ATG1 (YGL180W)


Gene profile

Gene name: ATG1
Reference locus (S288C): YGL180W
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase ATG1; Protein serine/threonine kinase; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p; essential for cell cycle progression from G2/M to G1 under nitrogen starvation

Top 10 interactors (score): ATG13 (0.999); ATG11 (0.999); VPS30 (0.999); TOR1 (0.999); ATG9 (0.999); ATG2 (0.999); ATG17 (0.999); VPS34 (0.999); ATG4 (0.999); ATG8 (0.999); ATG18 (0.998); ATG29 (0.998); ATG7 (0.998); TOR2 (0.998); VPS15 (0.998); ATG5 (0.996); ATG12 (0.995); ATG3 (0.995); ATG31 (0.992); ATG14 (0.983)

Homologues (species, bitscore): ULK3 (Homo sapiens, 201.1); Ulk3 (Mus musculus, 202.2); ulk2 (Danio rerio, 192.2); ulk3 (Xenopus tropicalis, 192.6); Atg1 (Drosophila melanogaster, 176.8); unc-51 (Caenorhabditis elegans, 187.6); AT2G37840 (Arabidopsis thaliana, 219.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:162611-165304:+ gene-YGL180W_AKU4011 rna-NM_001181045.1_AKU4011 cds-NP_011335.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:245133-247826:- gene-YGL180W_BG1 rna-NM_001181045.1_BG1 cds-NP_011335.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:164832-167525:+ gene-YGL180W_Bruggeman rna-NM_001181045.1_Bruggeman cds-NP_011335.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:160698-163391:+ gene-YGL180W_CAT1 rna-NM_001181045.1_CAT1 cds-NP_011335.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:165756-168449:+ gene-YGL180W_CBS1585 rna-NM_001181045.1_CBS1585 cds-NP_011335.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:160728-163421:+ gene-YGL180W_CBS436 rna-NM_001181045.1_CBS436 cds-NP_011335.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:152536-155229:+ gene-YGL180W_CBS6412 rna-NM_001181045.1_CBS6412 cds-NP_011335.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:160065-162758:+ gene-YGL180W_CBS6413 rna-NM_001181045.1_CBS6413 cds-NP_011335.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:160256-162949:+ gene-YGL180W_CENPK1137D rna-NM_001181045.1_CENPK1137D cds-NP_011335.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:152429-155122:+ gene-YGL180W_EthanolRed rna-NM_001181045.1_EthanolRed cds-NP_011335.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:153676-156369:+ gene-YGL180W_FaliES1 rna-NM_001181045.1_FaliES1 cds-NP_011335.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000090.1:3923-6616:+ gene-YGL180W_JAY291 rna-NM_001181045.1_JAY291 cds-NP_011335.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:162075-164768:+ gene-YGL180W_MUCL30387 rna-NM_001181045.1_MUCL30387 cds-NP_011335.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:165167-167860:+ gene-YGL180W_MUCL30388 rna-NM_001181045.1_MUCL30388 cds-NP_011335.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:162760-165453:+ gene-YGL180W_MUCL39482 rna-NM_001181045.1_MUCL39482 cds-NP_011335.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:165382-168075:+ gene-YGL180W_MUCL42920 rna-NM_001181045.1_MUCL42920 cds-NP_011335.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:160065-162758:+ gene-YGL180W_NCIM3186 rna-NM_001181045.1_NCIM3186 cds-NP_011335.1_NCIM3186 99.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:154247-156940:+ gene-YGL180W_NCYC1407 rna-NM_001181045.1_NCYC1407 cds-NP_011335.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:156222-158915:+ gene-YGL180W_PE2H3 rna-NM_001181045.1_PE2H3 cds-NP_011335.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:155770-158463:+ gene-YGL180W_PE2H4 rna-NM_001181045.1_PE2H4 cds-NP_011335.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:160065-162758:+ gene-YGL180W_S288C rna-NM_001181045.1_S288C cds-NP_011335.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000067.1:19823-22516:+ gene-YGL180W_SA1 rna-NM_001181045.1_SA1 cds-NP_011335.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:153906-156599:+ gene-YGL180W_ThermosaccDry rna-NM_001181045.1_ThermosaccDry cds-NP_011335.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:161124-163817:+ gene-YGL180W_VR1 rna-NM_001181045.1_VR1 cds-NP_011335.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:152342-155035:+ gene-YGL180W_ZTW1 rna-NM_001181045.1_ZTW1 cds-NP_011335.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:159201-161894:+ gene-YGL180W_Sparadoxus rna-NM_001181045.1_Sparadoxus cds-NP_011335.1_Sparadoxus 90.0 100.0 Verified 1 1 1 False True False False False

Additional files