Gene name: ASP1
Reference locus (S288C): YDR321W
Gene biotype: protein_coding
Description: Cytosolic L-asparaginase, involved in asparagine catabolism; catalyzes hydrolysis of L-asparagine to aspartic acid and ammonia; important enzyme for the treatment of acute lymphoblastic leukemia; has low glutaminase activity and dependence; synthesized constitutively
Top 10 interactors (score): AAT2 (0.935); ARG1 (0.931); URA2 (0.928); AAT1 (0.915); ADE12 (0.903); ASN2 (0.898); ASN1 (0.87); ASP3-1 (0.819); HOM3 (0.807); GAD1 (0.807); NIT1 (0.8); URE2 (0.788); GLN3 (0.782); TRP5 (0.639); AMD2 (0.62); FAP1 (0.618); TRP4 (0.616); GUA1 (0.601); TEM1 (0.595); ABZ1 (0.578)
Homologues (species, bitscore): Aspg (Mus musculus, 50.8); aspg (Danio rerio, 61.2); aspg (Xenopus tropicalis, 57.0); CG8526 (Drosophila melanogaster, 63.2); C27A7.5 (Caenorhabditis elegans, 64.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1054747-1055892:+ | gene-YDR321W_AKU4011 | rna-NM_001180629.3_AKU4011 | cds-NP_010607.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:75656-76801:- | gene-YDR321W_BG1 | rna-NM_001180629.3_BG1 | cds-NP_010607.3_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1082275-1083420:+ | gene-YDR321W_Bruggeman | rna-NM_001180629.3_Bruggeman | cds-NP_010607.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1069033-1070178:+ | gene-YDR321W_CAT1 | rna-NM_001180629.3_CAT1 | cds-NP_010607.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1049191-1050336:+ | gene-YDR321W_CBS1585 | rna-NM_001180629.3_CBS1585 | cds-NP_010607.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1067573-1068718:+ | gene-YDR321W_CBS436 | rna-NM_001180629.3_CBS436 | cds-NP_010607.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1045879-1047024:+ | gene-YDR321W_CBS6412 | rna-NM_001180629.3_CBS6412 | cds-NP_010607.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1067110-1068255:+ | gene-YDR321W_CBS6413 | rna-NM_001180629.3_CBS6413 | cds-NP_010607.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1107340-1108485:+ | gene-YDR321W_CENPK1137D | rna-NM_001180629.3_CENPK1137D | cds-NP_010607.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:230287-231432:+ | gene-YDR321W_EthanolRed | rna-NM_001180629.3_EthanolRed | cds-NP_010607.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1061502-1062647:+ | gene-YDR321W_FaliES1 | rna-NM_001180629.3_FaliES1 | cds-NP_010607.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:14014-15159:+ | gene-YDR321W_JAY291 | rna-NM_001180629.3_JAY291 | cds-NP_010607.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1067536-1068681:+ | gene-YDR321W_MUCL30387 | rna-NM_001180629.3_MUCL30387 | cds-NP_010607.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1056471-1057616:+ | gene-YDR321W_MUCL30388 | rna-NM_001180629.3_MUCL30388 | cds-NP_010607.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1040998-1042143:+ | gene-YDR321W_MUCL39482 | rna-NM_001180629.3_MUCL39482 | cds-NP_010607.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:988085-989230:+ | gene-YDR321W_MUCL42920 | rna-NM_001180629.3_MUCL42920 | cds-NP_010607.3_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1108625-1109770:+ | gene-YDR321W_NCIM3186 | rna-NM_001180629.3_NCIM3186 | cds-NP_010607.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1054289-1055434:+ | gene-YDR321W_NCYC1407 | rna-NM_001180629.3_NCYC1407 | cds-NP_010607.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1065291-1066436:+ | gene-YDR321W_PE2H3 | rna-NM_001180629.3_PE2H3 | cds-NP_010607.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1070876-1072021:+ | gene-YDR321W_PE2H4 | rna-NM_001180629.3_PE2H4 | cds-NP_010607.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1108702-1109847:+ | gene-YDR321W_S288C | rna-NM_001180629.3_S288C | cds-NP_010607.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:79521-80666:+ | gene-YDR321W_SA1 | rna-NM_001180629.3_SA1 | cds-NP_010607.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1065775-1066920:+ | gene-YDR321W_ThermosaccDry | rna-NM_001180629.3_ThermosaccDry | cds-NP_010607.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1081703-1082848:+ | gene-YDR321W_VR1 | rna-NM_001180629.3_VR1 | cds-NP_010607.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:109885-111030:+ | gene-YDR321W_ZTW1 | rna-NM_001180629.3_ZTW1 | cds-NP_010607.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1061247-1062392:+ | gene-YDR321W_Sparadoxus | rna-NM_001180629.3_Sparadoxus | cds-NP_010607.3_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |