ATP12 (YJL180C)


Gene profile

Gene name: ATP12
Reference locus (S288C): YJL180C
Gene biotype: protein_coding

Description: Protein ATP12, mitochondrial; Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase; conserved protein; required for assembly of alpha and beta subunits into F1 sector of mitochondrial F1F0 ATP synthase; human homolog ATPAF2 can complement yeast atp12 mutant; mutation of human homolog reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency

Top 10 interactors (score): ATP11 (0.998); ATP2 (0.972); ATP1 (0.969); FMC1 (0.961); MRPL17 (0.947); ATP23 (0.92); MRPL8 (0.917); ATG5 (0.909); ACP1 (0.907); ATP6 (0.906); ATG4 (0.904); ATG10 (0.904); ATG3 (0.903); ATG7 (0.903); ATG16 (0.902); ATP10 (0.861); ATG8 (0.858); ATG12 (0.856); ATP4 (0.823); SHY1 (0.818)

Homologues (species, bitscore): ATPAF2 (Homo sapiens, 55.1); Atpaf2 (Mus musculus, 55.1); atpaf2 (Danio rerio, 61.6); atpaf2 (Xenopus tropicalis, 58.5); Y116A8C.27 (Caenorhabditis elegans, 53.1); AT5G40660 (Arabidopsis thaliana, 52.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:75977-76954:- gene-YJL180C_AKU4011 rna-NM_001181613.1_AKU4011 cds-NP_012355.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000181.1:53303-54280:- gene-YJL180C_BG1 rna-NM_001181613.1_BG1 cds-NP_012355.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:87805-88782:- gene-YJL180C_Bruggeman rna-NM_001181613.1_Bruggeman cds-NP_012355.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:91274-92251:- gene-YJL180C_CAT1 rna-NM_001181613.1_CAT1 cds-NP_012355.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:81612-82589:- gene-YJL180C_CBS1585 rna-NM_001181613.1_CBS1585 cds-NP_012355.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:106370-107347:- gene-YJL180C_CBS436 rna-NM_001181613.1_CBS436 cds-NP_012355.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:78094-79071:- gene-YJL180C_CBS6412 rna-NM_001181613.1_CBS6412 cds-NP_012355.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:79087-80064:- gene-YJL180C_CBS6413 rna-NM_001181613.1_CBS6413 cds-NP_012355.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:70058-71035:- gene-YJL180C_CENPK1137D rna-NM_001181613.1_CENPK1137D cds-NP_012355.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:80273-81250:- gene-YJL180C_EthanolRed rna-NM_001181613.1_EthanolRed cds-NP_012355.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:85550-86527:- gene-YJL180C_FaliES1 rna-NM_001181613.1_FaliES1 cds-NP_012355.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000164.1:32208-33185:+ gene-YJL180C_JAY291 rna-NM_001181613.1_JAY291 cds-NP_012355.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:89533-90510:- gene-YJL180C_MUCL30387 rna-NM_001181613.1_MUCL30387 cds-NP_012355.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:85694-86671:- gene-YJL180C_MUCL30388 rna-NM_001181613.1_MUCL30388 cds-NP_012355.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:80353-81330:- gene-YJL180C_MUCL39482 rna-NM_001181613.1_MUCL39482 cds-NP_012355.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:84961-85938:- gene-YJL180C_MUCL42920 rna-NM_001181613.1_MUCL42920 cds-NP_012355.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:87562-88539:- gene-YJL180C_NCIM3186 rna-NM_001181613.1_NCIM3186 cds-NP_012355.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:78965-79942:- gene-YJL180C_NCYC1407 rna-NM_001181613.1_NCYC1407 cds-NP_012355.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:91668-92645:- gene-YJL180C_PE2H3 rna-NM_001181613.1_PE2H3 cds-NP_012355.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:91307-92284:- gene-YJL180C_PE2H4 rna-NM_001181613.1_PE2H4 cds-NP_012355.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:87583-88560:- gene-YJL180C_S288C rna-NM_001181613.1_S288C cds-NP_012355.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000022.1:65313-66290:+ gene-YJL180C_SA1 rna-NM_001181613.1_SA1 cds-NP_012355.1_SA1 99.1 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:78744-79721:- gene-YJL180C_ThermosaccDry rna-NM_001181613.1_ThermosaccDry cds-NP_012355.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:85626-86603:- gene-YJL180C_VR1 rna-NM_001181613.1_VR1 cds-NP_012355.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:66330-67307:- gene-YJL180C_ZTW1 rna-NM_001181613.1_ZTW1 cds-NP_012355.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:90748-91725:- gene-YJL180C_Sparadoxus rna-NM_001181613.1_Sparadoxus cds-NP_012355.1_Sparadoxus 86.9 99.8 Verified 1 1 1 False True False False False

Additional files