Gene name: ATG4
Reference locus (S288C): YNL223W
Gene biotype: protein_coding
Description: Cysteine protease atg4; Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation
Top 10 interactors (score): ATG1 (0.999); ATG3 (0.999); ATG8 (0.999); ATG7 (0.998); VPS30 (0.997); ATG2 (0.996); ATG12 (0.996); ATG5 (0.996); ATG18 (0.996); ATG9 (0.993); VPS34 (0.992); VPS15 (0.981); ATG10 (0.958); ATG13 (0.957); ATG21 (0.957); ATG16 (0.942); ATG29 (0.936); ATG11 (0.935); ATG23 (0.906); ATP12 (0.904)
Homologues (species, bitscore): ATG4B (Homo sapiens, 131.3); Atg4d (Mus musculus, 129.4); atg4a (Danio rerio, 131.3); atg4b (Xenopus tropicalis, 130.6); Atg4a (Drosophila melanogaster, 126.3); atg-4.1 (Caenorhabditis elegans, 108.6); AT3G59950 (Arabidopsis thaliana, 111.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:221150-222634:+ | gene-YNL223W_AKU4011 | rna-NM_001183061.1_AKU4011 | cds-NP_014176.2_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:125093-126577:+ | gene-YNL223W_BG1 | rna-NM_001183061.1_BG1 | cds-NP_014176.2_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:231199-232683:+ | gene-YNL223W_Bruggeman | rna-NM_001183061.1_Bruggeman | cds-NP_014176.2_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:238355-239839:+ | gene-YNL223W_CAT1 | rna-NM_001183061.1_CAT1 | cds-NP_014176.2_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:221547-223031:+ | gene-YNL223W_CBS1585 | rna-NM_001183061.1_CBS1585 | cds-NP_014176.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:216630-218114:+ | gene-YNL223W_CBS436 | rna-NM_001183061.1_CBS436 | cds-NP_014176.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:217581-219065:+ | gene-YNL223W_CBS6412 | rna-NM_001183061.1_CBS6412 | cds-NP_014176.2_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:218229-219713:+ | gene-YNL223W_CBS6413 | rna-NM_001183061.1_CBS6413 | cds-NP_014176.2_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:221173-222657:+ | gene-YNL223W_CENPK1137D | rna-NM_001183061.1_CENPK1137D | cds-NP_014176.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:218785-220269:+ | gene-YNL223W_EthanolRed | rna-NM_001183061.1_EthanolRed | cds-NP_014176.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:213527-215011:+ | gene-YNL223W_FaliES1 | rna-NM_001183061.1_FaliES1 | cds-NP_014176.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:124683-126167:+ | gene-YNL223W_JAY291 | rna-NM_001183061.1_JAY291 | cds-NP_014176.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:226735-228219:+ | gene-YNL223W_MUCL30387 | rna-NM_001183061.1_MUCL30387 | cds-NP_014176.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:225318-226802:+ | gene-YNL223W_MUCL30388 | rna-NM_001183061.1_MUCL30388 | cds-NP_014176.2_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:219037-220521:+ | gene-YNL223W_MUCL39482 | rna-NM_001183061.1_MUCL39482 | cds-NP_014176.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:221291-222775:+ | gene-YNL223W_MUCL42920 | rna-NM_001183061.1_MUCL42920 | cds-NP_014176.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:227339-228823:+ | gene-YNL223W_NCIM3186 | rna-NM_001183061.1_NCIM3186 | cds-NP_014176.2_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:221129-222613:+ | gene-YNL223W_NCYC1407 | rna-NM_001183061.1_NCYC1407 | cds-NP_014176.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:218028-219512:+ | gene-YNL223W_PE2H3 | rna-NM_001183061.1_PE2H3 | cds-NP_014176.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:217416-218900:+ | gene-YNL223W_PE2H4 | rna-NM_001183061.1_PE2H4 | cds-NP_014176.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:227370-228854:+ | gene-YNL223W_S288C | rna-NM_001183061.1_S288C | cds-NP_014176.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:23450-24934:- | gene-YNL223W_SA1 | rna-NM_001183061.1_SA1 | cds-NP_014176.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:214383-215867:+ | gene-YNL223W_ThermosaccDry | rna-NM_001183061.1_ThermosaccDry | cds-NP_014176.2_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:233384-234868:+ | gene-YNL223W_VR1 | rna-NM_001183061.1_VR1 | cds-NP_014176.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:124715-126199:+ | gene-YNL223W_ZTW1 | rna-NM_001183061.1_ZTW1 | cds-NP_014176.2_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:224789-226273:+ | gene-YNL223W_Sparadoxus | rna-NM_001183061.1_Sparadoxus | cds-NP_014176.2_Sparadoxus | 90.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |