Gene name: AST2
Reference locus (S288C): YER101C
Gene biotype: protein_coding
Description: Protein AST2; Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication
Top 10 interactors (score): YGL214W (0.812); YKL077W (0.779); YDL121C (0.775); FYV8 (0.773); ETR1 (0.726); SFB3 (0.705); MSC1 (0.667); GTT1 (0.655); YDL124W (0.645); TPS1 (0.6); NEL1 (0.571); ERP4 (0.57); TLG1 (0.569); YCR102C (0.563); YNL134C (0.546); YLR460C (0.546); NTH2 (0.528); NTH1 (0.499); SEC24 (0.485); GLO1 (0.484)
Homologues (species, bitscore): RTN4IP1 (Homo sapiens, 57.0); Rtn4ip1 (Mus musculus, 55.1); rtn4ip1 (Danio rerio, 65.5); rtn4ip1 (Xenopus tropicalis, 61.6); AT3G15090 (Arabidopsis thaliana, 71.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:353888-355180:- | gene-YER101C_AKU4011 | rna-NM_001178992.1_AKU4011 | cds-NP_011027.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:69929-71221:+ | gene-YER101C_BG1 | rna-NM_001178992.1_BG1 | cds-NP_011027.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:364362-365654:- | gene-YER101C_Bruggeman | rna-NM_001178992.1_Bruggeman | cds-NP_011027.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:358649-359941:- | gene-YER101C_CAT1 | rna-NM_001178992.1_CAT1 | cds-NP_011027.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:353753-355045:- | gene-YER101C_CBS1585 | rna-NM_001178992.1_CBS1585 | cds-NP_011027.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:356241-357533:- | gene-YER101C_CBS436 | rna-NM_001178992.1_CBS436 | cds-NP_011027.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:353209-354501:- | gene-YER101C_CBS6412 | rna-NM_001178992.1_CBS6412 | cds-NP_011027.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:359199-360491:- | gene-YER101C_CBS6413 | rna-NM_001178992.1_CBS6413 | cds-NP_011027.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:358277-359569:- | gene-YER101C_CENPK1137D | rna-NM_001178992.1_CENPK1137D | cds-NP_011027.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:354230-355522:- | gene-YER101C_EthanolRed | rna-NM_001178992.1_EthanolRed | cds-NP_011027.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:354675-355967:- | gene-YER101C_FaliES1 | rna-NM_001178992.1_FaliES1 | cds-NP_011027.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000356.1:1485-2777:+ | gene-YER101C_JAY291 | rna-NM_001178992.1_JAY291 | cds-NP_011027.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:360239-361531:- | gene-YER101C_MUCL30387 | rna-NM_001178992.1_MUCL30387 | cds-NP_011027.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:355787-357079:- | gene-YER101C_MUCL30388 | rna-NM_001178992.1_MUCL30388 | cds-NP_011027.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:352777-354069:- | gene-YER101C_MUCL39482 | rna-NM_001178992.1_MUCL39482 | cds-NP_011027.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:361275-362567:- | gene-YER101C_MUCL42920 | rna-NM_001178992.1_MUCL42920 | cds-NP_011027.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:360501-361793:- | gene-YER101C_NCIM3186 | rna-NM_001178992.1_NCIM3186 | cds-NP_011027.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:357840-359132:- | gene-YER101C_NCYC1407 | rna-NM_001178992.1_NCYC1407 | cds-NP_011027.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:368878-370170:- | gene-YER101C_PE2H3 | rna-NM_001178992.1_PE2H3 | cds-NP_011027.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:358819-360111:- | gene-YER101C_PE2H4 | rna-NM_001178992.1_PE2H4 | cds-NP_011027.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:360502-361794:- | gene-YER101C_S288C | rna-NM_001178992.1_S288C | cds-NP_011027.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000023.1:70118-71410:- | gene-YER101C_SA1 | rna-NM_001178992.1_SA1 | cds-NP_011027.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:355472-356764:- | gene-YER101C_ThermosaccDry | rna-NM_001178992.1_ThermosaccDry | cds-NP_011027.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:356518-357810:- | gene-YER101C_VR1 | rna-NM_001178992.1_VR1 | cds-NP_011027.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:352636-353928:- | gene-YER101C_ZTW1 | rna-NM_001178992.1_ZTW1 | cds-NP_011027.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:356545-357839:- | gene-YER101C_Sparadoxus | rna-NM_001178992.1_Sparadoxus | cds-NP_011027.1_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |