Gene name: BFA1
Reference locus (S288C): YJR053W
Gene biotype: protein_coding
Description: Mitotic check point protein BFA1; Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p; contributes to GAP activity, inactivating Tem1 by stimulating GTP hydrolysis following damage or misalignment of the mitotic spindle; functions as a guanine-nucleotide exchange inhibitor (GDI) for Tem1p; involved in multiple cell cycle checkpoint pathways that control mitotic exit; required when telomeres are damaged, but not for all types of chromosomal DNA damage; phosphorylated by the Polo-like kinase Cdc5p; To S.pombe byr4
Top 10 interactors (score): BUB2 (0.999); TEM1 (0.999); CDC5 (0.998); KIN4 (0.995); LTE1 (0.985); CDC14 (0.974); KAR9 (0.962); SPC72 (0.94); MAD2 (0.931); DBF2 (0.927); MPS1 (0.927); CDC15 (0.924); BUB3 (0.92); MOB1 (0.92); DYN1 (0.915); BIM1 (0.913); NUD1 (0.911); MAD1 (0.909); BUB1 (0.909); MAD3 (0.909)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:505715-507439:+ | gene-YJR053W_AKU4011 | rna-NM_001181711.3_AKU4011 | cds-NP_012587.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:105553-107277:- | gene-YJR053W_BG1 | rna-NM_001181711.3_BG1 | cds-NP_012587.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:519764-521488:+ | gene-YJR053W_Bruggeman | rna-NM_001181711.3_Bruggeman | cds-NP_012587.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:523929-525653:+ | gene-YJR053W_CAT1 | rna-NM_001181711.3_CAT1 | cds-NP_012587.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:517784-519508:+ | gene-YJR053W_CBS1585 | rna-NM_001181711.3_CBS1585 | cds-NP_012587.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:536243-537967:+ | gene-YJR053W_CBS436 | rna-NM_001181711.3_CBS436 | cds-NP_012587.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:505499-507223:+ | gene-YJR053W_CBS6412 | rna-NM_001181711.3_CBS6412 | cds-NP_012587.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:507744-509468:+ | gene-YJR053W_CBS6413 | rna-NM_001181711.3_CBS6413 | cds-NP_012587.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:516390-518114:+ | gene-YJR053W_CENPK1137D | rna-NM_001181711.3_CENPK1137D | cds-NP_012587.3_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:510627-512351:+ | gene-YJR053W_EthanolRed | rna-NM_001181711.3_EthanolRed | cds-NP_012587.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:521844-523568:+ | gene-YJR053W_FaliES1 | rna-NM_001181711.3_FaliES1 | cds-NP_012587.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000352.1:4854-6578:- | gene-YJR053W_JAY291 | rna-NM_001181711.3_JAY291 | cds-NP_012587.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:520301-522025:+ | gene-YJR053W_MUCL30387 | rna-NM_001181711.3_MUCL30387 | cds-NP_012587.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:517576-519300:+ | gene-YJR053W_MUCL30388 | rna-NM_001181711.3_MUCL30388 | cds-NP_012587.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:511242-512966:+ | gene-YJR053W_MUCL39482 | rna-NM_001181711.3_MUCL39482 | cds-NP_012587.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:516012-517736:+ | gene-YJR053W_MUCL42920 | rna-NM_001181711.3_MUCL42920 | cds-NP_012587.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:534006-535730:+ | gene-YJR053W_NCIM3186 | rna-NM_001181711.3_NCIM3186 | cds-NP_012587.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:509099-510823:+ | gene-YJR053W_NCYC1407 | rna-NM_001181711.3_NCYC1407 | cds-NP_012587.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:526995-528719:+ | gene-YJR053W_PE2H3 | rna-NM_001181711.3_PE2H3 | cds-NP_012587.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:520691-522415:+ | gene-YJR053W_PE2H4 | rna-NM_001181711.3_PE2H4 | cds-NP_012587.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:534027-535751:+ | gene-YJR053W_S288C | rna-NM_001181711.3_S288C | cds-NP_012587.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000110.1:15593-17317:+ | gene-YJR053W_SA1 | rna-NM_001181711.3_SA1 | cds-NP_012587.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:515532-517256:+ | gene-YJR053W_ThermosaccDry | rna-NM_001181711.3_ThermosaccDry | cds-NP_012587.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:518027-519751:+ | gene-YJR053W_VR1 | rna-NM_001181711.3_VR1 | cds-NP_012587.3_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:495415-497139:+ | gene-YJR053W_ZTW1 | rna-NM_001181711.3_ZTW1 | cds-NP_012587.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:521727-523454:+ | gene-YJR053W_Sparadoxus | rna-NM_001181711.3_Sparadoxus | cds-NP_012587.3_Sparadoxus | 88.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |