Gene name: ATG15
Reference locus (S288C): YCR068W
Gene biotype: protein_coding
Description: Putative lipase ATG15; Phospholipase; preferentially hydrolyses phosphatidylserine, with minor activity against cardiolipin and phosphatidylethanolamine; required for lysis of autophagic and CVT bodies; targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway; required for the maintenance of lipid droplet quantity after the diauxic shift; regulates lipolysis; expression regulated by Yap1p during autophagy; Belongs to the AB hydrolase superfamily. Lipase family
Top 10 interactors (score): ATG1 (0.974); TGL3 (0.966); ATG7 (0.96); ATG18 (0.935); ATG22 (0.934); TGL4 (0.931); ATG5 (0.925); YJU3 (0.921); ATG9 (0.919); ATG3 (0.909); DGA1 (0.908); LRO1 (0.906); ATG20 (0.906); PHM8 (0.9); ATG4 (0.9); ATG23 (0.892); ATG11 (0.891); ATG12 (0.878); ATG29 (0.869); TGL5 (0.856)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:231728-233290:+ | gene-YCR068W_AKU4011 | rna-NM_001178779.1_AKU4011 | cds-NP_009994.2_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:90404-91966:+ | gene-YCR068W_BG1 | rna-NM_001178779.1_BG1 | cds-NP_009994.2_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:227939-229501:+ | gene-YCR068W_Bruggeman | rna-NM_001178779.1_Bruggeman | cds-NP_009994.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:239009-240571:+ | gene-YCR068W_CAT1 | rna-NM_001178779.1_CAT1 | cds-NP_009994.2_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:226507-228069:+ | gene-YCR068W_CBS1585 | rna-NM_001178779.1_CBS1585 | cds-NP_009994.2_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:238344-239906:+ | gene-YCR068W_CBS436 | rna-NM_001178779.1_CBS436 | cds-NP_009994.2_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:218247-219809:+ | gene-YCR068W_CBS6412 | rna-NM_001178779.1_CBS6412 | cds-NP_009994.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:232595-234157:+ | gene-YCR068W_CBS6413 | rna-NM_001178779.1_CBS6413 | cds-NP_009994.2_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:236461-238023:+ | gene-YCR068W_CENPK1137D | rna-NM_001178779.1_CENPK1137D | cds-NP_009994.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:227700-229262:+ | gene-YCR068W_EthanolRed | rna-NM_001178779.1_EthanolRed | cds-NP_009994.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:232862-234424:+ | gene-YCR068W_FaliES1 | rna-NM_001178779.1_FaliES1 | cds-NP_009994.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000323.1:54298-55860:- | gene-YCR068W_JAY291 | rna-NM_001178779.1_JAY291 | cds-NP_009994.2_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:224664-226226:+ | gene-YCR068W_MUCL30387 | rna-NM_001178779.1_MUCL30387 | cds-NP_009994.2_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:224935-226497:+ | gene-YCR068W_MUCL30388 | rna-NM_001178779.1_MUCL30388 | cds-NP_009994.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:233080-234642:+ | gene-YCR068W_MUCL39482 | rna-NM_001178779.1_MUCL39482 | cds-NP_009994.2_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:229515-231077:+ | gene-YCR068W_MUCL42920 | rna-NM_001178779.1_MUCL42920 | cds-NP_009994.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:236846-238408:+ | gene-YCR068W_NCIM3186 | rna-NM_001178779.1_NCIM3186 | cds-NP_009994.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:233939-235501:+ | gene-YCR068W_NCYC1407 | rna-NM_001178779.1_NCYC1407 | cds-NP_009994.2_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:248526-250088:+ | gene-YCR068W_PE2H3 | rna-NM_001178779.1_PE2H3 | cds-NP_009994.2_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:237078-238640:+ | gene-YCR068W_PE2H4 | rna-NM_001178779.1_PE2H4 | cds-NP_009994.2_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:237214-238776:+ | gene-YCR068W_S288C | rna-NM_001178779.1_S288C | cds-NP_009994.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:37094-38656:+ | gene-YCR068W_SA1 | rna-NM_001178779.1_SA1 | cds-NP_009994.2_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:232789-234351:+ | gene-YCR068W_ThermosaccDry | rna-NM_001178779.1_ThermosaccDry | cds-NP_009994.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:244063-245625:+ | gene-YCR068W_VR1 | rna-NM_001178779.1_VR1 | cds-NP_009994.2_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:230662-232224:+ | gene-YCR068W_ZTW1 | rna-NM_001178779.1_ZTW1 | cds-NP_009994.2_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:264852-266411:+ | gene-YCR068W_Sparadoxus | rna-NM_001178779.1_Sparadoxus | cds-NP_009994.2_Sparadoxus | 88.9 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |