ARK1 (YNL020C)


Gene profile

Gene name: ARK1
Reference locus (S288C): YNL020C
Gene biotype: protein_coding

Description: Actin-regulating kinase 1; Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication

Top 10 interactors (score): ABP1 (0.995); PAN1 (0.97); SLA1 (0.947); SLA2 (0.937); END3 (0.9); YAP1801 (0.862); EDE1 (0.856); APL3 (0.846); APM4 (0.84); ENT1 (0.835); SRV2 (0.809); SCD5 (0.774); SAC6 (0.774); ENT2 (0.772); ACT1 (0.75); PRK1 (0.747); LAS17 (0.743); ARP2 (0.742); COF1 (0.729); YSC84 (0.719)

Homologues (species, bitscore): BMP2K (Homo sapiens, 221.1); Bmp2k (Mus musculus, 212.6); aak1 (Danio rerio, 215.3); aak1 (Xenopus tropicalis, 218.8); Nak (Drosophila melanogaster, 191.4); sel-5 (Caenorhabditis elegans, 172.2); AT2G32850 (Arabidopsis thaliana, 180.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:578082-579998:- gene-YNL020C_AKU4011 rna-NM_001182859.1_AKU4011 cds-NP_014378.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:460146-462062:+ gene-YNL020C_BG1 rna-NM_001182859.1_BG1 cds-NP_014378.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:595502-597418:- gene-YNL020C_Bruggeman rna-NM_001182859.1_Bruggeman cds-NP_014378.1_Bruggeman 99.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:630951-632867:- gene-YNL020C_CAT1 rna-NM_001182859.1_CAT1 cds-NP_014378.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:583766-585682:- gene-YNL020C_CBS1585 rna-NM_001182859.1_CBS1585 cds-NP_014378.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:646176-648092:- gene-YNL020C_CBS436 rna-NM_001182859.1_CBS436 cds-NP_014378.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:573599-575515:- gene-YNL020C_CBS6412 rna-NM_001182859.1_CBS6412 cds-NP_014378.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:574940-576856:- gene-YNL020C_CBS6413 rna-NM_001182859.1_CBS6413 cds-NP_014378.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:589230-591146:- gene-YNL020C_CENPK1137D rna-NM_001182859.1_CENPK1137D cds-NP_014378.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:580168-582084:- gene-YNL020C_EthanolRed rna-NM_001182859.1_EthanolRed cds-NP_014378.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:571192-573108:- gene-YNL020C_FaliES1 rna-NM_001182859.1_FaliES1 cds-NP_014378.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000387.1:727-2643:+ gene-YNL020C_JAY291 rna-NM_001182859.1_JAY291 cds-NP_014378.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:591384-593300:- gene-YNL020C_MUCL30387 rna-NM_001182859.1_MUCL30387 cds-NP_014378.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:634178-636094:- gene-YNL020C_MUCL30388 rna-NM_001182859.1_MUCL30388 cds-NP_014378.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:575361-577277:- gene-YNL020C_MUCL39482 rna-NM_001182859.1_MUCL39482 cds-NP_014378.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:578919-580835:- gene-YNL020C_MUCL42920 rna-NM_001182859.1_MUCL42920 cds-NP_014378.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:595592-597508:- gene-YNL020C_NCIM3186 rna-NM_001182859.1_NCIM3186 cds-NP_014378.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:577566-579482:- gene-YNL020C_NCYC1407 rna-NM_001182859.1_NCYC1407 cds-NP_014378.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:580089-582005:- gene-YNL020C_PE2H3 rna-NM_001182859.1_PE2H3 cds-NP_014378.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:581407-583323:- gene-YNL020C_PE2H4 rna-NM_001182859.1_PE2H4 cds-NP_014378.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:595623-597539:- gene-YNL020C_S288C rna-NM_001182859.1_S288C cds-NP_014378.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000109.1:21648-23564:- gene-YNL020C_SA1 rna-NM_001182859.1_SA1 cds-NP_014378.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:571779-573695:- gene-YNL020C_ThermosaccDry rna-NM_001182859.1_ThermosaccDry cds-NP_014378.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:569056-570972:+ gene-YNL020C_VR1 rna-NM_001182859.1_VR1 cds-NP_014378.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:459745-461661:+ gene-YNL020C_ZTW1 rna-NM_001182859.1_ZTW1 cds-NP_014378.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:586900-588834:- gene-YNL020C_Sparadoxus rna-NM_001182859.1_Sparadoxus cds-NP_014378.1_Sparadoxus 86.6 99.8 Verified 1 1 1 False True False False False

Additional files