BNA2 (YJR078W)


Gene profile

Gene name: BNA2
Reference locus (S288C): YJR078W
Gene biotype: protein_coding

Description: Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase; required for de novo biosynthesis of NAD from tryptophan via kynurenine; interacts genetically with telomere capping gene CDC13; regulated by Hst1p and Aftp

Top 10 interactors (score): BNA5 (0.994); BNA7 (0.991); BNA3 (0.96); BNA1 (0.945); ARO8 (0.929); BNA4 (0.919); BNA6 (0.899); NPT1 (0.878); NMA1 (0.816); TRP5 (0.8); NMA2 (0.792); TPA1 (0.786); QNS1 (0.76); TNA1 (0.712); AIM17 (0.647); PNC1 (0.599); ALD3 (0.59); PNS1 (0.584); VMA6 (0.584); HST1 (0.552)

Homologues (species, bitscore): IDO2 (Homo sapiens, 196.1); Ido1 (Mus musculus, 188.7); ido1 (Danio rerio, 190.7); ido1 (Xenopus tropicalis, 146.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:550386-551747:+ gene-YJR078W_AKU4011 rna-NM_001181736.3_AKU4011 cds-NP_012612.3_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:55826-57187:- gene-YJR078W_BG1 rna-NM_001181736.3_BG1 cds-NP_012612.3_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:563900-565261:+ gene-YJR078W_Bruggeman rna-NM_001181736.3_Bruggeman cds-NP_012612.3_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:568302-569663:+ gene-YJR078W_CAT1 rna-NM_001181736.3_CAT1 cds-NP_012612.3_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:562450-563811:+ gene-YJR078W_CBS1585 rna-NM_001181736.3_CBS1585 cds-NP_012612.3_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:580523-581884:+ gene-YJR078W_CBS436 rna-NM_001181736.3_CBS436 cds-NP_012612.3_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:549599-550960:+ gene-YJR078W_CBS6412 rna-NM_001181736.3_CBS6412 cds-NP_012612.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:551895-553256:+ gene-YJR078W_CBS6413 rna-NM_001181736.3_CBS6413 cds-NP_012612.3_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:561221-562582:+ gene-YJR078W_CENPK1137D rna-NM_001181736.3_CENPK1137D cds-NP_012612.3_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:554778-556139:+ gene-YJR078W_EthanolRed rna-NM_001181736.3_EthanolRed cds-NP_012612.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:566244-567605:+ gene-YJR078W_FaliES1 rna-NM_001181736.3_FaliES1 cds-NP_012612.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000054.1:121775-123136:- gene-YJR078W_JAY291 rna-NM_001181736.3_JAY291 cds-NP_012612.3_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:564429-565790:+ gene-YJR078W_MUCL30387 rna-NM_001181736.3_MUCL30387 cds-NP_012612.3_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:561725-563086:+ gene-YJR078W_MUCL30388 rna-NM_001181736.3_MUCL30388 cds-NP_012612.3_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:555911-557272:+ gene-YJR078W_MUCL39482 rna-NM_001181736.3_MUCL39482 cds-NP_012612.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:560157-561518:+ gene-YJR078W_MUCL42920 rna-NM_001181736.3_MUCL42920 cds-NP_012612.3_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:578839-580200:+ gene-YJR078W_NCIM3186 rna-NM_001181736.3_NCIM3186 cds-NP_012612.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:553476-554837:+ gene-YJR078W_NCYC1407 rna-NM_001181736.3_NCYC1407 cds-NP_012612.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:571369-572730:+ gene-YJR078W_PE2H3 rna-NM_001181736.3_PE2H3 cds-NP_012612.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:565067-566428:+ gene-YJR078W_PE2H4 rna-NM_001181736.3_PE2H4 cds-NP_012612.3_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:578860-580221:+ gene-YJR078W_S288C rna-NM_001181736.3_S288C cds-NP_012612.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000038.1:37443-38804:+ gene-YJR078W_SA1 rna-NM_001181736.3_SA1 cds-NP_012612.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:560176-561537:+ gene-YJR078W_ThermosaccDry rna-NM_001181736.3_ThermosaccDry cds-NP_012612.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:562355-563716:+ gene-YJR078W_VR1 rna-NM_001181736.3_VR1 cds-NP_012612.3_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:539573-540935:+ gene-YJR078W_ZTW1 rna-NM_001181736.3_ZTW1 cds-NP_012612.3_ZTW1 99.5 100.0 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:572962-574338:+ gene-YJR078W_Sparadoxus rna-NM_001181736.3_Sparadoxus cds-NP_012612.3_Sparadoxus 89.2 99.7 Verified 1 1 1 False True False False False

Additional files