Gene name: AYR1
Reference locus (S288C): YIL124W
Gene biotype: protein_coding
Description: Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase; NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase involved in phosphatidic acid biosynthesis; lipid droplet triacylglycerol lipase involved in the mobilization of non-polar lipids; found in lipid particles, the endoplasmic reticulum and the mitochondrial outer membrane; required for spore germination; role in cell wall biosynthesis; capable of metabolizing steroid hormones; oleic acid inducible; Belongs to the short-chain dehydrogenases/reductases (SDR) family
Top 10 interactors (score): TGL4 (0.984); TGL5 (0.983); GPT2 (0.982); SCT1 (0.976); LOA1 (0.973); ALE1 (0.973); TGL3 (0.939); SLC1 (0.926); TGL1 (0.916); LRO1 (0.866); DGA1 (0.865); FAT1 (0.86); IFA38 (0.823); ARE2 (0.788); HFD1 (0.771); PIS1 (0.756); YEH1 (0.754); PGS1 (0.747); YJU3 (0.738); ERG6 (0.724)
Homologues (species, bitscore): HSD17B1 (Homo sapiens, 74.3); Rdh8 (Mus musculus, 76.6); hsd17b1 (Danio rerio, 80.5); rdh8 (Xenopus tropicalis, 78.6); CG7322 (Drosophila melanogaster, 82.0); T25G12.13 (Caenorhabditis elegans, 84.3); AT5G10050 (Arabidopsis thaliana, 132.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:127415-128308:+ | gene-YIL124W_AKU4011 | rna-NM_001179472.3_AKU4011 | cds-NP_012142.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000174.1:9451-10344:- | gene-YIL124W_BG1 | rna-NM_001179472.3_BG1 | cds-NP_012142.3_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:130166-131059:+ | gene-YIL124W_Bruggeman | rna-NM_001179472.3_Bruggeman | cds-NP_012142.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:124045-124938:+ | gene-YIL124W_CAT1 | rna-NM_001179472.3_CAT1 | cds-NP_012142.3_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:127646-128539:+ | gene-YIL124W_CBS1585 | rna-NM_001179472.3_CBS1585 | cds-NP_012142.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:118785-119678:+ | gene-YIL124W_CBS436 | rna-NM_001179472.3_CBS436 | cds-NP_012142.3_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:125134-126027:+ | gene-YIL124W_CBS6412 | rna-NM_001179472.3_CBS6412 | cds-NP_012142.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:118894-119787:+ | gene-YIL124W_CBS6413 | rna-NM_001179472.3_CBS6413 | cds-NP_012142.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:117904-118797:+ | gene-YIL124W_CENPK1137D | rna-NM_001179472.3_CENPK1137D | cds-NP_012142.3_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:112699-113592:+ | gene-YIL124W_EthanolRed | rna-NM_001179472.3_EthanolRed | cds-NP_012142.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:128750-129643:+ | gene-YIL124W_FaliES1 | rna-NM_001179472.3_FaliES1 | cds-NP_012142.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000383.1:19690-20583:- | gene-YIL124W_JAY291 | rna-NM_001179472.3_JAY291 | cds-NP_012142.3_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:128021-128914:+ | gene-YIL124W_MUCL30387 | rna-NM_001179472.3_MUCL30387 | cds-NP_012142.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:127605-128498:+ | gene-YIL124W_MUCL30388 | rna-NM_001179472.3_MUCL30388 | cds-NP_012142.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:128592-129485:+ | gene-YIL124W_MUCL39482 | rna-NM_001179472.3_MUCL39482 | cds-NP_012142.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:131779-132672:+ | gene-YIL124W_MUCL42920 | rna-NM_001179472.3_MUCL42920 | cds-NP_012142.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:126204-127097:+ | gene-YIL124W_NCIM3186 | rna-NM_001179472.3_NCIM3186 | cds-NP_012142.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:132578-133471:+ | gene-YIL124W_NCYC1407 | rna-NM_001179472.3_NCYC1407 | cds-NP_012142.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:127258-128151:+ | gene-YIL124W_PE2H3 | rna-NM_001179472.3_PE2H3 | cds-NP_012142.3_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:121233-122126:+ | gene-YIL124W_PE2H4 | rna-NM_001179472.3_PE2H4 | cds-NP_012142.3_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:126204-127097:+ | gene-YIL124W_S288C | rna-NM_001179472.3_S288C | cds-NP_012142.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000058.1:56169-57062:- | gene-YIL124W_SA1 | rna-NM_001179472.3_SA1 | cds-NP_012142.3_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:127407-128300:+ | gene-YIL124W_ThermosaccDry | rna-NM_001179472.3_ThermosaccDry | cds-NP_012142.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:124567-125460:+ | gene-YIL124W_VR1 | rna-NM_001179472.3_VR1 | cds-NP_012142.3_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:102343-103236:+ | gene-YIL124W_ZTW1 | rna-NM_001179472.3_ZTW1 | cds-NP_012142.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:120138-121031:+ | gene-YIL124W_Sparadoxus | rna-NM_001179472.3_Sparadoxus | cds-NP_012142.3_Sparadoxus | 88.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |