BAG7 (YOR134W)


Gene profile

Gene name: BAG7
Reference locus (S288C): YOR134W
Gene biotype: protein_coding

Description: Rho-GTPase-activating protein BAG7; Rho GTPase activating protein (RhoGAP); stimulates the intrinsic GTPase activity of Rho1p, which plays a bud growth by regulating actin cytoskeleton organization and cell wall biosynthesis, resulting in the downregulation of Rho1p; structurally and functionally related to Sac7p; BAG7 has a paralog, SAC7, that arose from the whole genome duplication

Top 10 interactors (score): RHO1 (0.993); RHO5 (0.96); RHO2 (0.955); CDC42 (0.947); RHO3 (0.943); RHO4 (0.943); GEM1 (0.932); RGD2 (0.748); YIL029C (0.711); SMC2 (0.697); KNH1 (0.65); MPS1 (0.644); BEM2 (0.617); ROM2 (0.58); COP1 (0.574); KIP1 (0.561); CIN8 (0.561); BZZ1 (0.535); SAC7 (0.535); BRR2 (0.526)

Homologues (species, bitscore): GMIP (Homo sapiens, 93.2); Gmip (Mus musculus, 84.3); si:dkey-191m6.4 (Danio rerio, 88.2); arhgap25 (Xenopus tropicalis, 75.5); RhoGAP54D (Drosophila melanogaster, 74.3); gei-1 (Caenorhabditis elegans, 77.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:582017-583243:+ gene-YOR134W_AKU4011 rna-NM_001183553.3_AKU4011 cds-NP_014777.3_AKU4011 99.1 99.7 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000171.1:15406-16635:- gene-YOR134W_BG1 rna-NM_001183553.3_BG1 cds-NP_014777.3_BG1 99.6 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:566176-567402:+ gene-YOR134W_Bruggeman rna-NM_001183553.3_Bruggeman cds-NP_014777.3_Bruggeman 99.2 99.7 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:566202-567428:+ gene-YOR134W_CAT1 rna-NM_001183553.3_CAT1 cds-NP_014777.3_CAT1 99.2 99.7 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:558197-559423:+ gene-YOR134W_CBS1585 rna-NM_001183553.3_CBS1585 cds-NP_014777.3_CBS1585 99.1 99.7 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:562901-564130:+ gene-YOR134W_CBS436 rna-NM_001183553.3_CBS436 cds-NP_014777.3_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:555686-556912:+ gene-YOR134W_CBS6412 rna-NM_001183553.3_CBS6412 cds-NP_014777.3_CBS6412 99.1 99.7 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:564478-565704:+ gene-YOR134W_CBS6413 rna-NM_001183553.3_CBS6413 cds-NP_014777.3_CBS6413 99.1 99.7 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:578320-579549:+ gene-YOR134W_CENPK1137D rna-NM_001183553.3_CENPK1137D cds-NP_014777.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:558346-559560:+ gene-YOR134W_EthanolRed rna-NM_001183553.3_EthanolRed cds-NP_014777.3_EthanolRed 98.1 98.7 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:563199-564413:+ gene-YOR134W_FaliES1 rna-NM_001183553.3_FaliES1 cds-NP_014777.3_FaliES1 98.1 98.7 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000070.1:79138-80367:- gene-YOR134W_JAY291 rna-NM_001183553.3_JAY291 cds-NP_014777.3_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:570734-571963:+ gene-YOR134W_MUCL30387 rna-NM_001183553.3_MUCL30387 cds-NP_014777.3_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:576818-578044:+ gene-YOR134W_MUCL30388 rna-NM_001183553.3_MUCL30388 cds-NP_014777.3_MUCL30388 99.2 99.7 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:566272-567498:+ gene-YOR134W_MUCL39482 rna-NM_001183553.3_MUCL39482 cds-NP_014777.3_MUCL39482 99.1 99.7 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:581867-583093:+ gene-YOR134W_MUCL42920 rna-NM_001183553.3_MUCL42920 cds-NP_014777.3_MUCL42920 99.3 99.7 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:578453-579682:+ gene-YOR134W_NCIM3186 rna-NM_001183553.3_NCIM3186 cds-NP_014777.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:572538-573764:+ gene-YOR134W_NCYC1407 rna-NM_001183553.3_NCYC1407 cds-NP_014777.3_NCYC1407 99.1 99.7 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:571041-572273:+ gene-YOR134W_PE2H3 rna-NM_001183553.3_PE2H3 cds-NP_014777.3_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:581418-582650:+ gene-YOR134W_PE2H4 rna-NM_001183553.3_PE2H4 cds-NP_014777.3_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:578564-579793:+ gene-YOR134W_S288C rna-NM_001183553.3_S288C cds-NP_014777.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:1028-2257:+ gene-YOR134W_SA1 rna-NM_001183553.3_SA1 cds-NP_014777.3_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:562382-563596:+ gene-YOR134W_ThermosaccDry rna-NM_001183553.3_ThermosaccDry cds-NP_014777.3_ThermosaccDry 98.1 98.7 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:626040-627269:+ gene-YOR134W_VR1 rna-NM_001183553.3_VR1 cds-NP_014777.3_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:295815-297041:+ gene-YOR134W_ZTW1 rna-NM_001183553.3_ZTW1 cds-NP_014777.3_ZTW1 99.3 99.7 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:567241-568446:+ gene-YOR134W_Sparadoxus rna-NM_001183553.3_Sparadoxus cds-NP_014777.3_Sparadoxus 85.3 97.7 Verified 1 1 1 False True False False False

Additional files