Gene name: ARD1
Reference locus (S288C): YHR013C
Gene biotype: protein_coding
Description: Subunit of protein N-terminal acetyltransferase NatA; NatA comprises Nat1p, Ard1p, Nat5p; acetylates many proteins to influence telomeric silencing, cell cycle, heat-shock resistance, mating, sporulation, early stages of mitophagy; protein abundance increases under DNA replication stress; mutations in human homolog X-linked NAA10 lead to Ogden syndrome (S37P) and intellectual disability (R116W); expression of human NAA10 and NAA15 can complement ard1 nat1 double mutant
Top 10 interactors (score): NAT1 (0.999); NAT5 (0.999); MAK3 (0.998); MAK10 (0.994); MDM20 (0.991); MAP2 (0.982); MAK31 (0.969); MAP1 (0.964); NAT4 (0.952); RPL25 (0.947); NAT3 (0.943); RPL42A (0.904); RPL42B (0.904); RPL35B (0.885); RPL3 (0.884); RPL31A (0.86); RPL39 (0.858); RPL35A (0.854); SIR1 (0.84); RPL30 (0.837)
Homologues (species, bitscore): NAA10 (Homo sapiens, 168.7); Gm16286 (Mus musculus, 171.8); naa10 (Danio rerio, 169.9); naa10 (Xenopus tropicalis, 169.5); vnc (Drosophila melanogaster, 157.5); K07H8.3 (Caenorhabditis elegans, 167.5); AT5G13780 (Arabidopsis thaliana, 161.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:119020-119736:- | gene-YHR013C_AKU4011 | rna-NM_001179143.1_AKU4011 | cds-NP_011877.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:38818-39534:- | gene-YHR013C_BG1 | rna-NM_001179143.1_BG1 | cds-NP_011877.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:125851-126567:- | gene-YHR013C_Bruggeman | rna-NM_001179143.1_Bruggeman | cds-NP_011877.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:120087-120803:- | gene-YHR013C_CAT1 | rna-NM_001179143.1_CAT1 | cds-NP_011877.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:119605-120321:- | gene-YHR013C_CBS1585 | rna-NM_001179143.1_CBS1585 | cds-NP_011877.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:112422-113138:- | gene-YHR013C_CBS436 | rna-NM_001179143.1_CBS436 | cds-NP_011877.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:119202-119918:- | gene-YHR013C_CBS6412 | rna-NM_001179143.1_CBS6412 | cds-NP_011877.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:118938-119654:- | gene-YHR013C_CBS6413 | rna-NM_001179143.1_CBS6413 | cds-NP_011877.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:123889-124605:- | gene-YHR013C_CENPK1137D | rna-NM_001179143.1_CENPK1137D | cds-NP_011877.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:118817-119533:- | gene-YHR013C_EthanolRed | rna-NM_001179143.1_EthanolRed | cds-NP_011877.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:119795-120511:- | gene-YHR013C_FaliES1 | rna-NM_001179143.1_FaliES1 | cds-NP_011877.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000064.1:1710-2426:+ | gene-YHR013C_JAY291 | rna-NM_001179143.1_JAY291 | cds-NP_011877.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:124402-125118:- | gene-YHR013C_MUCL30387 | rna-NM_001179143.1_MUCL30387 | cds-NP_011877.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:125279-125995:- | gene-YHR013C_MUCL30388 | rna-NM_001179143.1_MUCL30388 | cds-NP_011877.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:118632-119348:- | gene-YHR013C_MUCL39482 | rna-NM_001179143.1_MUCL39482 | cds-NP_011877.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:123442-124158:- | gene-YHR013C_MUCL42920 | rna-NM_001179143.1_MUCL42920 | cds-NP_011877.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:130612-131328:- | gene-YHR013C_NCIM3186 | rna-NM_001179143.1_NCIM3186 | cds-NP_011877.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:118046-118762:- | gene-YHR013C_NCYC1407 | rna-NM_001179143.1_NCYC1407 | cds-NP_011877.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:120247-120963:- | gene-YHR013C_PE2H3 | rna-NM_001179143.1_PE2H3 | cds-NP_011877.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:127688-128404:- | gene-YHR013C_PE2H4 | rna-NM_001179143.1_PE2H4 | cds-NP_011877.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:130730-131446:- | gene-YHR013C_S288C | rna-NM_001179143.1_S288C | cds-NP_011877.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000075.1:15427-16143:+ | gene-YHR013C_SA1 | rna-NM_001179143.1_SA1 | cds-NP_011877.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:120884-121600:- | gene-YHR013C_ThermosaccDry | rna-NM_001179143.1_ThermosaccDry | cds-NP_011877.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:126410-127126:- | gene-YHR013C_VR1 | rna-NM_001179143.1_VR1 | cds-NP_011877.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:112122-112838:- | gene-YHR013C_ZTW1 | rna-NM_001179143.1_ZTW1 | cds-NP_011877.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:118516-119232:- | gene-YHR013C_Sparadoxus | rna-NM_001179143.1_Sparadoxus | cds-NP_011877.1_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |