ASI2 (YNL159C)


Gene profile

Gene name: ASI2
Reference locus (S288C): YNL159C
Gene biotype: protein_coding

Description: Protein ASI2; Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and inner for ubiquitin-mediated degradation; acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids

Top 10 interactors (score): ASI3 (0.998); ASI1 (0.998); APC9 (0.904); MET30 (0.9); MND2 (0.9); CDC27 (0.9); SLX5 (0.9); APC4 (0.9); SLX8 (0.9); CDC26 (0.9); APC2 (0.9); APC1 (0.9); CDC4 (0.9); CDC16 (0.9); APC11 (0.9); CDC23 (0.9); DOC1 (0.9); SWM1 (0.9); APC5 (0.9); PTR3 (0.827)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:332190-333059:- gene-YNL159C_AKU4011 rna-NM_001182997.1_AKU4011 cds-NP_014240.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:236218-237087:- gene-YNL159C_BG1 rna-NM_001182997.1_BG1 cds-NP_014240.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:342256-343125:- gene-YNL159C_Bruggeman rna-NM_001182997.1_Bruggeman cds-NP_014240.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:385184-386053:- gene-YNL159C_CAT1 rna-NM_001182997.1_CAT1 cds-NP_014240.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:332841-333710:- gene-YNL159C_CBS1585 rna-NM_001182997.1_CBS1585 cds-NP_014240.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:401199-402068:- gene-YNL159C_CBS436 rna-NM_001182997.1_CBS436 cds-NP_014240.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:328247-329116:- gene-YNL159C_CBS6412 rna-NM_001182997.1_CBS6412 cds-NP_014240.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:329275-330144:- gene-YNL159C_CBS6413 rna-NM_001182997.1_CBS6413 cds-NP_014240.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:332292-333161:- gene-YNL159C_CENPK1137D rna-NM_001182997.1_CENPK1137D cds-NP_014240.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:329173-330042:- gene-YNL159C_EthanolRed rna-NM_001182997.1_EthanolRed cds-NP_014240.1_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:325086-325955:- gene-YNL159C_FaliES1 rna-NM_001182997.1_FaliES1 cds-NP_014240.1_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000439.1:17694-18563:+ gene-YNL159C_JAY291 rna-NM_001182997.1_JAY291 cds-NP_014240.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:338077-338946:- gene-YNL159C_MUCL30387 rna-NM_001182997.1_MUCL30387 cds-NP_014240.1_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:372630-373499:- gene-YNL159C_MUCL30388 rna-NM_001182997.1_MUCL30388 cds-NP_014240.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:330081-330950:- gene-YNL159C_MUCL39482 rna-NM_001182997.1_MUCL39482 cds-NP_014240.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:332484-333353:- gene-YNL159C_MUCL42920 rna-NM_001182997.1_MUCL42920 cds-NP_014240.1_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:338447-339316:- gene-YNL159C_NCIM3186 rna-NM_001182997.1_NCIM3186 cds-NP_014240.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:332175-333044:- gene-YNL159C_NCYC1407 rna-NM_001182997.1_NCYC1407 cds-NP_014240.1_NCYC1407 99.5 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:329169-330038:- gene-YNL159C_PE2H3 rna-NM_001182997.1_PE2H3 cds-NP_014240.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:328557-329426:- gene-YNL159C_PE2H4 rna-NM_001182997.1_PE2H4 cds-NP_014240.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:338478-339347:- gene-YNL159C_S288C rna-NM_001182997.1_S288C cds-NP_014240.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:74204-75073:+ gene-YNL159C_SA1 rna-NM_001182997.1_SA1 cds-NP_014240.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:325943-326812:- gene-YNL159C_ThermosaccDry rna-NM_001182997.1_ThermosaccDry cds-NP_014240.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:344498-345367:- gene-YNL159C_VR1 rna-NM_001182997.1_VR1 cds-NP_014240.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:235765-236634:- gene-YNL159C_ZTW1 rna-NM_001182997.1_ZTW1 cds-NP_014240.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:336586-337455:- gene-YNL159C_Sparadoxus rna-NM_001182997.1_Sparadoxus cds-NP_014240.1_Sparadoxus 88.5 99.8 Verified 1 1 1 False True False False False

Additional files