Gene name: ASI1
Reference locus (S288C): YMR119W
Gene biotype: protein_coding
Description: Protein ASI1; Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; the Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids
Top 10 interactors (score): ASI2 (0.998); ASI3 (0.962); CDC16 (0.907); CDC4 (0.906); SLX8 (0.906); SLX5 (0.906); APC5 (0.9); SWM1 (0.9); CDC26 (0.9); APC2 (0.9); APC1 (0.9); APC4 (0.9); MET30 (0.9); MND2 (0.9); APC9 (0.9); CDC27 (0.9); DOC1 (0.9); APC11 (0.9); CDC23 (0.9); UBC7 (0.871)
Homologues (species, bitscore): AT2G35330 (Arabidopsis thaliana, 50.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:544710-546584:+ | gene-YMR119W_AKU4011 | rna-NM_001182619.1_AKU4011 | cds-NP_013837.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000068.1:125955-127829:- | gene-YMR119W_BG1 | rna-NM_001182619.1_BG1 | cds-NP_013837.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:487632-489506:+ | gene-YMR119W_Bruggeman | rna-NM_001182619.1_Bruggeman | cds-NP_013837.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:489303-491177:+ | gene-YMR119W_CAT1 | rna-NM_001182619.1_CAT1 | cds-NP_013837.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:477633-479507:+ | gene-YMR119W_CBS1585 | rna-NM_001182619.1_CBS1585 | cds-NP_013837.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:481496-483370:+ | gene-YMR119W_CBS436 | rna-NM_001182619.1_CBS436 | cds-NP_013837.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:590626-592500:+ | gene-YMR119W_CBS6412 | rna-NM_001182619.1_CBS6412 | cds-NP_013837.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:476193-478067:+ | gene-YMR119W_CBS6413 | rna-NM_001182619.1_CBS6413 | cds-NP_013837.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:499861-501735:+ | gene-YMR119W_CENPK1137D | rna-NM_001182619.1_CENPK1137D | cds-NP_013837.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:475951-477825:+ | gene-YMR119W_EthanolRed | rna-NM_001182619.1_EthanolRed | cds-NP_013837.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:481865-483739:+ | gene-YMR119W_FaliES1 | rna-NM_001182619.1_FaliES1 | cds-NP_013837.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000294.1:43359-45233:- | gene-YMR119W_JAY291 | rna-NM_001182619.1_JAY291 | cds-NP_013837.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:482611-484485:+ | gene-YMR119W_MUCL30387 | rna-NM_001182619.1_MUCL30387 | cds-NP_013837.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:487727-489601:+ | gene-YMR119W_MUCL30388 | rna-NM_001182619.1_MUCL30388 | cds-NP_013837.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:478334-480208:+ | gene-YMR119W_MUCL39482 | rna-NM_001182619.1_MUCL39482 | cds-NP_013837.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:484746-486620:+ | gene-YMR119W_MUCL42920 | rna-NM_001182619.1_MUCL42920 | cds-NP_013837.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:505287-507161:+ | gene-YMR119W_NCIM3186 | rna-NM_001182619.1_NCIM3186 | cds-NP_013837.1_NCIM3186 | 94.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:477972-479846:+ | gene-YMR119W_NCYC1407 | rna-NM_001182619.1_NCYC1407 | cds-NP_013837.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:488402-490276:+ | gene-YMR119W_PE2H3 | rna-NM_001182619.1_PE2H3 | cds-NP_013837.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:488856-490730:+ | gene-YMR119W_PE2H4 | rna-NM_001182619.1_PE2H4 | cds-NP_013837.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:505333-507207:+ | gene-YMR119W_S288C | rna-NM_001182619.1_S288C | cds-NP_013837.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000048.1:64055-65929:- | gene-YMR119W_SA1 | rna-NM_001182619.1_SA1 | cds-NP_013837.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:478349-480223:+ | gene-YMR119W_ThermosaccDry | rna-NM_001182619.1_ThermosaccDry | cds-NP_013837.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:490352-492226:+ | gene-YMR119W_VR1 | rna-NM_001182619.1_VR1 | cds-NP_013837.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:453355-455229:+ | gene-YMR119W_ZTW1 | rna-NM_001182619.1_ZTW1 | cds-NP_013837.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:489609-491495:+ | gene-YMR119W_Sparadoxus | rna-NM_001182619.1_Sparadoxus | cds-NP_013837.1_Sparadoxus | 86.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |