Gene name: BMH1
Reference locus (S288C): YER177W
Gene biotype: protein_coding
Description: 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, spindle position checkpoint; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; antiapoptotic gene similar to human 14-3-3; BMH1 has a paralog, BMH2, that arose from whole genome duplication
Top 10 interactors (score): BMH2 (0.999); NTH1 (0.997); GLC7 (0.995); MIH1 (0.987); MKS1 (0.987); CDC25 (0.969); RTG2 (0.965); STE20 (0.964); CHK1 (0.963); FIN1 (0.947); CDC42 (0.94); REG1 (0.929); CDC14 (0.923); TPK1 (0.889); RAD53 (0.887); RSP5 (0.886); RTG3 (0.885); FRQ1 (0.87); CHC1 (0.87); ACM1 (0.866)
Homologues (species, bitscore): YWHAE (Homo sapiens, 375.9); Ywhae (Mus musculus, 375.9); ywhae2 (Danio rerio, 371.3); ywhae (Xenopus tropicalis, 371.7); SR3-9 (Drosophila melanogaster, 371.7); ftt-2 (Caenorhabditis elegans, 320.9); RCI1A (Arabidopsis thaliana, 367.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:527122-527928:+ | gene-YER177W_AKU4011 | rna-NM_001179067.3_AKU4011 | cds-NP_011104.3_AKU4011 | 98.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000176.1:5440-6243:- | gene-YER177W_BG1 | rna-NM_001179067.3_BG1 | cds-NP_011104.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:539869-540675:+ | gene-YER177W_Bruggeman | rna-NM_001179067.3_Bruggeman | cds-NP_011104.3_Bruggeman | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:526459-527262:+ | gene-YER177W_CAT1 | rna-NM_001179067.3_CAT1 | cds-NP_011104.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:526929-527732:+ | gene-YER177W_CBS1585 | rna-NM_001179067.3_CBS1585 | cds-NP_011104.3_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:536821-537624:+ | gene-YER177W_CBS436 | rna-NM_001179067.3_CBS436 | cds-NP_011104.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:524906-525709:+ | gene-YER177W_CBS6412 | rna-NM_001179067.3_CBS6412 | cds-NP_011104.3_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:533475-534278:+ | gene-YER177W_CBS6413 | rna-NM_001179067.3_CBS6413 | cds-NP_011104.3_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:543377-544180:+ | gene-YER177W_CENPK1137D | rna-NM_001179067.3_CENPK1137D | cds-NP_011104.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:533099-533896:+ | gene-YER177W_EthanolRed | rna-NM_001179067.3_EthanolRed | cds-NP_011104.3_EthanolRed | 99.0 | 99.2 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:534035-534832:+ | gene-YER177W_FaliES1 | rna-NM_001179067.3_FaliES1 | cds-NP_011104.3_FaliES1 | 99.0 | 99.2 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000169.1:5063-5866:- | gene-YER177W_JAY291 | rna-NM_001179067.3_JAY291 | cds-NP_011104.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:527182-527985:+ | gene-YER177W_MUCL30387 | rna-NM_001179067.3_MUCL30387 | cds-NP_011104.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:530095-530898:+ | gene-YER177W_MUCL30388 | rna-NM_001179067.3_MUCL30388 | cds-NP_011104.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:522887-523690:+ | gene-YER177W_MUCL39482 | rna-NM_001179067.3_MUCL39482 | cds-NP_011104.3_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:537414-538217:+ | gene-YER177W_MUCL42920 | rna-NM_001179067.3_MUCL42920 | cds-NP_011104.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:545610-546413:+ | gene-YER177W_NCIM3186 | rna-NM_001179067.3_NCIM3186 | cds-NP_011104.3_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:532342-533145:+ | gene-YER177W_NCYC1407 | rna-NM_001179067.3_NCYC1407 | cds-NP_011104.3_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:548284-549087:+ | gene-YER177W_PE2H3 | rna-NM_001179067.3_PE2H3 | cds-NP_011104.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:538217-539020:+ | gene-YER177W_PE2H4 | rna-NM_001179067.3_PE2H4 | cds-NP_011104.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:545611-546414:+ | gene-YER177W_S288C | rna-NM_001179067.3_S288C | cds-NP_011104.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000030.1:97766-98569:+ | gene-YER177W_SA1 | rna-NM_001179067.3_SA1 | cds-NP_011104.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:534835-535632:+ | gene-YER177W_ThermosaccDry | rna-NM_001179067.3_ThermosaccDry | cds-NP_011104.3_ThermosaccDry | 99.0 | 99.2 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:528120-528923:+ | gene-YER177W_VR1 | rna-NM_001179067.3_VR1 | cds-NP_011104.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000011.1:47683-48486:+ | gene-YER177W_ZTW1 | rna-NM_001179067.3_ZTW1 | cds-NP_011104.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:536103-536903:+ | gene-YER177W_Sparadoxus | rna-NM_001179067.3_Sparadoxus | cds-NP_011104.3_Sparadoxus | 93.2 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |