Gene name: BNA4
Reference locus (S288C): YBL098W
Gene biotype: protein_coding
Description: Kynurenine 3-monooxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease
Top 10 interactors (score): BNA5 (0.999); BNA1 (0.999); BNA3 (0.99); BNA7 (0.989); TNA1 (0.97); BNA6 (0.956); BNA2 (0.919); AGX1 (0.906); ARO8 (0.847); NMA1 (0.816); NMA2 (0.816); NPT1 (0.804); ALG3 (0.793); PNP1 (0.788); URH1 (0.787); SIR2 (0.784); QNS1 (0.761); CBC2 (0.752); ERG9 (0.735); FMS1 (0.7)
Homologues (species, bitscore): KMO (Homo sapiens, 289.3); Kmo (Mus musculus, 295.8); kmo (Danio rerio, 287.3); kmo (Xenopus tropicalis, 289.7); Cn (Drosophila melanogaster, 258.1); R07B7.5 (Caenorhabditis elegans, 291.2); CTF2B (Arabidopsis thaliana, 58.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:32714-34096:+ | gene-YBL098W_AKU4011 | rna-NM_001178338.1_AKU4011 | cds-NP_009454.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:23415-24797:+ | gene-YBL098W_BG1 | rna-NM_001178338.1_BG1 | cds-NP_009454.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:33347-34729:+ | gene-YBL098W_Bruggeman | rna-NM_001178338.1_Bruggeman | cds-NP_009454.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:35280-36662:+ | gene-YBL098W_CAT1 | rna-NM_001178338.1_CAT1 | cds-NP_009454.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:24785-26167:+ | gene-YBL098W_CBS1585 | rna-NM_001178338.1_CBS1585 | cds-NP_009454.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:33596-34978:+ | gene-YBL098W_CBS436 | rna-NM_001178338.1_CBS436 | cds-NP_009454.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:24573-25955:+ | gene-YBL098W_CBS6412 | rna-NM_001178338.1_CBS6412 | cds-NP_009454.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:30915-32297:+ | gene-YBL098W_CBS6413 | rna-NM_001178338.1_CBS6413 | cds-NP_009454.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:32763-34145:+ | gene-YBL098W_CENPK1137D | rna-NM_001178338.1_CENPK1137D | cds-NP_009454.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:46957-48339:+ | gene-YBL098W_EthanolRed | rna-NM_001178338.1_EthanolRed | cds-NP_009454.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:47089-48471:+ | gene-YBL098W_FaliES1 | rna-NM_001178338.1_FaliES1 | cds-NP_009454.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000184.1:24108-25490:+ | gene-YBL098W_JAY291 | rna-NM_001178338.1_JAY291 | cds-NP_009454.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:32479-33861:+ | gene-YBL098W_MUCL30387 | rna-NM_001178338.1_MUCL30387 | cds-NP_009454.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:33135-34517:+ | gene-YBL098W_MUCL30388 | rna-NM_001178338.1_MUCL30388 | cds-NP_009454.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:24941-26323:+ | gene-YBL098W_MUCL39482 | rna-NM_001178338.1_MUCL39482 | cds-NP_009454.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:31831-33213:+ | gene-YBL098W_MUCL42920 | rna-NM_001178338.1_MUCL42920 | cds-NP_009454.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:38942-40324:+ | gene-YBL098W_NCIM3186 | rna-NM_001178338.1_NCIM3186 | cds-NP_009454.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:26613-27995:+ | gene-YBL098W_NCYC1407 | rna-NM_001178338.1_NCYC1407 | cds-NP_009454.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:32898-34280:+ | gene-YBL098W_PE2H3 | rna-NM_001178338.1_PE2H3 | cds-NP_009454.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:30530-31912:+ | gene-YBL098W_PE2H4 | rna-NM_001178338.1_PE2H4 | cds-NP_009454.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:39145-40527:+ | gene-YBL098W_S288C | rna-NM_001178338.1_S288C | cds-NP_009454.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:23225-24607:+ | gene-YBL098W_SA1 | rna-NM_001178338.1_SA1 | cds-NP_009454.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:47051-48433:+ | gene-YBL098W_ThermosaccDry | rna-NM_001178338.1_ThermosaccDry | cds-NP_009454.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:29244-30626:+ | gene-YBL098W_VR1 | rna-NM_001178338.1_VR1 | cds-NP_009454.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:24272-25654:+ | gene-YBL098W_ZTW1 | rna-NM_001178338.1_ZTW1 | cds-NP_009454.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:59030-60412:+ | gene-YBL098W_Sparadoxus | rna-NM_001178338.1_Sparadoxus | cds-NP_009454.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |