Gene name: ARE1
Reference locus (S288C): YCR048W
Gene biotype: protein_coding
Description: Sterol O-acyltransferase 1; Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen; ARE1 has a paralog, ARE2, that arose from the whole genome duplication; Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily
Top 10 interactors (score): DGA1 (0.99); LRO1 (0.987); ARE2 (0.96); TGL1 (0.944); YEH2 (0.931); YEH1 (0.927); YCR051W (0.843); BUD23 (0.802); IMG1 (0.786); ALE1 (0.784); PAH1 (0.753); YCR099C (0.749); SPO11 (0.746); ARV1 (0.731); EMC6 (0.722); YCR047W-A (0.714); YCR022C (0.71); YIR020C (0.71); RRT12 (0.696); EMC10 (0.692)
Homologues (species, bitscore): DGAT1 (Homo sapiens, 98.6); Dgat1 (Mus musculus, 98.2); dgat1b (Danio rerio, 101.7); dgat1 (Xenopus tropicalis, 99.4); Mdy (Drosophila melanogaster, 126.3); mboa-2 (Caenorhabditis elegans, 122.5); TAG1 (Arabidopsis thaliana, 97.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:206405-208219:+ | gene-YCR048W_AKU4011 | rna-NM_001178762.1_AKU4011 | cds-NP_009978.1_AKU4011 | 98.2 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:60590-62422:+ | gene-YCR048W_BG1 | rna-NM_001178762.1_BG1 | cds-NP_009978.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:202364-204178:+ | gene-YCR048W_Bruggeman | rna-NM_001178762.1_Bruggeman | cds-NP_009978.1_Bruggeman | 98.3 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:213721-215553:+ | gene-YCR048W_CAT1 | rna-NM_001178762.1_CAT1 | cds-NP_009978.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:201183-202997:+ | gene-YCR048W_CBS1585 | rna-NM_001178762.1_CBS1585 | cds-NP_009978.1_CBS1585 | 98.1 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:213062-214894:+ | gene-YCR048W_CBS436 | rna-NM_001178762.1_CBS436 | cds-NP_009978.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:192923-194737:+ | gene-YCR048W_CBS6412 | rna-NM_001178762.1_CBS6412 | cds-NP_009978.1_CBS6412 | 98.3 | 99.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:207300-209114:+ | gene-YCR048W_CBS6413 | rna-NM_001178762.1_CBS6413 | cds-NP_009978.1_CBS6413 | 98.1 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:211129-212943:+ | gene-YCR048W_CENPK1137D | rna-NM_001178762.1_CENPK1137D | cds-NP_009978.1_CENPK1137D | 98.2 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:202368-204182:+ | gene-YCR048W_EthanolRed | rna-NM_001178762.1_EthanolRed | cds-NP_009978.1_EthanolRed | 98.3 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:207533-209347:+ | gene-YCR048W_FaliES1 | rna-NM_001178762.1_FaliES1 | cds-NP_009978.1_FaliES1 | 98.2 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000014.1:13832-15646:- | gene-YCR048W_JAY291 | rna-NM_001178762.1_JAY291 | cds-NP_009978.1_JAY291 | 99.0 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:199348-201162:+ | gene-YCR048W_MUCL30387 | rna-NM_001178762.1_MUCL30387 | cds-NP_009978.1_MUCL30387 | 98.6 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:198722-200536:+ | gene-YCR048W_MUCL30388 | rna-NM_001178762.1_MUCL30388 | cds-NP_009978.1_MUCL30388 | 98.3 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:207756-209570:+ | gene-YCR048W_MUCL39482 | rna-NM_001178762.1_MUCL39482 | cds-NP_009978.1_MUCL39482 | 98.2 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:204197-206011:+ | gene-YCR048W_MUCL42920 | rna-NM_001178762.1_MUCL42920 | cds-NP_009978.1_MUCL42920 | 98.3 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:211561-213393:+ | gene-YCR048W_NCIM3186 | rna-NM_001178762.1_NCIM3186 | cds-NP_009978.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:208615-210429:+ | gene-YCR048W_NCYC1407 | rna-NM_001178762.1_NCYC1407 | cds-NP_009978.1_NCYC1407 | 98.1 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:217294-219108:+ | gene-YCR048W_PE2H3 | rna-NM_001178762.1_PE2H3 | cds-NP_009978.1_PE2H3 | 99.0 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:211820-213634:+ | gene-YCR048W_PE2H4 | rna-NM_001178762.1_PE2H4 | cds-NP_009978.1_PE2H4 | 99.0 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:211929-213761:+ | gene-YCR048W_S288C | rna-NM_001178762.1_S288C | cds-NP_009978.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:11812-13644:+ | gene-YCR048W_SA1 | rna-NM_001178762.1_SA1 | cds-NP_009978.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:207516-209330:+ | gene-YCR048W_ThermosaccDry | rna-NM_001178762.1_ThermosaccDry | cds-NP_009978.1_ThermosaccDry | 98.2 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:218774-220606:+ | gene-YCR048W_VR1 | rna-NM_001178762.1_VR1 | cds-NP_009978.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:205339-207153:+ | gene-YCR048W_ZTW1 | rna-NM_001178762.1_ZTW1 | cds-NP_009978.1_ZTW1 | 98.3 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:239474-241306:+ | gene-YCR048W_Sparadoxus | rna-NM_001178762.1_Sparadoxus | cds-NP_009978.1_Sparadoxus | 88.7 | 99.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |