Gene name: BOL2
Reference locus (S288C): YGL220W
Gene biotype: protein_coding
Description: BolA-like protein 2; Cytosolic protein involved in repression of iron regulon transcription; forms an iron-independent complex with Fra1p, Grx3p, and Grx4p; null mutant fails to repress the iron regulon and is sensitive to nickel; sequence similarity to human BOLA family member, BOLA2; Belongs to the BolA/IbaG family
Top 10 interactors (score): GRX3 (0.999); GRX4 (0.999); BOL1 (0.985); DRE2 (0.984); FRA1 (0.982); BOL3 (0.974); GRX5 (0.969); AFT2 (0.942); NFU1 (0.889); AFT1 (0.861); FET3 (0.834); ISA2 (0.799); ISA1 (0.792); MGE1 (0.79); ISU1 (0.762); IBA57 (0.761); SUA5 (0.747); YDL009C (0.744); YDL057W (0.744); LIP5 (0.732)
Homologues (species, bitscore): BOLA2B (Homo sapiens, 55.8); Bola2 (Mus musculus, 59.3); BOLA2B (Danio rerio, 61.6); bola2 (Xenopus tropicalis, 60.5); CG33672 (Drosophila melanogaster, 73.2); AT5G09830 (Arabidopsis thaliana, 65.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:83716-84078:+ | gene-YGL220W_AKU4011 | rna-NM_001181085.1_AKU4011 | cds-NP_011295.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:76779-77141:+ | gene-YGL220W_BG1 | rna-NM_001181085.1_BG1 | cds-NP_011295.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:84226-84588:+ | gene-YGL220W_Bruggeman | rna-NM_001181085.1_Bruggeman | cds-NP_011295.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:82889-83251:+ | gene-YGL220W_CAT1 | rna-NM_001181085.1_CAT1 | cds-NP_011295.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:88021-88383:+ | gene-YGL220W_CBS1585 | rna-NM_001181085.1_CBS1585 | cds-NP_011295.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:83583-83945:+ | gene-YGL220W_CBS436 | rna-NM_001181085.1_CBS436 | cds-NP_011295.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:75152-75514:+ | gene-YGL220W_CBS6412 | rna-NM_001181085.1_CBS6412 | cds-NP_011295.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:81856-82218:+ | gene-YGL220W_CBS6413 | rna-NM_001181085.1_CBS6413 | cds-NP_011295.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:82408-82770:+ | gene-YGL220W_CENPK1137D | rna-NM_001181085.1_CENPK1137D | cds-NP_011295.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:74518-74880:+ | gene-YGL220W_EthanolRed | rna-NM_001181085.1_EthanolRed | cds-NP_011295.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:75361-75723:+ | gene-YGL220W_FaliES1 | rna-NM_001181085.1_FaliES1 | cds-NP_011295.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:1765-2127:+ | gene-YGL220W_JAY291 | rna-NM_001181085.1_JAY291 | cds-NP_011295.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:84142-84504:+ | gene-YGL220W_MUCL30387 | rna-NM_001181085.1_MUCL30387 | cds-NP_011295.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:86321-86683:+ | gene-YGL220W_MUCL30388 | rna-NM_001181085.1_MUCL30388 | cds-NP_011295.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:84534-84896:+ | gene-YGL220W_MUCL39482 | rna-NM_001181085.1_MUCL39482 | cds-NP_011295.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:87640-88002:+ | gene-YGL220W_MUCL42920 | rna-NM_001181085.1_MUCL42920 | cds-NP_011295.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:82374-82736:+ | gene-YGL220W_NCIM3186 | rna-NM_001181085.1_NCIM3186 | cds-NP_011295.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:76253-76615:+ | gene-YGL220W_NCYC1407 | rna-NM_001181085.1_NCYC1407 | cds-NP_011295.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:79082-79444:+ | gene-YGL220W_PE2H3 | rna-NM_001181085.1_PE2H3 | cds-NP_011295.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:78630-78992:+ | gene-YGL220W_PE2H4 | rna-NM_001181085.1_PE2H4 | cds-NP_011295.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:82374-82736:+ | gene-YGL220W_S288C | rna-NM_001181085.1_S288C | cds-NP_011295.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:292551-292913:- | gene-YGL220W_SA1 | rna-NM_001181085.1_SA1 | cds-NP_011295.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:75622-75984:+ | gene-YGL220W_ThermosaccDry | rna-NM_001181085.1_ThermosaccDry | cds-NP_011295.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:83495-83857:+ | gene-YGL220W_VR1 | rna-NM_001181085.1_VR1 | cds-NP_011295.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:74671-75033:+ | gene-YGL220W_ZTW1 | rna-NM_001181085.1_ZTW1 | cds-NP_011295.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:81725-82087:+ | gene-YGL220W_Sparadoxus | rna-NM_001181085.1_Sparadoxus | cds-NP_011295.1_Sparadoxus | 89.6 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |