Gene name: ATG2
Reference locus (S288C): YNL242W
Gene biotype: protein_coding
Description: Autophagy-related protein 2; Peripheral membrane protein required for autophagic vesicle formation; also required for vesicle formation during pexophagy and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the phagophore assembly site and mitochondria; contains an APT1 domain that binds phosphatidylinositol-3-phosphate; essential for cell cycle progression from G2/M to G1 under nitrogen starvation; forms cytoplasmic foci upon DNA replication stress
Top 10 interactors (score): ATG1 (0.999); ATG18 (0.999); ATG9 (0.999); ATG4 (0.996); ATG5 (0.993); VPS30 (0.992); VPS34 (0.992); ATG12 (0.992); ATG8 (0.991); ATG3 (0.991); ATG7 (0.991); VPS15 (0.99); ATG11 (0.989); HSV2 (0.981); ATG21 (0.98); ATG13 (0.964); VPS13 (0.935); ATG31 (0.918); ATG29 (0.899); ATG16 (0.896)
Homologues (species, bitscore): ATG2B (Homo sapiens, 109.4); Atg2b (Mus musculus, 110.9); ATG2A (Xenopus tropicalis, 105.9); Atg2 (Drosophila melanogaster, 70.1); ATG2 (Arabidopsis thaliana, 94.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:185111-189889:+ | gene-YNL242W_AKU4011 | rna-NM_001183080.1_AKU4011 | cds-NP_014157.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:89051-93829:+ | gene-YNL242W_BG1 | rna-NM_001183080.1_BG1 | cds-NP_014157.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:194913-199691:+ | gene-YNL242W_Bruggeman | rna-NM_001183080.1_Bruggeman | cds-NP_014157.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:202210-206988:+ | gene-YNL242W_CAT1 | rna-NM_001183080.1_CAT1 | cds-NP_014157.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:185508-190286:+ | gene-YNL242W_CBS1585 | rna-NM_001183080.1_CBS1585 | cds-NP_014157.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:180594-185372:+ | gene-YNL242W_CBS436 | rna-NM_001183080.1_CBS436 | cds-NP_014157.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:181547-186325:+ | gene-YNL242W_CBS6412 | rna-NM_001183080.1_CBS6412 | cds-NP_014157.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:182190-186968:+ | gene-YNL242W_CBS6413 | rna-NM_001183080.1_CBS6413 | cds-NP_014157.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:185135-189913:+ | gene-YNL242W_CENPK1137D | rna-NM_001183080.1_CENPK1137D | cds-NP_014157.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:182767-187545:+ | gene-YNL242W_EthanolRed | rna-NM_001183080.1_EthanolRed | cds-NP_014157.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:177502-182280:+ | gene-YNL242W_FaliES1 | rna-NM_001183080.1_FaliES1 | cds-NP_014157.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:88644-93423:+ | gene-YNL242W_JAY291 | rna-NM_001183080.1_JAY291 | cds-NP_014157.1_JAY291 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:190698-195476:+ | gene-YNL242W_MUCL30387 | rna-NM_001183080.1_MUCL30387 | cds-NP_014157.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:189281-194059:+ | gene-YNL242W_MUCL30388 | rna-NM_001183080.1_MUCL30388 | cds-NP_014157.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:182998-187776:+ | gene-YNL242W_MUCL39482 | rna-NM_001183080.1_MUCL39482 | cds-NP_014157.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:185254-190032:+ | gene-YNL242W_MUCL42920 | rna-NM_001183080.1_MUCL42920 | cds-NP_014157.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:191293-196071:+ | gene-YNL242W_NCIM3186 | rna-NM_001183080.1_NCIM3186 | cds-NP_014157.1_NCIM3186 | 95.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:185086-189864:+ | gene-YNL242W_NCYC1407 | rna-NM_001183080.1_NCYC1407 | cds-NP_014157.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:181988-186766:+ | gene-YNL242W_PE2H3 | rna-NM_001183080.1_PE2H3 | cds-NP_014157.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:181376-186154:+ | gene-YNL242W_PE2H4 | rna-NM_001183080.1_PE2H4 | cds-NP_014157.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:191324-196102:+ | gene-YNL242W_S288C | rna-NM_001183080.1_S288C | cds-NP_014157.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:56193-60971:- | gene-YNL242W_SA1 | rna-NM_001183080.1_SA1 | cds-NP_014157.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:178358-183136:+ | gene-YNL242W_ThermosaccDry | rna-NM_001183080.1_ThermosaccDry | cds-NP_014157.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:197244-202022:+ | gene-YNL242W_VR1 | rna-NM_001183080.1_VR1 | cds-NP_014157.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:88678-93456:+ | gene-YNL242W_ZTW1 | rna-NM_001183080.1_ZTW1 | cds-NP_014157.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:188624-193402:+ | gene-YNL242W_Sparadoxus | rna-NM_001183080.1_Sparadoxus | cds-NP_014157.1_Sparadoxus | 88.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |