Gene name: ASI3
Reference locus (S288C): YNL008C
Gene biotype: protein_coding
Description: Protein ASI3; Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids
Top 10 interactors (score): ASI2 (0.998); ASI1 (0.962); SLX5 (0.907); CDC4 (0.907); SLX8 (0.906); CDC23 (0.9); SWM1 (0.9); APC11 (0.9); DOC1 (0.9); MET30 (0.9); CDC26 (0.9); APC2 (0.9); APC5 (0.9); APC4 (0.9); CDC16 (0.9); MND2 (0.9); APC9 (0.9); CDC27 (0.9); APC1 (0.9); STP1 (0.883)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:599218-601248:- | gene-YNL008C_AKU4011 | rna-NM_001182847.2_AKU4011 | cds-NP_014390.2_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:501664-503694:- | gene-YNL008C_BG1 | rna-NM_001182847.2_BG1 | cds-NP_014390.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:616095-618125:- | gene-YNL008C_Bruggeman | rna-NM_001182847.2_Bruggeman | cds-NP_014390.2_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:651457-653487:- | gene-YNL008C_CAT1 | rna-NM_001182847.2_CAT1 | cds-NP_014390.2_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:604915-606945:- | gene-YNL008C_CBS1585 | rna-NM_001182847.2_CBS1585 | cds-NP_014390.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:666967-668997:- | gene-YNL008C_CBS436 | rna-NM_001182847.2_CBS436 | cds-NP_014390.2_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:594723-596753:- | gene-YNL008C_CBS6412 | rna-NM_001182847.2_CBS6412 | cds-NP_014390.2_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:595886-597916:- | gene-YNL008C_CBS6413 | rna-NM_001182847.2_CBS6413 | cds-NP_014390.2_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:609861-611891:- | gene-YNL008C_CENPK1137D | rna-NM_001182847.2_CENPK1137D | cds-NP_014390.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:601285-603315:- | gene-YNL008C_EthanolRed | rna-NM_001182847.2_EthanolRed | cds-NP_014390.2_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:592054-594084:- | gene-YNL008C_FaliES1 | rna-NM_001182847.2_FaliES1 | cds-NP_014390.2_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000008.1:13879-15909:+ | gene-YNL008C_JAY291 | rna-NM_001182847.2_JAY291 | cds-NP_014390.2_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:614184-616214:- | gene-YNL008C_MUCL30387 | rna-NM_001182847.2_MUCL30387 | cds-NP_014390.2_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:655014-657044:- | gene-YNL008C_MUCL30388 | rna-NM_001182847.2_MUCL30388 | cds-NP_014390.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:596423-598453:- | gene-YNL008C_MUCL39482 | rna-NM_001182847.2_MUCL39482 | cds-NP_014390.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:600278-602308:- | gene-YNL008C_MUCL42920 | rna-NM_001182847.2_MUCL42920 | cds-NP_014390.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:616180-618210:- | gene-YNL008C_NCIM3186 | rna-NM_001182847.2_NCIM3186 | cds-NP_014390.2_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:598676-600706:- | gene-YNL008C_NCYC1407 | rna-NM_001182847.2_NCYC1407 | cds-NP_014390.2_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:600656-602686:- | gene-YNL008C_PE2H3 | rna-NM_001182847.2_PE2H3 | cds-NP_014390.2_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:601974-604004:- | gene-YNL008C_PE2H4 | rna-NM_001182847.2_PE2H4 | cds-NP_014390.2_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:616211-618241:- | gene-YNL008C_S288C | rna-NM_001182847.2_S288C | cds-NP_014390.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:13881-15911:- | gene-YNL008C_SA1 | rna-NM_001182847.2_SA1 | cds-NP_014390.2_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:592394-594424:- | gene-YNL008C_ThermosaccDry | rna-NM_001182847.2_ThermosaccDry | cds-NP_014390.2_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:635001-637031:- | gene-YNL008C_VR1 | rna-NM_001182847.2_VR1 | cds-NP_014390.2_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:501271-503301:- | gene-YNL008C_ZTW1 | rna-NM_001182847.2_ZTW1 | cds-NP_014390.2_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:607442-609472:- | gene-YNL008C_Sparadoxus | rna-NM_001182847.2_Sparadoxus | cds-NP_014390.2_Sparadoxus | 86.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |