BIO3 (YNR058W)


Gene profile

Gene name: BIO3
Reference locus (S288C): YNR058W
Gene biotype: protein_coding

Description: 7,8-diamino-pelargonic acid aminotransferase (DAPA); catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; BIO3 and BIO4 were acquired by horizontal gene transfer (HGT) from bacteria; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily

Top 10 interactors (score): BIO4 (0.999); BIO2 (0.998); BIO5 (0.997); ARG5,6 (0.98); VHT1 (0.964); AAD10 (0.92); YJR154W (0.908); ARG4 (0.793); UGA1 (0.749); ARG3 (0.749); YPL245W (0.746); ARG2 (0.725); ARG1 (0.708); DUG1 (0.677); VHR1 (0.674); HIS4 (0.648); ARG7 (0.647); HEM2 (0.636); HEM12 (0.634); TRP3 (0.62)

Homologues (species, bitscore): OAT (Homo sapiens, 84.0); Oat (Mus musculus, 84.3); oat (Danio rerio, 81.6); oat.1 (Xenopus tropicalis, 89.0); Oat (Drosophila melanogaster, 94.0); C16A3.10 (Caenorhabditis elegans, 93.2); POP2 (Arabidopsis thaliana, 114.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:216418-217860:- gene-YNR058W_AKU4011 rna-NM_001183235.1_AKU4011 cds-NP_014456.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:625862-627304:+ gene-YNR058W_BG1 rna-NM_001183235.1_BG1 cds-NP_014456.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:736022-737464:+ gene-YNR058W_Bruggeman rna-NM_001183235.1_Bruggeman cds-NP_014456.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:770465-771907:+ gene-YNR058W_CAT1 rna-NM_001183235.1_CAT1 cds-NP_014456.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:723178-724620:+ gene-YNR058W_CBS1585 rna-NM_001183235.1_CBS1585 cds-NP_014456.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:786037-787479:+ gene-YNR058W_CBS436 rna-NM_001183235.1_CBS436 cds-NP_014456.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:712160-713602:+ gene-YNR058W_CBS6412 rna-NM_001183235.1_CBS6412 cds-NP_014456.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:713841-715283:+ gene-YNR058W_CBS6413 rna-NM_001183235.1_CBS6413 cds-NP_014456.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:727927-729369:+ gene-YNR058W_CENPK1137D rna-NM_001183235.1_CENPK1137D cds-NP_014456.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:718819-720261:+ gene-YNR058W_EthanolRed rna-NM_001183235.1_EthanolRed cds-NP_014456.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:710011-711453:+ gene-YNR058W_FaliES1 rna-NM_001183235.1_FaliES1 cds-NP_014456.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000005.1:16283-17725:- gene-YNR058W_JAY291 rna-NM_001183235.1_JAY291 cds-NP_014456.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:733981-735423:+ gene-YNR058W_MUCL30387 rna-NM_001183235.1_MUCL30387 cds-NP_014456.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:775589-777031:+ gene-YNR058W_MUCL30388 rna-NM_001183235.1_MUCL30388 cds-NP_014456.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:714644-716086:+ gene-YNR058W_MUCL39482 rna-NM_001183235.1_MUCL39482 cds-NP_014456.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:721037-722479:+ gene-YNR058W_MUCL42920 rna-NM_001183235.1_MUCL42920 cds-NP_014456.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:734260-735702:+ gene-YNR058W_NCIM3186 rna-NM_001183235.1_NCIM3186 cds-NP_014456.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:717160-718602:+ gene-YNR058W_NCYC1407 rna-NM_001183235.1_NCYC1407 cds-NP_014456.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:718711-720153:+ gene-YNR058W_PE2H3 rna-NM_001183235.1_PE2H3 cds-NP_014456.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:720113-721555:+ gene-YNR058W_PE2H4 rna-NM_001183235.1_PE2H4 cds-NP_014456.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:734291-735733:+ gene-YNR058W_S288C rna-NM_001183235.1_S288C cds-NP_014456.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000087.1:34114-35556:- gene-YNR058W_SA1 rna-NM_001183235.1_SA1 cds-NP_014456.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:710354-711796:+ gene-YNR058W_ThermosaccDry rna-NM_001183235.1_ThermosaccDry cds-NP_014456.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:753599-755041:+ gene-YNR058W_VR1 rna-NM_001183235.1_VR1 cds-NP_014456.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:620120-621562:+ gene-YNR058W_ZTW1 rna-NM_001183235.1_ZTW1 cds-NP_014456.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:724369-725811:+ gene-YNR058W_Sparadoxus rna-NM_001183235.1_Sparadoxus cds-NP_014456.1_Sparadoxus 91.1 100.0 Verified 1 1 1 False True False False False

Additional files