Gene name: ATP6
Reference locus (S288C): Q0085
Gene biotype: protein_coding
Description: Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase; mitochondrially encoded; translation is specifically activated by Atp22p; ATP6 and ATP8 mRNAs are not translated in the absence of the F1 sector of ATPase; mutations in human ortholog MT-ATP6 are associated with neurodegenerative disorders such as Neurogenic Ataxia and Retinitis Pigmentosa (NARP), Leigh syndrome (LS), Charcot-Marie-Tooth (CMT), and ataxia telangiectasia
Top 10 interactors (score): ATP3 (0.999); ATP4 (0.999); ATP16 (0.999); ATP8 (0.999); COX1 (0.999); ATP2 (0.999); ATP15 (0.999); ATP5 (0.999); OLI1 (0.999); COB (0.999); ATP1 (0.999); ATP7 (0.999); COX3 (0.998); COX2 (0.998); VMA3 (0.992); VMA11 (0.992); ATP14 (0.991); AI5_ALPHA (0.991); ATP18 (0.989); AI4 (0.987)
Homologues (species, bitscore): MT-ATP6 (Homo sapiens, 116.3); mt-Atp6 (Mus musculus, 109.4); ATP6 (Danio rerio, 101.3); ATP6 (Xenopus tropicalis, 100.5); mt:ATPase6 (Drosophila melanogaster, 93.2); ATPase (Arabidopsis thaliana, 172.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | MBVO01000055.1:21643-22422:+ | gene-Q0085_AKU4011 | rna-Q0085_AKU4011 | cds-NP_009313.1_AKU4011 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | MBVY01000150.1:91-870:+ | gene-Q0085_Bruggeman | rna-Q0085_Bruggeman | cds-NP_009313.1_Bruggeman | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | MBWC01000027.1:1899-2678:- | gene-Q0085_CAT1 | rna-Q0085_CAT1 | cds-NP_009313.1_CAT1 | 97.6 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | MBVS01000067.1:21036-21815:+ | gene-Q0085_CBS1585 | rna-Q0085_CBS1585 | cds-NP_009313.1_CBS1585 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | MBVR01000053.1:26957-27736:+ | gene-Q0085_CBS436 | rna-Q0085_CBS436 | cds-NP_009313.1_CBS436 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | MBVQ01000062.1:16263-17042:+ | gene-Q0085_CBS6412 | rna-Q0085_CBS6412 | cds-NP_009313.1_CBS6412 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | MBVP01000101.1:52109-52888:+ | gene-Q0085_CBS6413 | rna-Q0085_CBS6413 | cds-NP_009313.1_CBS6413 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | MBWB01000074.1:15218-15997:+ | gene-Q0085_EthanolRed | rna-Q0085_EthanolRed | cds-NP_009313.1_EthanolRed | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | MBWD01000016.1:21425-22204:+ | gene-Q0085_FaliES1 | rna-Q0085_FaliES1 | cds-NP_009313.1_FaliES1 | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000183.1:1265-2044:- | gene-Q0085_JAY291 | rna-Q0085_JAY291 | cds-NP_009313.1_JAY291 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | MBVX01000280.1:1914-2693:- | gene-Q0085_MUCL30387 | rna-Q0085_MUCL30387 | cds-NP_009313.1_MUCL30387 | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | MBVW01000103.1:143-922:+ | gene-Q0085_MUCL30388 | rna-Q0085_MUCL30388 | cds-NP_009313.1_MUCL30388 | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | MBVN01000090.1:14981-15760:+ | gene-Q0085_MUCL39482 | rna-Q0085_MUCL39482 | cds-NP_009313.1_MUCL39482 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000309.1:23483-24262:+ | gene-Q0085_MUCL42920 | rna-Q0085_MUCL42920 | cds-NP_009313.1_MUCL42920 | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011826.1:28487-29266:+ | gene-Q0085_NCIM3186 | rna-Q0085_NCIM3186 | cds-NP_009313.1_NCIM3186 | 99.3 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | MBVM01000104.1:1921-2700:- | gene-Q0085_NCYC1407 | rna-Q0085_NCYC1407 | cds-NP_009313.1_NCYC1407 | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994156.1:23387-24166:+ | gene-Q0085_PE2H3 | rna-Q0085_PE2H3 | cds-NP_009313.1_PE2H3 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999888.1:23387-24166:+ | gene-Q0085_PE2H4 | rna-Q0085_PE2H4 | cds-NP_009313.1_PE2H4 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001224.1:28487-29266:+ | gene-Q0085_S288C | rna-Q0085_S288C | cds-NP_009313.1_S288C | 100.0 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000049.1:84949-85444:- | gene-Q0085_SA1 | rna-Q0085_SA1 | cds-NP_009313.1_SA1 | 61.7 | 63.5 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | MBWA01000001.1:1895-2674:- | gene-Q0085_ThermosaccDry | rna-Q0085_ThermosaccDry | cds-NP_009313.1_ThermosaccDry | 97.5 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | MBVZ01000063.1:782-1561:- | gene-Q0085_VR1 | rna-Q0085_VR1 | cds-NP_009313.1_VR1 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_018044.1:32390-33169:+ | gene-Q0085_Sparadoxus | rna-Q0085_Sparadoxus | cds-NP_009313.1_Sparadoxus | 97.4 | 100.0 | Unannotated | 1 | 1 | 0 | Unknown | False | False | False | False |