Gene name: AUS1
Reference locus (S288C): YOR011W
Gene biotype: protein_coding
Description: Atp-binding cassette, subfamily g (white), member 2, snq2; ATP-dependent permease AUS1; Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen; AUS1 has a paralog, PDR11, that arose from the whole genome duplication
Top 10 interactors (score): TIR4 (0.948); DAN1 (0.866); UPC2 (0.843); NPC2 (0.813); TIR3 (0.785); YOR1 (0.736); URN1 (0.698); YBT1 (0.697); ARE2 (0.692); PDR11 (0.683); NFT1 (0.644); PAU24 (0.628); YCF1 (0.607); DET1 (0.573); ECM22 (0.571); HEM13 (0.571); HES1 (0.567); WWM1 (0.563); PAU7 (0.562); VMR1 (0.558)
Homologues (species, bitscore): ABCG2 (Homo sapiens, 170.6); Abcg2 (Mus musculus, 166.4); abcg2a (Danio rerio, 166.8); abcg2 (Xenopus tropicalis, 180.3); CG9664 (Drosophila melanogaster, 176.8); wht-8 (Caenorhabditis elegans, 152.1); ABCG31 (Arabidopsis thaliana, 347.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:333899-338083:+ | gene-YOR011W_AKU4011 | rna-NM_001183430.1_AKU4011 | cds-NP_014654.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:149476-153660:+ | gene-YOR011W_BG1 | rna-NM_001183430.1_BG1 | cds-NP_014654.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:336636-340820:+ | gene-YOR011W_Bruggeman | rna-NM_001183430.1_Bruggeman | cds-NP_014654.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:334762-338946:+ | gene-YOR011W_CAT1 | rna-NM_001183430.1_CAT1 | cds-NP_014654.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:328589-332773:+ | gene-YOR011W_CBS1585 | rna-NM_001183430.1_CBS1585 | cds-NP_014654.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:332947-337131:+ | gene-YOR011W_CBS436 | rna-NM_001183430.1_CBS436 | cds-NP_014654.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:327942-332126:+ | gene-YOR011W_CBS6412 | rna-NM_001183430.1_CBS6412 | cds-NP_014654.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:335315-339499:+ | gene-YOR011W_CBS6413 | rna-NM_001183430.1_CBS6413 | cds-NP_014654.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:349435-353619:+ | gene-YOR011W_CENPK1137D | rna-NM_001183430.1_CENPK1137D | cds-NP_014654.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:330598-334782:+ | gene-YOR011W_EthanolRed | rna-NM_001183430.1_EthanolRed | cds-NP_014654.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:333947-338131:+ | gene-YOR011W_FaliES1 | rna-NM_001183430.1_FaliES1 | cds-NP_014654.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000035.1:4593-8777:+ | gene-YOR011W_JAY291 | rna-NM_001183430.1_JAY291 | cds-NP_014654.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:341027-345211:+ | gene-YOR011W_MUCL30387 | rna-NM_001183430.1_MUCL30387 | cds-NP_014654.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:344462-348646:+ | gene-YOR011W_MUCL30388 | rna-NM_001183430.1_MUCL30388 | cds-NP_014654.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:336072-340256:+ | gene-YOR011W_MUCL39482 | rna-NM_001183430.1_MUCL39482 | cds-NP_014654.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:350876-355060:+ | gene-YOR011W_MUCL42920 | rna-NM_001183430.1_MUCL42920 | cds-NP_014654.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:349568-353752:+ | gene-YOR011W_NCIM3186 | rna-NM_001183430.1_NCIM3186 | cds-NP_014654.1_NCIM3186 | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:342772-346956:+ | gene-YOR011W_NCYC1407 | rna-NM_001183430.1_NCYC1407 | cds-NP_014654.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:341612-345796:+ | gene-YOR011W_PE2H3 | rna-NM_001183430.1_PE2H3 | cds-NP_014654.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:351991-356175:+ | gene-YOR011W_PE2H4 | rna-NM_001183430.1_PE2H4 | cds-NP_014654.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:349679-353863:+ | gene-YOR011W_S288C | rna-NM_001183430.1_S288C | cds-NP_014654.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:317446-321630:+ | gene-YOR011W_SA1 | rna-NM_001183430.1_SA1 | cds-NP_014654.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:332486-336670:+ | gene-YOR011W_ThermosaccDry | rna-NM_001183430.1_ThermosaccDry | cds-NP_014654.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:333384-337568:+ | gene-YOR011W_VR1 | rna-NM_001183430.1_VR1 | cds-NP_014654.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:67113-71297:+ | gene-YOR011W_ZTW1 | rna-NM_001183430.1_ZTW1 | cds-NP_014654.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:340977-345161:+ | gene-YOR011W_Sparadoxus | rna-NM_001183430.1_Sparadoxus | cds-NP_014654.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |