Gene name: ATX1
Reference locus (S288C): YNL259C
Gene biotype: protein_coding
Description: Metal homeostasis factor ATX1; Cytosolic copper metallochaperone; transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake; human homolog ATOX1 can complement yeast atx1 mutant; overexpression of human ATOX1 suppresses lysine auxotrophy of the yeast sod1 null mutant, as does overexpression of yeast ATX1
Top 10 interactors (score): CCC2 (0.999); COX17 (0.998); FPR2 (0.964); CIR1 (0.963); AIM45 (0.962); SOD1 (0.954); COX11 (0.934); YGR021W (0.908); FET3 (0.904); CTR2 (0.903); FTR1 (0.902); YNL011C (0.896); CTR3 (0.896); PCA1 (0.889); CCS1 (0.888); ATX2 (0.81); SCO1 (0.805); SMF3 (0.787); BSD2 (0.782); TKL1 (0.78)
Homologues (species, bitscore): atox1 (Danio rerio, 50.1); atox1 (Xenopus tropicalis, 50.8); Atox1 (Drosophila melanogaster, 59.7); cuc-1 (Caenorhabditis elegans, 58.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:151413-151634:- | gene-YNL259C_AKU4011 | rna-NM_001183097.1_AKU4011 | cds-NP_014140.1_AKU4011 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:55372-55593:- | gene-YNL259C_BG1 | rna-NM_001183097.1_BG1 | cds-NP_014140.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:161236-161457:- | gene-YNL259C_Bruggeman | rna-NM_001183097.1_Bruggeman | cds-NP_014140.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:168532-168753:- | gene-YNL259C_CAT1 | rna-NM_001183097.1_CAT1 | cds-NP_014140.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:151813-152034:- | gene-YNL259C_CBS1585 | rna-NM_001183097.1_CBS1585 | cds-NP_014140.1_CBS1585 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:146916-147137:- | gene-YNL259C_CBS436 | rna-NM_001183097.1_CBS436 | cds-NP_014140.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:148224-148445:- | gene-YNL259C_CBS6412 | rna-NM_001183097.1_CBS6412 | cds-NP_014140.1_CBS6412 | 98.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:148506-148727:- | gene-YNL259C_CBS6413 | rna-NM_001183097.1_CBS6413 | cds-NP_014140.1_CBS6413 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:151457-151678:- | gene-YNL259C_CENPK1137D | rna-NM_001183097.1_CENPK1137D | cds-NP_014140.1_CENPK1137D | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:149064-149285:- | gene-YNL259C_EthanolRed | rna-NM_001183097.1_EthanolRed | cds-NP_014140.1_EthanolRed | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:143799-144020:- | gene-YNL259C_FaliES1 | rna-NM_001183097.1_FaliES1 | cds-NP_014140.1_FaliES1 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:54970-55191:- | gene-YNL259C_JAY291 | rna-NM_001183097.1_JAY291 | cds-NP_014140.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:157020-157241:- | gene-YNL259C_MUCL30387 | rna-NM_001183097.1_MUCL30387 | cds-NP_014140.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:155605-155826:- | gene-YNL259C_MUCL30388 | rna-NM_001183097.1_MUCL30388 | cds-NP_014140.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:149303-149524:- | gene-YNL259C_MUCL39482 | rna-NM_001183097.1_MUCL39482 | cds-NP_014140.1_MUCL39482 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:151571-151792:- | gene-YNL259C_MUCL42920 | rna-NM_001183097.1_MUCL42920 | cds-NP_014140.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:157613-157834:- | gene-YNL259C_NCIM3186 | rna-NM_001183097.1_NCIM3186 | cds-NP_014140.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:151408-151629:- | gene-YNL259C_NCYC1407 | rna-NM_001183097.1_NCYC1407 | cds-NP_014140.1_NCYC1407 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:148310-148531:- | gene-YNL259C_PE2H3 | rna-NM_001183097.1_PE2H3 | cds-NP_014140.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:147698-147919:- | gene-YNL259C_PE2H4 | rna-NM_001183097.1_PE2H4 | cds-NP_014140.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:157644-157865:- | gene-YNL259C_S288C | rna-NM_001183097.1_S288C | cds-NP_014140.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:94425-94646:+ | gene-YNL259C_SA1 | rna-NM_001183097.1_SA1 | cds-NP_014140.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:144655-144876:- | gene-YNL259C_ThermosaccDry | rna-NM_001183097.1_ThermosaccDry | cds-NP_014140.1_ThermosaccDry | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:163568-163789:- | gene-YNL259C_VR1 | rna-NM_001183097.1_VR1 | cds-NP_014140.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:54987-55208:- | gene-YNL259C_ZTW1 | rna-NM_001183097.1_ZTW1 | cds-NP_014140.1_ZTW1 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:154846-155067:- | gene-YNL259C_Sparadoxus | rna-NM_001183097.1_Sparadoxus | cds-NP_014140.1_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |