Gene name: BOL1
Reference locus (S288C): YAL044W-A
Gene biotype: protein_coding
Description: BolA-like protein 1; Mitochondrial matrix protein involved in Fe-S cluster biogenesis; facilitates [4Fe-2S] cluster inception into mitochondrial proteins such as lipoate synthase and succinate dehydrogenase; interacts and may function with Grx5p at an early step in Fe-S cluster biosynthesis; forms dimeric complexes with Grx5p and Nfu1p that alter the stability of shared Fe/S clusters; sequence similarity to human BOLA family member, BOLA1 and S. pombe uvi31, a putative DNA repair protein
Top 10 interactors (score): GRX5 (0.999); BOL3 (0.998); DRE2 (0.992); GRX3 (0.986); BOL2 (0.985); GRX4 (0.98); NFU1 (0.972); LIP5 (0.97); IBA57 (0.917); ISA2 (0.902); ISA1 (0.888); YAH1 (0.861); JAC1 (0.842); ISU1 (0.812); MET18 (0.775); OXA1 (0.762); YDL009C (0.748); YDL057W (0.748); NFS1 (0.745); BIO2 (0.74)
Homologues (species, bitscore): BOLA1 (Homo sapiens, 56.6); Bola1 (Mus musculus, 61.2); bola1 (Danio rerio, 62.4); BOLA1 (Xenopus tropicalis, 57.8); K11H12.1 (Caenorhabditis elegans, 52.4); AT1G55805 (Arabidopsis thaliana, 76.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005295.1:42663-42995:+ | gene-YAL044W-A_AKU4011 | rna-NM_001184453.1_AKU4011 | cds-NP_075206.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000070.1:29732-30064:+ | gene-YAL044W-A_BG1 | rna-NM_001184453.1_BG1 | cds-NP_075206.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005503.1:57121-57453:+ | gene-YAL044W-A_Bruggeman | rna-NM_001184453.1_Bruggeman | cds-NP_075206.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005519.1:43881-44213:+ | gene-YAL044W-A_CAT1 | rna-NM_001184453.1_CAT1 | cds-NP_075206.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005359.1:55684-56016:+ | gene-YAL044W-A_CBS1585 | rna-NM_001184453.1_CBS1585 | cds-NP_075206.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005343.1:55927-56259:+ | gene-YAL044W-A_CBS436 | rna-NM_001184453.1_CBS436 | cds-NP_075206.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:41829-42161:+ | gene-YAL044W-A_CBS6412 | rna-NM_001184453.1_CBS6412 | cds-NP_075206.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005311.1:53947-54279:+ | gene-YAL044W-A_CBS6413 | rna-NM_001184453.1_CBS6413 | cds-NP_075206.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001522.1:57574-57906:+ | gene-YAL044W-A_CENPK1137D | rna-NM_001184453.1_CENPK1137D | cds-NP_075206.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005471.1:44077-44409:+ | gene-YAL044W-A_EthanolRed | rna-NM_001184453.1_EthanolRed | cds-NP_075206.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005535.1:58019-58351:+ | gene-YAL044W-A_FaliES1 | rna-NM_001184453.1_FaliES1 | cds-NP_075206.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000084.1:29971-30303:+ | gene-YAL044W-A_JAY291 | rna-NM_001184453.1_JAY291 | cds-NP_075206.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005407.1:58625-58957:+ | gene-YAL044W-A_MUCL30387 | rna-NM_001184453.1_MUCL30387 | cds-NP_075206.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005439.1:55172-55504:+ | gene-YAL044W-A_MUCL30388 | rna-NM_001184453.1_MUCL30388 | cds-NP_075206.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005279.1:54488-54820:+ | gene-YAL044W-A_MUCL39482 | rna-NM_001184453.1_MUCL39482 | cds-NP_075206.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005423.1:56830-57162:+ | gene-YAL044W-A_MUCL42920 | rna-NM_001184453.1_MUCL42920 | cds-NP_075206.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011810.1:57395-57727:+ | gene-YAL044W-A_NCIM3186 | rna-NM_001184453.1_NCIM3186 | cds-NP_075206.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005263.1:42353-42685:+ | gene-YAL044W-A_NCYC1407 | rna-NM_001184453.1_NCYC1407 | cds-NP_075206.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994140.1:44235-44567:+ | gene-YAL044W-A_PE2H3 | rna-NM_001184453.1_PE2H3 | cds-NP_075206.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999872.1:43954-44286:+ | gene-YAL044W-A_PE2H4 | rna-NM_001184453.1_PE2H4 | cds-NP_075206.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001133.9:57518-57850:+ | gene-YAL044W-A_S288C | rna-NM_001184453.1_S288C | cds-NP_075206.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000084.1:32128-32460:+ | gene-YAL044W-A_SA1 | rna-NM_001184453.1_SA1 | cds-NP_075206.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005487.1:58229-58561:+ | gene-YAL044W-A_ThermosaccDry | rna-NM_001184453.1_ThermosaccDry | cds-NP_075206.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005455.1:59494-59826:+ | gene-YAL044W-A_VR1 | rna-NM_001184453.1_VR1 | cds-NP_075206.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000002.1:30038-30370:+ | gene-YAL044W-A_ZTW1 | rna-NM_001184453.1_ZTW1 | cds-NP_075206.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047487.1:47734-48066:+ | gene-YAL044W-A_Sparadoxus | rna-NM_001184453.1_Sparadoxus | cds-NP_075206.1_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |