Gene name: BIR1
Reference locus (S288C): YJR089W
Gene biotype: protein_coding
Description: Protein BIR1; Subunit of chromosomal passenger complex (CPC); CPC is comprised of Ipl1p-Sli15p-Bir1p-Nbl1p and regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension; relative distribution to shortened microtubules increases upon DNA replication stress; sumoylated in an Mms21p-dependent manner; human survivin homolog
Top 10 interactors (score): SLI15 (0.999); IPL1 (0.999); CBF2 (0.997); NBL1 (0.989); NDC80 (0.926); NMA111 (0.912); AIF1 (0.903); BUB1 (0.902); MAD2 (0.888); NUC1 (0.874); UBC13 (0.871); CEP3 (0.853); ASE1 (0.833); SGO1 (0.824); CSE4 (0.812); CIN8 (0.81); MCD1 (0.805); MCA1 (0.798); TSA2 (0.795); DAM1 (0.791)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:559247-562111:+ | gene-YJR089W_AKU4011 | rna-NM_001181746.3_AKU4011 | cds-NP_012622.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:45461-48325:- | gene-YJR089W_BG1 | rna-NM_001181746.3_BG1 | cds-NP_012622.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:572761-575625:+ | gene-YJR089W_Bruggeman | rna-NM_001181746.3_Bruggeman | cds-NP_012622.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:577160-580024:+ | gene-YJR089W_CAT1 | rna-NM_001181746.3_CAT1 | cds-NP_012622.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:571311-574175:+ | gene-YJR089W_CBS1585 | rna-NM_001181746.3_CBS1585 | cds-NP_012622.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:589400-592264:+ | gene-YJR089W_CBS436 | rna-NM_001181746.3_CBS436 | cds-NP_012622.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:558459-561323:+ | gene-YJR089W_CBS6412 | rna-NM_001181746.3_CBS6412 | cds-NP_012622.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:560753-563617:+ | gene-YJR089W_CBS6413 | rna-NM_001181746.3_CBS6413 | cds-NP_012622.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:570074-572938:+ | gene-YJR089W_CENPK1137D | rna-NM_001181746.3_CENPK1137D | cds-NP_012622.3_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:563637-566501:+ | gene-YJR089W_EthanolRed | rna-NM_001181746.3_EthanolRed | cds-NP_012622.3_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:575103-577967:+ | gene-YJR089W_FaliES1 | rna-NM_001181746.3_FaliES1 | cds-NP_012622.3_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:111418-114282:- | gene-YJR089W_JAY291 | rna-NM_001181746.3_JAY291 | cds-NP_012622.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:573291-576155:+ | gene-YJR089W_MUCL30387 | rna-NM_001181746.3_MUCL30387 | cds-NP_012622.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:570587-573451:+ | gene-YJR089W_MUCL30388 | rna-NM_001181746.3_MUCL30388 | cds-NP_012622.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:564771-567635:+ | gene-YJR089W_MUCL39482 | rna-NM_001181746.3_MUCL39482 | cds-NP_012622.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:569017-571881:+ | gene-YJR089W_MUCL42920 | rna-NM_001181746.3_MUCL42920 | cds-NP_012622.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:587697-590561:+ | gene-YJR089W_NCIM3186 | rna-NM_001181746.3_NCIM3186 | cds-NP_012622.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:562337-565201:+ | gene-YJR089W_NCYC1407 | rna-NM_001181746.3_NCYC1407 | cds-NP_012622.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:580234-583098:+ | gene-YJR089W_PE2H3 | rna-NM_001181746.3_PE2H3 | cds-NP_012622.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:573923-576787:+ | gene-YJR089W_PE2H4 | rna-NM_001181746.3_PE2H4 | cds-NP_012622.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:587718-590582:+ | gene-YJR089W_S288C | rna-NM_001181746.3_S288C | cds-NP_012622.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:46299-49163:+ | gene-YJR089W_SA1 | rna-NM_001181746.3_SA1 | cds-NP_012622.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:569037-571901:+ | gene-YJR089W_ThermosaccDry | rna-NM_001181746.3_ThermosaccDry | cds-NP_012622.3_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:571192-574056:+ | gene-YJR089W_VR1 | rna-NM_001181746.3_VR1 | cds-NP_012622.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:548432-551295:+ | gene-YJR089W_ZTW1 | rna-NM_001181746.3_ZTW1 | cds-NP_012622.3_ZTW1 | 99.3 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:581797-584682:+ | gene-YJR089W_Sparadoxus | rna-NM_001181746.3_Sparadoxus | cds-NP_012622.3_Sparadoxus | 82.7 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |