BEM3 (YPL115C)


Gene profile

Gene name: BEM3
Reference locus (S288C): YPL115C
Gene biotype: protein_coding

Description: GTPase-activating protein BEM3; Rho GTPase activating protein (RhoGAP); involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly

Top 10 interactors (score): CDC42 (0.998); BEM1 (0.936); CDC24 (0.931); BNI1 (0.916); CLA4 (0.915); RDI1 (0.881); LRG1 (0.831); RHO1 (0.816); RSR1 (0.786); STE20 (0.765); EPO1 (0.761); BUD5 (0.756); SPA2 (0.743); SEC4 (0.74); LSB1 (0.739); KSS1 (0.73); RHO4 (0.728); ACT1 (0.72); BOI2 (0.718); GIC2 (0.716)

Homologues (species, bitscore): ARHGAP24 (Homo sapiens, 88.6); Arhgap24 (Mus musculus, 87.4); arhgap24 (Danio rerio, 90.1); arhgap21 (Xenopus tropicalis, 88.6); RhoGAP1A (Drosophila melanogaster, 80.1); pac-1 (Caenorhabditis elegans, 68.9); AT1G08340 (Arabidopsis thaliana, 60.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:309739-313125:- gene-YPL115C_AKU4011 rna-NM_001183929.1_AKU4011 cds-NP_015210.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:515496-518882:- gene-YPL115C_BG1 rna-NM_001183929.1_BG1 cds-NP_015210.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:335745-339131:- gene-YPL115C_Bruggeman rna-NM_001183929.1_Bruggeman cds-NP_015210.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:332412-335798:- gene-YPL115C_CAT1 rna-NM_001183929.1_CAT1 cds-NP_015210.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:313812-317198:- gene-YPL115C_CBS1585 rna-NM_001183929.1_CBS1585 cds-NP_015210.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:328488-331874:- gene-YPL115C_CBS436 rna-NM_001183929.1_CBS436 cds-NP_015210.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:318481-321867:- gene-YPL115C_CBS6412 rna-NM_001183929.1_CBS6412 cds-NP_015210.1_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:310448-313834:- gene-YPL115C_CBS6413 rna-NM_001183929.1_CBS6413 cds-NP_015210.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:332049-335435:- gene-YPL115C_CENPK1137D rna-NM_001183929.1_CENPK1137D cds-NP_015210.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:308429-311815:- gene-YPL115C_EthanolRed rna-NM_001183929.1_EthanolRed cds-NP_015210.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:316021-319407:- gene-YPL115C_FaliES1 rna-NM_001183929.1_FaliES1 cds-NP_015210.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000007.1:46409-49795:+ gene-YPL115C_JAY291 rna-NM_001183929.1_JAY291 cds-NP_015210.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:326984-330370:- gene-YPL115C_MUCL30387 rna-NM_001183929.1_MUCL30387 cds-NP_015210.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:325255-328641:- gene-YPL115C_MUCL30388 rna-NM_001183929.1_MUCL30388 cds-NP_015210.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:307141-310527:- gene-YPL115C_MUCL39482 rna-NM_001183929.1_MUCL39482 cds-NP_015210.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:364384-367770:- gene-YPL115C_MUCL42920 rna-NM_001183929.1_MUCL42920 cds-NP_015210.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:332083-335469:- gene-YPL115C_NCIM3186 rna-NM_001183929.1_NCIM3186 cds-NP_015210.1_NCIM3186 97.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:313594-316980:- gene-YPL115C_NCYC1407 rna-NM_001183929.1_NCYC1407 cds-NP_015210.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:321087-324473:- gene-YPL115C_PE2H3 rna-NM_001183929.1_PE2H3 cds-NP_015210.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:320710-324096:- gene-YPL115C_PE2H4 rna-NM_001183929.1_PE2H4 cds-NP_015210.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:332100-335486:- gene-YPL115C_S288C rna-NM_001183929.1_S288C cds-NP_015210.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000012.1:38195-41581:+ gene-YPL115C_SA1 rna-NM_001183929.1_SA1 cds-NP_015210.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:315819-319205:- gene-YPL115C_ThermosaccDry rna-NM_001183929.1_ThermosaccDry cds-NP_015210.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:330799-334185:- gene-YPL115C_VR1 rna-NM_001183929.1_VR1 cds-NP_015210.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:315144-318530:- gene-YPL115C_ZTW1 rna-NM_001183929.1_ZTW1 cds-NP_015210.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:316859-320239:- gene-YPL115C_Sparadoxus rna-NM_001183929.1_Sparadoxus cds-NP_015210.1_Sparadoxus 89.3 99.6 Verified 1 1 1 False True False False False

Additional files