AQR1 (YNL065W)


Gene profile

Gene name: AQR1
Reference locus (S288C): YNL065W
Gene biotype: protein_coding

Description: Probable transporter AQR1; Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids; AQR1 has a paralog, QDR1, that arose from the whole genome duplication; relocalizes from plasma membrane to cytoplasm upon DNA replication stress

Top 10 interactors (score): TPO1 (0.907); HOL1 (0.906); YOR338W (0.853); HAA1 (0.765); PDR12 (0.763); AZR1 (0.751); ATR1 (0.672); VID24 (0.647); VBA4 (0.615); HRK1 (0.614); YGR035C (0.585); TY2A-F (0.567); YFL002W-B (0.567); YMR279C (0.567); YOR343W-A (0.565); PRM7 (0.54); PMA2 (0.534); WAR1 (0.527); PDR18 (0.525); SEC4 (0.516)

Homologues (species, bitscore): sv2ba (Danio rerio, 53.1); hmit-1.2 (Caenorhabditis elegans, 58.9); TMT2 (Arabidopsis thaliana, 54.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:497392-499152:+ gene-YNL065W_AKU4011 rna-NM_001182903.3_AKU4011 cds-NP_014334.3_AKU4011 99.9 100.0 Unannotated 1 1 0 False False False False True
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:401407-403167:+ gene-YNL065W_BG1 rna-NM_001182903.3_BG1 cds-NP_014334.3_BG1 99.6 100.0 Unannotated 1 1 0 False False False False True
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:508119-509879:+ gene-YNL065W_Bruggeman rna-NM_001182903.3_Bruggeman cds-NP_014334.3_Bruggeman 99.7 100.0 Unannotated 1 1 0 False False False False True
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:551111-552871:+ gene-YNL065W_CAT1 rna-NM_001182903.3_CAT1 cds-NP_014334.3_CAT1 99.5 100.0 Unannotated 1 1 0 False False False False True
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:498062-499822:+ gene-YNL065W_CBS1585 rna-NM_001182903.3_CBS1585 cds-NP_014334.3_CBS1585 99.9 100.0 Unannotated 1 1 0 False False False False True
CBS436 GCA_001738355.1 Sake Asia CM005356.1:566479-568128:+ gene-YNL065W_CBS436 rna-NM_001182903.3_CBS436 cds-NP_014334.3_CBS436 93.2 93.6 Unannotated 1 1 0 False False False False True
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:493155-494915:+ gene-YNL065W_CBS6412 rna-NM_001182903.3_CBS6412 cds-NP_014334.3_CBS6412 99.9 100.0 Unannotated 1 1 0 False False False False True
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:494471-496231:+ gene-YNL065W_CBS6413 rna-NM_001182903.3_CBS6413 cds-NP_014334.3_CBS6413 99.9 100.0 Unannotated 1 1 0 False False False False True
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:497688-499448:+ gene-YNL065W_CENPK1137D rna-NM_001182903.3_CENPK1137D cds-NP_014334.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:500213-501973:+ gene-YNL065W_EthanolRed rna-NM_001182903.3_EthanolRed cds-NP_014334.3_EthanolRed 99.9 100.0 Unannotated 1 1 0 False False False False True
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:490738-492498:+ gene-YNL065W_FaliES1 rna-NM_001182903.3_FaliES1 cds-NP_014334.3_FaliES1 99.9 100.0 Unannotated 1 1 0 False False False False True
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000040.1:5842-7602:+ gene-YNL065W_JAY291 rna-NM_001182903.3_JAY291 cds-NP_014334.3_JAY291 99.6 100.0 Unannotated 1 1 0 False False False False True
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:504281-506041:+ gene-YNL065W_MUCL30387 rna-NM_001182903.3_MUCL30387 cds-NP_014334.3_MUCL30387 99.7 100.0 Unannotated 1 1 0 False False False False True
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:539683-541692:+ gene-YNL065W_MUCL30388 rna-NM_001182903.3_MUCL30388 cds-NP_014334.3_MUCL30388 87.2 100.0 Unannotated 1 1 0 False False False False True
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:495464-497224:+ gene-YNL065W_MUCL39482 rna-NM_001182903.3_MUCL39482 cds-NP_014334.3_MUCL39482 99.9 100.0 Unannotated 1 1 0 False False False False True
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:499383-501143:+ gene-YNL065W_MUCL42920 rna-NM_001182903.3_MUCL42920 cds-NP_014334.3_MUCL42920 99.5 100.0 Unannotated 1 1 0 False False False False True
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:503693-505453:+ gene-YNL065W_NCIM3186 rna-NM_001182903.3_NCIM3186 cds-NP_014334.3_NCIM3186 99.8 100.0 Unannotated 1 1 0 False False False False True
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:497515-499275:+ gene-YNL065W_NCYC1407 rna-NM_001182903.3_NCYC1407 cds-NP_014334.3_NCYC1407 99.9 100.0 Unannotated 1 1 0 False False False False True
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:500756-502516:+ gene-YNL065W_PE2H3 rna-NM_001182903.3_PE2H3 cds-NP_014334.3_PE2H3 99.6 100.0 Unannotated 1 1 0 False False False False True
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:495831-497591:+ gene-YNL065W_PE2H4 rna-NM_001182903.3_PE2H4 cds-NP_014334.3_PE2H4 99.6 100.0 Unannotated 1 1 0 False False False False True
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:503724-505484:+ gene-YNL065W_S288C rna-NM_001182903.3_S288C cds-NP_014334.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:88674-90434:+ gene-YNL065W_SA1 rna-NM_001182903.3_SA1 cds-NP_014334.3_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:491613-493373:+ gene-YNL065W_ThermosaccDry rna-NM_001182903.3_ThermosaccDry cds-NP_014334.3_ThermosaccDry 99.9 100.0 Unannotated 1 1 0 False False False False True
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:510718-512477:+ gene-YNL065W_VR1 rna-NM_001182903.3_VR1 cds-NP_014334.3_VR1 99.4 99.9 Unannotated 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:400960-402720:+ gene-YNL065W_ZTW1 rna-NM_001182903.3_ZTW1 cds-NP_014334.3_ZTW1 99.8 100.0 Unannotated 1 1 0 False False False False True
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:507210-508962:+ gene-YNL065W_Sparadoxus rna-NM_001182903.3_Sparadoxus cds-NP_014334.3_Sparadoxus 90.5 99.4 Unannotated 1 1 0 False False False True False

Additional files