cds-NP_009353.1_Bruggeman | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:43392-43748:- | gene-YAL046C_CAT1 | rna-NM_001178191.1_CAT1 | cds-NP_009353.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:55195-55551:- | gene-YAL046C_CBS1585 | rna-NM_001178191.1_CBS1585 | cds-NP_009353.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:55438-55794:- | gene-YAL046C_CBS436 | rna-NM_001178191.1_CBS436 | cds-NP_009353.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:41340-41696:- | gene-YAL046C_CBS6412 | rna-NM_001178191.1_CBS6412 | cds-NP_009353.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:53458-53814:- | gene-YAL046C_CBS6413 | rna-NM_001178191.1_CBS6413 | cds-NP_009353.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:57085-57441:- | gene-YAL046C_CENPK1137D | rna-NM_001178191.1_CENPK1137D | cds-NP_009353.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:43588-43944:- | gene-YAL046C_EthanolRed | rna-NM_001178191.1_EthanolRed | cds-NP_009353.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:57530-57886:- | gene-YAL046C_FaliES1 | rna-NM_001178191.1_FaliES1 | cds-NP_009353.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:29482-29838:- | gene-YAL046C_JAY291 | rna-NM_001178191.1_JAY291 | cds-NP_009353.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:58136-58492:- | gene-YAL046C_MUCL30387 | rna-NM_001178191.1_MUCL30387 | cds-NP_009353.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:54683-55039:- | gene-YAL046C_MUCL30388 | rna-NM_001178191.1_MUCL30388 | cds-NP_009353.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:53999-54355:- | gene-YAL046C_MUCL39482 | rna-NM_001178191.1_MUCL39482 | cds-NP_009353.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:56341-56697:- | gene-YAL046C_MUCL42920 | rna-NM_001178191.1_MUCL42920 | cds-NP_009353.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:56906-57262:- | gene-YAL046C_NCIM3186 | rna-NM_001178191.1_NCIM3186 | cds-NP_009353.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:41864-42220:- | gene-YAL046C_NCYC1407 | rna-NM_001178191.1_NCYC1407 | cds-NP_009353.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:43746-44102:- | gene-YAL046C_PE2H3 | rna-NM_001178191.1_PE2H3 | cds-NP_009353.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:43465-43821:- | gene-YAL046C_PE2H4 | rna-NM_001178191.1_PE2H4 | cds-NP_009353.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:57029-57385:- | gene-YAL046C_S288C | rna-NM_001178191.1_S288C | cds-NP_009353.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000084.1:31639-31995:- | gene-YAL046C_SA1 | rna-NM_001178191.1_SA1 | cds-NP_009353.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:57740-58096:- | gene-YAL046C_ThermosaccDry | rna-NM_001178191.1_ThermosaccDry | cds-NP_009353.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:59005-59361:- | gene-YAL046C_VR1 | rna-NM_001178191.1_VR1 | cds-NP_009353.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:29549-29905:- | gene-YAL046C_ZTW1 | rna-NM_001178191.1_ZTW1 | cds-NP_009353.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:47245-47601:- | gene-YAL046C_Sparadoxus | rna-NM_001178191.1_Sparadoxus | cds-NP_009353.1_Sparadoxus | 92.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |