Gene name: ASK1
Reference locus (S288C): YKL052C
Gene biotype: protein_coding
Description: Essential subunit of the Dam1 complex (aka DASH complex); couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases; sumoylated in an Mms21p-dependent manner; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): DAD2 (0.999); DAD1 (0.999); SPC19 (0.999); SPC34 (0.999); DAM1 (0.997); DUO1 (0.997); DAD4 (0.996); DAD3 (0.996); HSK3 (0.996); DSN1 (0.954); SPC24 (0.941); CHL4 (0.94); IML3 (0.918); NUF2 (0.862); NDC80 (0.86); IPL1 (0.845); SLI15 (0.801); FIN1 (0.794); CSE4 (0.783); MTW1 (0.779)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:325664-326542:- | gene-YKL052C_AKU4011 | rna-NM_001179618.1_AKU4011 | cds-NP_012872.2_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:317466-318344:+ | gene-YKL052C_BG1 | rna-NM_001179618.1_BG1 | cds-NP_012872.2_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:344695-345573:- | gene-YKL052C_Bruggeman | rna-NM_001179618.1_Bruggeman | cds-NP_012872.2_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:341123-342001:- | gene-YKL052C_CAT1 | rna-NM_001179618.1_CAT1 | cds-NP_012872.2_CAT1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:338394-339272:- | gene-YKL052C_CBS1585 | rna-NM_001179618.1_CBS1585 | cds-NP_012872.2_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:336526-337404:- | gene-YKL052C_CBS436 | rna-NM_001179618.1_CBS436 | cds-NP_012872.2_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:322528-323406:- | gene-YKL052C_CBS6412 | rna-NM_001179618.1_CBS6412 | cds-NP_012872.2_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:338356-339234:- | gene-YKL052C_CBS6413 | rna-NM_001179618.1_CBS6413 | cds-NP_012872.2_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:339328-340206:- | gene-YKL052C_CENPK1137D | rna-NM_001179618.1_CENPK1137D | cds-NP_012872.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:336349-337227:- | gene-YKL052C_EthanolRed | rna-NM_001179618.1_EthanolRed | cds-NP_012872.2_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:337162-338040:- | gene-YKL052C_FaliES1 | rna-NM_001179618.1_FaliES1 | cds-NP_012872.2_FaliES1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000080.1:42087-42965:- | gene-YKL052C_JAY291 | rna-NM_001179618.1_JAY291 | cds-NP_012872.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:345596-346474:- | gene-YKL052C_MUCL30387 | rna-NM_001179618.1_MUCL30387 | cds-NP_012872.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:340485-341363:- | gene-YKL052C_MUCL30388 | rna-NM_001179618.1_MUCL30388 | cds-NP_012872.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:337690-338568:- | gene-YKL052C_MUCL39482 | rna-NM_001179618.1_MUCL39482 | cds-NP_012872.2_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:342545-343423:- | gene-YKL052C_MUCL42920 | rna-NM_001179618.1_MUCL42920 | cds-NP_012872.2_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:339657-340535:- | gene-YKL052C_NCIM3186 | rna-NM_001179618.1_NCIM3186 | cds-NP_012872.2_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:337886-338764:- | gene-YKL052C_NCYC1407 | rna-NM_001179618.1_NCYC1407 | cds-NP_012872.2_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:362429-363307:- | gene-YKL052C_PE2H3 | rna-NM_001179618.1_PE2H3 | cds-NP_012872.2_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:347169-348047:- | gene-YKL052C_PE2H4 | rna-NM_001179618.1_PE2H4 | cds-NP_012872.2_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:339668-340546:- | gene-YKL052C_S288C | rna-NM_001179618.1_S288C | cds-NP_012872.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:17770-18648:- | gene-YKL052C_SA1 | rna-NM_001179618.1_SA1 | cds-NP_012872.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:338352-339230:- | gene-YKL052C_ThermosaccDry | rna-NM_001179618.1_ThermosaccDry | cds-NP_012872.2_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:337498-338376:- | gene-YKL052C_VR1 | rna-NM_001179618.1_VR1 | cds-NP_012872.2_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:336380-337258:- | gene-YKL052C_ZTW1 | rna-NM_001179618.1_ZTW1 | cds-NP_012872.2_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:355584-356447:- | gene-YKL052C_Sparadoxus | rna-NM_001179618.1_Sparadoxus | cds-NP_012872.2_Sparadoxus | 86.6 | 97.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |