Gene name: AST1
Reference locus (S288C): YBL069W
Gene biotype: protein_coding
Description: Putative uncharacterized protein ybl068w-a; Protein AST1; Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication
Top 10 interactors (score): PMA1 (0.772); ETR1 (0.709); PMP1 (0.699); YKL077W (0.68); YDL121C (0.674); YDL124W (0.645); MSC1 (0.644); GTT1 (0.634); SFB3 (0.618); ALF1 (0.617); TDA6 (0.604); YNL134C (0.602); TPS1 (0.6); NCE101 (0.571); YKL091C (0.569); YCR102C (0.563); YLR460C (0.557); NTH2 (0.499); PMP2 (0.499); NTH1 (0.499)
Homologues (species, bitscore): RTN4IP1 (Homo sapiens, 72.0); Rtn4ip1 (Mus musculus, 69.7); rtn4ip1 (Danio rerio, 83.2); rtn4ip1 (Xenopus tropicalis, 68.9); AT3G15090 (Arabidopsis thaliana, 77.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:84320-85609:+ | gene-YBL069W_AKU4011 | rna-NM_001178309.1_AKU4011 | cds-NP_009484.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:75180-76469:+ | gene-YBL069W_BG1 | rna-NM_001178309.1_BG1 | cds-NP_009484.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:84935-86224:+ | gene-YBL069W_Bruggeman | rna-NM_001178309.1_Bruggeman | cds-NP_009484.2_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:87574-88863:+ | gene-YBL069W_CAT1 | rna-NM_001178309.1_CAT1 | cds-NP_009484.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:76887-78176:+ | gene-YBL069W_CBS1585 | rna-NM_001178309.1_CBS1585 | cds-NP_009484.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:85395-86684:+ | gene-YBL069W_CBS436 | rna-NM_001178309.1_CBS436 | cds-NP_009484.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:75393-76682:+ | gene-YBL069W_CBS6412 | rna-NM_001178309.1_CBS6412 | cds-NP_009484.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:82465-83754:+ | gene-YBL069W_CBS6413 | rna-NM_001178309.1_CBS6413 | cds-NP_009484.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:84500-85789:+ | gene-YBL069W_CENPK1137D | rna-NM_001178309.1_CENPK1137D | cds-NP_009484.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:98317-99606:+ | gene-YBL069W_EthanolRed | rna-NM_001178309.1_EthanolRed | cds-NP_009484.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:99170-100459:+ | gene-YBL069W_FaliES1 | rna-NM_001178309.1_FaliES1 | cds-NP_009484.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000072.1:1794-3083:+ | gene-YBL069W_JAY291 | rna-NM_001178309.1_JAY291 | cds-NP_009484.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:84309-85598:+ | gene-YBL069W_MUCL30387 | rna-NM_001178309.1_MUCL30387 | cds-NP_009484.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:85588-86877:+ | gene-YBL069W_MUCL30388 | rna-NM_001178309.1_MUCL30388 | cds-NP_009484.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:77068-78357:+ | gene-YBL069W_MUCL39482 | rna-NM_001178309.1_MUCL39482 | cds-NP_009484.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:83904-85193:+ | gene-YBL069W_MUCL42920 | rna-NM_001178309.1_MUCL42920 | cds-NP_009484.2_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:90538-91827:+ | gene-YBL069W_NCIM3186 | rna-NM_001178309.1_NCIM3186 | cds-NP_009484.2_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:78210-79499:+ | gene-YBL069W_NCYC1407 | rna-NM_001178309.1_NCYC1407 | cds-NP_009484.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:84469-85758:+ | gene-YBL069W_PE2H3 | rna-NM_001178309.1_PE2H3 | cds-NP_009484.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:82113-83402:+ | gene-YBL069W_PE2H4 | rna-NM_001178309.1_PE2H4 | cds-NP_009484.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:90741-92030:+ | gene-YBL069W_S288C | rna-NM_001178309.1_S288C | cds-NP_009484.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:74848-76137:+ | gene-YBL069W_SA1 | rna-NM_001178309.1_SA1 | cds-NP_009484.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:99131-100420:+ | gene-YBL069W_ThermosaccDry | rna-NM_001178309.1_ThermosaccDry | cds-NP_009484.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:81301-82590:+ | gene-YBL069W_VR1 | rna-NM_001178309.1_VR1 | cds-NP_009484.2_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:75850-77139:+ | gene-YBL069W_ZTW1 | rna-NM_001178309.1_ZTW1 | cds-NP_009484.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:110532-111821:+ | gene-YBL069W_Sparadoxus | rna-NM_001178309.1_Sparadoxus | cds-NP_009484.2_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |