Gene name: ATG8
Reference locus (S288C): YBL078C
Gene biotype: protein_coding
Description: Autophagy-related protein 8; Component of autophagosomes and Cvt vesicles; regulator of Atg1p, targets it to autophagosomes; binds the Atg1p-Atg13p complex, triggering its vacuolar degradation; unique ubiquitin-like protein whose conjugation target is lipid phosphatidylethanolamine (PE); Atg8p-PE is anchored to membranes, is involved in phagophore expansion, and may mediate membrane fusion during autophagosome formation; deconjugation of Atg8p-PE is required for efficient autophagosome biogenesis
Top 10 interactors (score): ATG12 (0.999); ATG5 (0.999); VPS30 (0.999); ATG7 (0.999); VPS34 (0.999); ATG19 (0.999); ATG1 (0.999); ATG18 (0.999); ATG3 (0.999); ATG32 (0.999); ATG4 (0.999); ATG11 (0.998); ATG9 (0.997); VPS15 (0.997); DSK2 (0.996); ATG2 (0.991); ATG36 (0.989); APE1 (0.988); YKR051W (0.988); BPH1 (0.985)
Homologues (species, bitscore): GABARAPL1 (Homo sapiens, 142.9); Gabarapl1 (Mus musculus, 142.9); gabarapl2 (Danio rerio, 144.1); gabarapl2 (Xenopus tropicalis, 143.3); Atg8a (Drosophila melanogaster, 144.8); lgg-1 (Caenorhabditis elegans, 135.6); ATG8C (Arabidopsis thaliana, 179.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:73932-74285:- | gene-YBL078C_AKU4011 | rna-NM_001178318.1_AKU4011 | cds-NP_009475.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:64822-65175:- | gene-YBL078C_BG1 | rna-NM_001178318.1_BG1 | cds-NP_009475.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:74541-74894:- | gene-YBL078C_Bruggeman | rna-NM_001178318.1_Bruggeman | cds-NP_009475.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:76497-76850:- | gene-YBL078C_CAT1 | rna-NM_001178318.1_CAT1 | cds-NP_009475.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:66031-66384:- | gene-YBL078C_CBS1585 | rna-NM_001178318.1_CBS1585 | cds-NP_009475.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:74787-75140:- | gene-YBL078C_CBS436 | rna-NM_001178318.1_CBS436 | cds-NP_009475.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:65424-65777:- | gene-YBL078C_CBS6412 | rna-NM_001178318.1_CBS6412 | cds-NP_009475.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:72079-72432:- | gene-YBL078C_CBS6413 | rna-NM_001178318.1_CBS6413 | cds-NP_009475.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:74031-74384:- | gene-YBL078C_CENPK1137D | rna-NM_001178318.1_CENPK1137D | cds-NP_009475.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:88185-88538:- | gene-YBL078C_EthanolRed | rna-NM_001178318.1_EthanolRed | cds-NP_009475.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:88314-88667:- | gene-YBL078C_FaliES1 | rna-NM_001178318.1_FaliES1 | cds-NP_009475.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000019.1:20196-20549:- | gene-YBL078C_JAY291 | rna-NM_001178318.1_JAY291 | cds-NP_009475.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:73674-74027:- | gene-YBL078C_MUCL30387 | rna-NM_001178318.1_MUCL30387 | cds-NP_009475.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:75197-75550:- | gene-YBL078C_MUCL30388 | rna-NM_001178318.1_MUCL30388 | cds-NP_009475.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:66212-66565:- | gene-YBL078C_MUCL39482 | rna-NM_001178318.1_MUCL39482 | cds-NP_009475.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:73045-73398:- | gene-YBL078C_MUCL42920 | rna-NM_001178318.1_MUCL42920 | cds-NP_009475.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:80175-80528:- | gene-YBL078C_NCIM3186 | rna-NM_001178318.1_NCIM3186 | cds-NP_009475.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:67823-68176:- | gene-YBL078C_NCYC1407 | rna-NM_001178318.1_NCYC1407 | cds-NP_009475.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:74111-74464:- | gene-YBL078C_PE2H3 | rna-NM_001178318.1_PE2H3 | cds-NP_009475.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:71755-72108:- | gene-YBL078C_PE2H4 | rna-NM_001178318.1_PE2H4 | cds-NP_009475.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:80378-80731:- | gene-YBL078C_S288C | rna-NM_001178318.1_S288C | cds-NP_009475.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:64489-64842:- | gene-YBL078C_SA1 | rna-NM_001178318.1_SA1 | cds-NP_009475.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:88275-88628:- | gene-YBL078C_ThermosaccDry | rna-NM_001178318.1_ThermosaccDry | cds-NP_009475.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:70445-70798:- | gene-YBL078C_VR1 | rna-NM_001178318.1_VR1 | cds-NP_009475.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:65491-65844:- | gene-YBL078C_ZTW1 | rna-NM_001178318.1_ZTW1 | cds-NP_009475.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:100203-100556:- | gene-YBL078C_Sparadoxus | rna-NM_001178318.1_Sparadoxus | cds-NP_009475.1_Sparadoxus | 92.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |