Gene name: ARO4
Reference locus (S288C): YBR249C
Gene biotype: protein_coding
Description: Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited; 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase; catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan; relative distribution to the nucleus increases upon DNA replication stress
Top 10 interactors (score): ARO1 (0.993); ARO2 (0.965); ARO3 (0.959); ARO7 (0.958); TRP3 (0.92); TYR1 (0.875); ARO8 (0.863); HIS7 (0.822); TKL1 (0.813); ILV6 (0.808); DED81 (0.806); TRP4 (0.795); PHA2 (0.785); ILV3 (0.783); TRP5 (0.771); GCN4 (0.769); ARO10 (0.766); HIS1 (0.74); TRP2 (0.732); ARO9 (0.728)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:701182-702294:- | gene-YBR249C_AKU4011 | rna-NM_001178597.1_AKU4011 | cds-NP_009808.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:72187-73299:- | gene-YBR249C_BG1 | rna-NM_001178597.1_BG1 | cds-NP_009808.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:702334-703446:- | gene-YBR249C_Bruggeman | rna-NM_001178597.1_Bruggeman | cds-NP_009808.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:705825-706937:- | gene-YBR249C_CAT1 | rna-NM_001178597.1_CAT1 | cds-NP_009808.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:692748-693860:- | gene-YBR249C_CBS1585 | rna-NM_001178597.1_CBS1585 | cds-NP_009808.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:699178-700290:- | gene-YBR249C_CBS436 | rna-NM_001178597.1_CBS436 | cds-NP_009808.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:787353-788465:- | gene-YBR249C_CBS6412 | rna-NM_001178597.1_CBS6412 | cds-NP_009808.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:698796-699908:- | gene-YBR249C_CBS6413 | rna-NM_001178597.1_CBS6413 | cds-NP_009808.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:710792-711904:- | gene-YBR249C_CENPK1137D | rna-NM_001178597.1_CENPK1137D | cds-NP_009808.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:824204-825316:- | gene-YBR249C_EthanolRed | rna-NM_001178597.1_EthanolRed | cds-NP_009808.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:717551-718663:- | gene-YBR249C_FaliES1 | rna-NM_001178597.1_FaliES1 | cds-NP_009808.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:85402-86514:+ | gene-YBR249C_JAY291 | rna-NM_001178597.1_JAY291 | cds-NP_009808.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:704377-705489:- | gene-YBR249C_MUCL30387 | rna-NM_001178597.1_MUCL30387 | cds-NP_009808.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:721460-722572:- | gene-YBR249C_MUCL30388 | rna-NM_001178597.1_MUCL30388 | cds-NP_009808.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:691055-692167:- | gene-YBR249C_MUCL39482 | rna-NM_001178597.1_MUCL39482 | cds-NP_009808.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:700912-702024:- | gene-YBR249C_MUCL42920 | rna-NM_001178597.1_MUCL42920 | cds-NP_009808.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:716679-717791:- | gene-YBR249C_NCIM3186 | rna-NM_001178597.1_NCIM3186 | cds-NP_009808.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:692944-694056:- | gene-YBR249C_NCYC1407 | rna-NM_001178597.1_NCYC1407 | cds-NP_009808.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:716049-717161:- | gene-YBR249C_PE2H3 | rna-NM_001178597.1_PE2H3 | cds-NP_009808.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:713725-714837:- | gene-YBR249C_PE2H4 | rna-NM_001178597.1_PE2H4 | cds-NP_009808.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:716882-717994:- | gene-YBR249C_S288C | rna-NM_001178597.1_S288C | cds-NP_009808.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:72010-73122:- | gene-YBR249C_SA1 | rna-NM_001178597.1_SA1 | cds-NP_009808.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:716543-717655:- | gene-YBR249C_ThermosaccDry | rna-NM_001178597.1_ThermosaccDry | cds-NP_009808.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:696757-697869:- | gene-YBR249C_VR1 | rna-NM_001178597.1_VR1 | cds-NP_009808.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:689394-690506:- | gene-YBR249C_ZTW1 | rna-NM_001178597.1_ZTW1 | cds-NP_009808.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:733355-734467:- | gene-YBR249C_Sparadoxus | rna-NM_001178597.1_Sparadoxus | cds-NP_009808.1_Sparadoxus | 94.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |