BMH2 (YDR099W)


Gene profile

Gene name: BMH2
Reference locus (S288C): YDR099W
Gene biotype: protein_coding

Description: 14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; abundance relative to Bmh1p increases during sporulation

Top 10 interactors (score): BMH1 (0.999); MIH1 (0.994); GLC7 (0.989); CHK1 (0.946); NTH1 (0.936); RTG2 (0.936); STE20 (0.934); PIK1 (0.925); FIN1 (0.913); CDC42 (0.907); RSP5 (0.896); MSN5 (0.872); CHC1 (0.868); FRQ1 (0.868); CDC14 (0.848); RTG3 (0.845); RAD53 (0.834); MKS1 (0.818); REG1 (0.806); YCH1 (0.805)

Homologues (species, bitscore): YWHAE (Homo sapiens, 382.1); Ywhae (Mus musculus, 382.1); ywhae2 (Danio rerio, 381.3); ywhae (Xenopus tropicalis, 375.2); SR3-9 (Drosophila melanogaster, 369.8); ftt-2 (Caenorhabditis elegans, 322.8); RCI1A (Arabidopsis thaliana, 372.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:624897-625715:+ gene-YDR099W_AKU4011 rna-NM_001180407.3_AKU4011 cds-NP_010384.3_AKU4011 99.2 99.6 Mismatch 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:499208-500041:- gene-YDR099W_BG1 rna-NM_001180407.3_BG1 cds-NP_010384.3_BG1 98.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:656984-657802:+ gene-YDR099W_Bruggeman rna-NM_001180407.3_Bruggeman cds-NP_010384.3_Bruggeman 99.2 99.6 Mismatch 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:642837-643670:+ gene-YDR099W_CAT1 rna-NM_001180407.3_CAT1 cds-NP_010384.3_CAT1 98.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:615916-616734:+ gene-YDR099W_CBS1585 rna-NM_001180407.3_CBS1585 cds-NP_010384.3_CBS1585 99.2 99.6 Mismatch 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:641307-642128:+ gene-YDR099W_CBS436 rna-NM_001180407.3_CBS436 cds-NP_010384.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:612331-613149:+ gene-YDR099W_CBS6412 rna-NM_001180407.3_CBS6412 cds-NP_010384.3_CBS6412 99.2 99.6 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:640862-641680:+ gene-YDR099W_CBS6413 rna-NM_001180407.3_CBS6413 cds-NP_010384.3_CBS6413 99.2 99.6 Mismatch 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:646344-647162:+ gene-YDR099W_CENPK1137D rna-NM_001180407.3_CENPK1137D cds-NP_010384.3_CENPK1137D 99.2 99.6 Mismatch 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:626682-627500:+ gene-YDR099W_EthanolRed rna-NM_001180407.3_EthanolRed cds-NP_010384.3_EthanolRed 99.2 99.6 Mismatch 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:633476-634294:+ gene-YDR099W_FaliES1 rna-NM_001180407.3_FaliES1 cds-NP_010384.3_FaliES1 99.2 99.6 Mismatch 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000125.1:2138-2962:+ gene-YDR099W_JAY291 rna-NM_001180407.3_JAY291 cds-NP_010384.3_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:642885-643703:+ gene-YDR099W_MUCL30387 rna-NM_001180407.3_MUCL30387 cds-NP_010384.3_MUCL30387 99.5 99.6 Mismatch 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:631914-632732:+ gene-YDR099W_MUCL30388 rna-NM_001180407.3_MUCL30388 cds-NP_010384.3_MUCL30388 99.2 99.6 Mismatch 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:617286-618104:+ gene-YDR099W_MUCL39482 rna-NM_001180407.3_MUCL39482 cds-NP_010384.3_MUCL39482 99.2 99.6 Mismatch 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:555231-556049:+ gene-YDR099W_MUCL42920 rna-NM_001180407.3_MUCL42920 cds-NP_010384.3_MUCL42920 99.3 99.6 Mismatch 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:653530-654351:+ gene-YDR099W_NCIM3186 rna-NM_001180407.3_NCIM3186 cds-NP_010384.3_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:616197-617015:+ gene-YDR099W_NCYC1407 rna-NM_001180407.3_NCYC1407 cds-NP_010384.3_NCYC1407 99.2 99.6 Mismatch 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:636005-636829:+ gene-YDR099W_PE2H3 rna-NM_001180407.3_PE2H3 cds-NP_010384.3_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:635310-636134:+ gene-YDR099W_PE2H4 rna-NM_001180407.3_PE2H4 cds-NP_010384.3_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:653607-654428:+ gene-YDR099W_S288C rna-NM_001180407.3_S288C cds-NP_010384.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:2219-3043:+ gene-YDR099W_SA1 rna-NM_001180407.3_SA1 cds-NP_010384.3_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:633005-633823:+ gene-YDR099W_ThermosaccDry rna-NM_001180407.3_ThermosaccDry cds-NP_010384.3_ThermosaccDry 99.2 99.6 Mismatch 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:645901-646734:+ gene-YDR099W_VR1 rna-NM_001180407.3_VR1 cds-NP_010384.3_VR1 98.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:630589-631407:+ gene-YDR099W_ZTW1 rna-NM_001180407.3_ZTW1 cds-NP_010384.3_ZTW1 99.2 99.6 Mismatch 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:635221-636039:+ gene-YDR099W_Sparadoxus rna-NM_001180407.3_Sparadoxus cds-NP_010384.3_Sparadoxus 93.3 99.6 Verified 1 1 1 False True False False False

Additional files