Gene name: ATG7
Reference locus (S288C): YHR171W
Gene biotype: protein_coding
Description: Ubiquitin-like modifier-activating enzyme ATG7; Autophagy-related protein and dual specificity member of the E1 family; mediates the attachment of Atg12p to Atg5p and Atg8p to phosphatidylethanolamine which are required steps in autophagosome formation; E1 enzymes are also known as ubiquitin-activating enzymes; involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner; Belongs to the ATG7 family
Top 10 interactors (score): ATG8 (0.999); ATG3 (0.999); ATG12 (0.999); ATG10 (0.999); ATG18 (0.999); ATG5 (0.998); ATG9 (0.998); ATG1 (0.998); ATG4 (0.998); VPS30 (0.997); VPS34 (0.994); ATG2 (0.991); VPS15 (0.991); ATG11 (0.975); ATG13 (0.973); ATG15 (0.96); ATG21 (0.96); ATG16 (0.945); YPT7 (0.921); SNX4 (0.915)
Homologues (species, bitscore): ATG7 (Homo sapiens, 423.3); Atg7 (Mus musculus, 427.6); ATG7 (Danio rerio, 391.7); ATG7 (Xenopus tropicalis, 252.7); Atg7 (Drosophila melanogaster, 396.7); atg-7 (Caenorhabditis elegans, 404.1); APG7 (Arabidopsis thaliana, 439.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:432809-434701:+ | gene-YHR171W_AKU4011 | rna-NM_001179302.1_AKU4011 | cds-NP_012041.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:83039-84931:- | gene-YHR171W_BG1 | rna-NM_001179302.1_BG1 | cds-NP_012041.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:440050-441942:+ | gene-YHR171W_Bruggeman | rna-NM_001179302.1_Bruggeman | cds-NP_012041.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:435453-437345:+ | gene-YHR171W_CAT1 | rna-NM_001179302.1_CAT1 | cds-NP_012041.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:432263-434155:+ | gene-YHR171W_CBS1585 | rna-NM_001179302.1_CBS1585 | cds-NP_012041.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:429705-431597:+ | gene-YHR171W_CBS436 | rna-NM_001179302.1_CBS436 | cds-NP_012041.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:432721-434613:+ | gene-YHR171W_CBS6412 | rna-NM_001179302.1_CBS6412 | cds-NP_012041.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:433148-435040:+ | gene-YHR171W_CBS6413 | rna-NM_001179302.1_CBS6413 | cds-NP_012041.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:438884-440776:+ | gene-YHR171W_CENPK1137D | rna-NM_001179302.1_CENPK1137D | cds-NP_012041.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:491358-493250:+ | gene-YHR171W_EthanolRed | rna-NM_001179302.1_EthanolRed | cds-NP_012041.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:433801-435693:+ | gene-YHR171W_FaliES1 | rna-NM_001179302.1_FaliES1 | cds-NP_012041.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000017.1:4152-6044:- | gene-YHR171W_JAY291 | rna-NM_001179302.1_JAY291 | cds-NP_012041.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:441123-443015:+ | gene-YHR171W_MUCL30387 | rna-NM_001179302.1_MUCL30387 | cds-NP_012041.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:440562-442454:+ | gene-YHR171W_MUCL30388 | rna-NM_001179302.1_MUCL30388 | cds-NP_012041.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:432174-434066:+ | gene-YHR171W_MUCL39482 | rna-NM_001179302.1_MUCL39482 | cds-NP_012041.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:438781-440673:+ | gene-YHR171W_MUCL42920 | rna-NM_001179302.1_MUCL42920 | cds-NP_012041.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:445595-447487:+ | gene-YHR171W_NCIM3186 | rna-NM_001179302.1_NCIM3186 | cds-NP_012041.1_NCIM3186 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:434633-436525:+ | gene-YHR171W_NCYC1407 | rna-NM_001179302.1_NCYC1407 | cds-NP_012041.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:433774-435666:+ | gene-YHR171W_PE2H3 | rna-NM_001179302.1_PE2H3 | cds-NP_012041.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:441201-443093:+ | gene-YHR171W_PE2H4 | rna-NM_001179302.1_PE2H4 | cds-NP_012041.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:445713-447605:+ | gene-YHR171W_S288C | rna-NM_001179302.1_S288C | cds-NP_012041.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000070.1:4211-6103:- | gene-YHR171W_SA1 | rna-NM_001179302.1_SA1 | cds-NP_012041.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:434884-436776:+ | gene-YHR171W_ThermosaccDry | rna-NM_001179302.1_ThermosaccDry | cds-NP_012041.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:442700-444592:+ | gene-YHR171W_VR1 | rna-NM_001179302.1_VR1 | cds-NP_012041.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:425125-427017:+ | gene-YHR171W_ZTW1 | rna-NM_001179302.1_ZTW1 | cds-NP_012041.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:431254-433146:+ | gene-YHR171W_Sparadoxus | rna-NM_001179302.1_Sparadoxus | cds-NP_012041.1_Sparadoxus | 87.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |