BDF2 (YDL070W)


Gene profile

Gene name: BDF2
Reference locus (S288C): YDL070W
Gene biotype: protein_coding

Description: Bromodomain-containing factor 2; Protein involved in transcription initiation; acts at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p; protein abundance increases in response to DNA replication stress; BDF2 has a paralog, BDF1, that arose from the whole genome duplication

Top 10 interactors (score): TAF7 (0.95); TAF1 (0.947); BDF1 (0.926); HHF1 (0.892); DBP9 (0.854); DBP10 (0.854); INO80 (0.835); HTZ1 (0.822); SWR1 (0.778); SPT15 (0.739); DHR2 (0.717); BUD23 (0.705); SPT16 (0.697); DRS1 (0.694); TSR1 (0.682); HCA4 (0.678); HST1 (0.673); DBP3 (0.669); DBP7 (0.669); HHF2 (0.665)

Homologues (species, bitscore): BRDT (Homo sapiens, 161.8); Brdt (Mus musculus, 170.2); brdt (Danio rerio, 165.2); brd2 (Xenopus tropicalis, 154.5); fs(1)h (Drosophila melanogaster, 105.5); bet-1 (Caenorhabditis elegans, 139.4); NPX1 (Arabidopsis thaliana, 97.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:315628-317544:+ gene-YDL070W_AKU4011 rna-NM_001180129.1_AKU4011 cds-NP_010213.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:232513-234429:- gene-YDL070W_BG1 rna-NM_001180129.1_BG1 cds-NP_010213.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:333412-335328:+ gene-YDL070W_Bruggeman rna-NM_001180129.1_Bruggeman cds-NP_010213.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:329779-331695:+ gene-YDL070W_CAT1 rna-NM_001180129.1_CAT1 cds-NP_010213.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:313881-315797:+ gene-YDL070W_CBS1585 rna-NM_001180129.1_CBS1585 cds-NP_010213.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:330574-332490:+ gene-YDL070W_CBS436 rna-NM_001180129.1_CBS436 cds-NP_010213.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:311969-313885:+ gene-YDL070W_CBS6412 rna-NM_001180129.1_CBS6412 cds-NP_010213.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:331960-333876:+ gene-YDL070W_CBS6413 rna-NM_001180129.1_CBS6413 cds-NP_010213.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:329847-331763:+ gene-YDL070W_CENPK1137D rna-NM_001180129.1_CENPK1137D cds-NP_010213.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:326431-328347:+ gene-YDL070W_EthanolRed rna-NM_001180129.1_EthanolRed cds-NP_010213.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:332678-334594:+ gene-YDL070W_FaliES1 rna-NM_001180129.1_FaliES1 cds-NP_010213.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000010.1:102689-104605:+ gene-YDL070W_JAY291 rna-NM_001180129.1_JAY291 cds-NP_010213.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:330803-332719:+ gene-YDL070W_MUCL30387 rna-NM_001180129.1_MUCL30387 cds-NP_010213.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:321928-323844:+ gene-YDL070W_MUCL30388 rna-NM_001180129.1_MUCL30388 cds-NP_010213.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:314985-316901:+ gene-YDL070W_MUCL39482 rna-NM_001180129.1_MUCL39482 cds-NP_010213.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:236998-238914:+ gene-YDL070W_MUCL42920 rna-NM_001180129.1_MUCL42920 cds-NP_010213.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:330947-332863:+ gene-YDL070W_NCIM3186 rna-NM_001180129.1_NCIM3186 cds-NP_010213.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:315009-316925:+ gene-YDL070W_NCYC1407 rna-NM_001180129.1_NCYC1407 cds-NP_010213.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:321807-323723:+ gene-YDL070W_PE2H3 rna-NM_001180129.1_PE2H3 cds-NP_010213.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:321806-323722:+ gene-YDL070W_PE2H4 rna-NM_001180129.1_PE2H4 cds-NP_010213.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:331024-332940:+ gene-YDL070W_S288C rna-NM_001180129.1_S288C cds-NP_010213.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:101993-103909:- gene-YDL070W_SA1 rna-NM_001180129.1_SA1 cds-NP_010213.1_SA1 99.7 99.9 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:332130-334046:+ gene-YDL070W_ThermosaccDry rna-NM_001180129.1_ThermosaccDry cds-NP_010213.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:334207-336610:+ gene-YDL070W_VR1 rna-NM_001180129.1_VR1 cds-NP_010213.1_VR1 79.6 100.0 Unannotated 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:330068-331984:+ gene-YDL070W_ZTW1 rna-NM_001180129.1_ZTW1 cds-NP_010213.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:332192-334102:+ gene-YDL070W_Sparadoxus rna-NM_001180129.1_Sparadoxus cds-NP_010213.1_Sparadoxus 91.8 99.6 Verified 1 1 1 False True False False False

Additional files