Gene name: ASC1
Reference locus (S288C): YMR116C
Gene biotype: protein_coding
Description: G-protein beta subunit and guanine dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; required to prevent frameshifting at ribosomes stalled at repeated CGA codons; regulates P-body formation induced by replication stress; represses Gcn4p in the absence of amino acid starvation
Top 10 interactors (score): RPS9A (0.999); RPL26A (0.999); RPS9B (0.999); RPS28A (0.999); RPL28 (0.999); RPS15 (0.999); RPS14A (0.999); RPP1A (0.999); RPS11B (0.999); RPL6B (0.999); RPL2B (0.999); FUN12 (0.999); RPS16A (0.999); RPL31A (0.999); RPS19B (0.999); EFT1 (0.999); RPS24A (0.999); RPS24B (0.999); RPL5 (0.999); RPL1B (0.999)
Homologues (species, bitscore): GNB2L1 (Homo sapiens, 347.4); Gnb2l1 (Mus musculus, 347.4); gnb2l1 (Danio rerio, 345.9); gnb2l1 (Xenopus tropicalis, 349.7); Rack1 (Drosophila melanogaster, 327.8); rack-1 (Caenorhabditis elegans, 312.0); RACK1C_AT (Arabidopsis thaliana, 303.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:537628-538860:- | gene-YMR116C_AKU4011 | rna-NM_001182616.1_AKU4011 | cds-NP_013834.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:3988-5220:+ | gene-YMR116C_BG1 | rna-NM_001182616.1_BG1 | cds-NP_013834.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:479814-481046:- | gene-YMR116C_Bruggeman | rna-NM_001182616.1_Bruggeman | cds-NP_013834.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:481031-482263:- | gene-YMR116C_CAT1 | rna-NM_001182616.1_CAT1 | cds-NP_013834.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:471071-472303:- | gene-YMR116C_CBS1585 | rna-NM_001182616.1_CBS1585 | cds-NP_013834.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:475987-477219:- | gene-YMR116C_CBS436 | rna-NM_001182616.1_CBS436 | cds-NP_013834.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:583678-584910:- | gene-YMR116C_CBS6412 | rna-NM_001182616.1_CBS6412 | cds-NP_013834.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:469832-471064:- | gene-YMR116C_CBS6413 | rna-NM_001182616.1_CBS6413 | cds-NP_013834.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:493981-495213:- | gene-YMR116C_CENPK1137D | rna-NM_001182616.1_CENPK1137D | cds-NP_013834.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:470250-471482:- | gene-YMR116C_EthanolRed | rna-NM_001182616.1_EthanolRed | cds-NP_013834.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:475571-476802:- | gene-YMR116C_FaliES1 | rna-NM_001182616.1_FaliES1 | cds-NP_013834.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000380.1:3869-5101:+ | gene-YMR116C_JAY291 | rna-NM_001182616.1_JAY291 | cds-NP_013834.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:476734-477966:- | gene-YMR116C_MUCL30387 | rna-NM_001182616.1_MUCL30387 | cds-NP_013834.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:480985-482217:- | gene-YMR116C_MUCL30388 | rna-NM_001182616.1_MUCL30388 | cds-NP_013834.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:470872-472104:- | gene-YMR116C_MUCL39482 | rna-NM_001182616.1_MUCL39482 | cds-NP_013834.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:477884-479115:- | gene-YMR116C_MUCL42920 | rna-NM_001182616.1_MUCL42920 | cds-NP_013834.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:499410-500642:- | gene-YMR116C_NCIM3186 | rna-NM_001182616.1_NCIM3186 | cds-NP_013834.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:470768-472000:- | gene-YMR116C_NCYC1407 | rna-NM_001182616.1_NCYC1407 | cds-NP_013834.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:476584-477816:- | gene-YMR116C_PE2H3 | rna-NM_001182616.1_PE2H3 | cds-NP_013834.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:482679-483911:- | gene-YMR116C_PE2H4 | rna-NM_001182616.1_PE2H4 | cds-NP_013834.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:499456-500688:- | gene-YMR116C_S288C | rna-NM_001182616.1_S288C | cds-NP_013834.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000048.1:70920-72152:+ | gene-YMR116C_SA1 | rna-NM_001182616.1_SA1 | cds-NP_013834.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:471430-472661:- | gene-YMR116C_ThermosaccDry | rna-NM_001182616.1_ThermosaccDry | cds-NP_013834.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:483170-484401:- | gene-YMR116C_VR1 | rna-NM_001182616.1_VR1 | cds-NP_013834.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:447478-448710:- | gene-YMR116C_ZTW1 | rna-NM_001182616.1_ZTW1 | cds-NP_013834.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:484480-485722:- | gene-YMR116C_Sparadoxus | rna-NM_001182616.1_Sparadoxus | cds-NP_013834.1_Sparadoxus | 97.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |