Gene name: ARE2
Reference locus (S288C): YNR019W
Gene biotype: protein_coding
Description: Sterol O-acyltransferase 2; Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen; ARE2 has a paralog, ARE1, that arose from the whole genome duplication; Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily
Top 10 interactors (score): LRO1 (0.998); DGA1 (0.998); TGL1 (0.982); YEH2 (0.981); YEH1 (0.98); ARE1 (0.96); PAH1 (0.931); TGL3 (0.916); ALE1 (0.913); ARV1 (0.909); TGL4 (0.843); OLE1 (0.833); TGL5 (0.815); FAT1 (0.793); AYR1 (0.788); DGK1 (0.78); SEI1 (0.75); LPP1 (0.735); POX1 (0.732); YJU3 (0.73)
Homologues (species, bitscore): DGAT1 (Homo sapiens, 124.4); Dgat1 (Mus musculus, 122.9); dgat1a (Danio rerio, 127.9); soat1 (Xenopus tropicalis, 111.7); Mdy (Drosophila melanogaster, 123.2); mboa-2 (Caenorhabditis elegans, 131.7); TAG1 (Arabidopsis thaliana, 134.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:648955-650883:+ | gene-YNR019W_AKU4011 | rna-NM_001183196.1_AKU4011 | cds-NP_014416.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:556869-558797:+ | gene-YNR019W_BG1 | rna-NM_001183196.1_BG1 | cds-NP_014416.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:666460-668388:+ | gene-YNR019W_Bruggeman | rna-NM_001183196.1_Bruggeman | cds-NP_014416.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:700642-702570:+ | gene-YNR019W_CAT1 | rna-NM_001183196.1_CAT1 | cds-NP_014416.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:654748-656676:+ | gene-YNR019W_CBS1585 | rna-NM_001183196.1_CBS1585 | cds-NP_014416.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:716411-718339:+ | gene-YNR019W_CBS436 | rna-NM_001183196.1_CBS436 | cds-NP_014416.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:643942-645870:+ | gene-YNR019W_CBS6412 | rna-NM_001183196.1_CBS6412 | cds-NP_014416.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:645642-647570:+ | gene-YNR019W_CBS6413 | rna-NM_001183196.1_CBS6413 | cds-NP_014416.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:659025-660989:+ | gene-YNR019W_CENPK1137D | rna-NM_001183196.1_CENPK1137D | cds-NP_014416.1_CENPK1137D | 92.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:650692-652620:+ | gene-YNR019W_EthanolRed | rna-NM_001183196.1_EthanolRed | cds-NP_014416.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:641891-643819:+ | gene-YNR019W_FaliES1 | rna-NM_001183196.1_FaliES1 | cds-NP_014416.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000037.1:58967-60895:- | gene-YNR019W_JAY291 | rna-NM_001183196.1_JAY291 | cds-NP_014416.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:664206-666134:+ | gene-YNR019W_MUCL30387 | rna-NM_001183196.1_MUCL30387 | cds-NP_014416.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:705014-706942:+ | gene-YNR019W_MUCL30388 | rna-NM_001183196.1_MUCL30388 | cds-NP_014416.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:646251-648179:+ | gene-YNR019W_MUCL39482 | rna-NM_001183196.1_MUCL39482 | cds-NP_014416.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:650417-652345:+ | gene-YNR019W_MUCL42920 | rna-NM_001183196.1_MUCL42920 | cds-NP_014416.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:665308-667236:+ | gene-YNR019W_NCIM3186 | rna-NM_001183196.1_NCIM3186 | cds-NP_014416.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:648757-650685:+ | gene-YNR019W_NCYC1407 | rna-NM_001183196.1_NCYC1407 | cds-NP_014416.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:649822-651750:+ | gene-YNR019W_PE2H3 | rna-NM_001183196.1_PE2H3 | cds-NP_014416.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:651140-653068:+ | gene-YNR019W_PE2H4 | rna-NM_001183196.1_PE2H4 | cds-NP_014416.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:665339-667267:+ | gene-YNR019W_S288C | rna-NM_001183196.1_S288C | cds-NP_014416.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:63047-64975:+ | gene-YNR019W_SA1 | rna-NM_001183196.1_SA1 | cds-NP_014416.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:642234-644162:+ | gene-YNR019W_ThermosaccDry | rna-NM_001183196.1_ThermosaccDry | cds-NP_014416.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:684164-686092:+ | gene-YNR019W_VR1 | rna-NM_001183196.1_VR1 | cds-NP_014416.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:551640-553568:+ | gene-YNR019W_ZTW1 | rna-NM_001183196.1_ZTW1 | cds-NP_014416.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:656295-658226:+ | gene-YNR019W_Sparadoxus | rna-NM_001183196.1_Sparadoxus | cds-NP_014416.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |