APT1 (YML022W)


Gene profile

Gene name: APT1
Reference locus (S288C): YML022W
Gene biotype: protein_coding

Description: Adenine phosphoribosyltransferase; catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis; APT1 has a paralog, APT2, that arose from the whole genome duplication

Top 10 interactors (score): ADO1 (0.993); AAH1 (0.988); ADE13 (0.987); GUA1 (0.982); APT2 (0.982); ADK1 (0.967); ADE16 (0.966); ADE17 (0.966); GUD1 (0.962); GUK1 (0.956); AMD1 (0.955); PNP1 (0.952); ADK2 (0.949); ADE12 (0.942); HAM1 (0.927); TRP5 (0.923); HPT1 (0.915); FAP7 (0.91); PDE1 (0.9); PDE2 (0.9)

Homologues (species, bitscore): APRT (Homo sapiens, 152.1); Aprt (Mus musculus, 153.3); aprt (Danio rerio, 154.1); aprt (Xenopus tropicalis, 147.9); Aprt (Drosophila melanogaster, 145.6); T19B4.3 (Caenorhabditis elegans, 137.5); APT3 (Arabidopsis thaliana, 138.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:278530-279093:+ gene-YML022W_AKU4011 rna-NM_001182380.1_AKU4011 cds-NP_013690.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:263781-264344:- gene-YML022W_BG1 rna-NM_001182380.1_BG1 cds-NP_013690.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:218483-219046:+ gene-YML022W_Bruggeman rna-NM_001182380.1_Bruggeman cds-NP_013690.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:220994-221557:+ gene-YML022W_CAT1 rna-NM_001182380.1_CAT1 cds-NP_013690.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:211480-212043:+ gene-YML022W_CBS1585 rna-NM_001182380.1_CBS1585 cds-NP_013690.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:217014-217577:+ gene-YML022W_CBS436 rna-NM_001182380.1_CBS436 cds-NP_013690.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:325217-325780:+ gene-YML022W_CBS6412 rna-NM_001182380.1_CBS6412 cds-NP_013690.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:210737-211300:+ gene-YML022W_CBS6413 rna-NM_001182380.1_CBS6413 cds-NP_013690.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:223459-224022:+ gene-YML022W_CENPK1137D rna-NM_001182380.1_CENPK1137D cds-NP_013690.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:211504-212067:+ gene-YML022W_EthanolRed rna-NM_001182380.1_EthanolRed cds-NP_013690.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:214468-215031:+ gene-YML022W_FaliES1 rna-NM_001182380.1_FaliES1 cds-NP_013690.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:221885-222448:- gene-YML022W_JAY291 rna-NM_001182380.1_JAY291 cds-NP_013690.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:216214-216777:+ gene-YML022W_MUCL30387 rna-NM_001182380.1_MUCL30387 cds-NP_013690.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:220883-221446:+ gene-YML022W_MUCL30388 rna-NM_001182380.1_MUCL30388 cds-NP_013690.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:211765-212328:+ gene-YML022W_MUCL39482 rna-NM_001182380.1_MUCL39482 cds-NP_013690.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:217319-217882:+ gene-YML022W_MUCL42920 rna-NM_001182380.1_MUCL42920 cds-NP_013690.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:228891-229454:+ gene-YML022W_NCIM3186 rna-NM_001182380.1_NCIM3186 cds-NP_013690.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:211706-212269:+ gene-YML022W_NCYC1407 rna-NM_001182380.1_NCYC1407 cds-NP_013690.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:217605-218168:+ gene-YML022W_PE2H3 rna-NM_001182380.1_PE2H3 cds-NP_013690.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:223700-224263:+ gene-YML022W_PE2H4 rna-NM_001182380.1_PE2H4 cds-NP_013690.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:228937-229500:+ gene-YML022W_S288C rna-NM_001182380.1_S288C cds-NP_013690.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000088.1:9353-9916:- gene-YML022W_SA1 rna-NM_001182380.1_SA1 cds-NP_013690.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:211541-212104:+ gene-YML022W_ThermosaccDry rna-NM_001182380.1_ThermosaccDry cds-NP_013690.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:215546-216109:+ gene-YML022W_VR1 rna-NM_001182380.1_VR1 cds-NP_013690.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:190595-191158:+ gene-YML022W_ZTW1 rna-NM_001182380.1_ZTW1 cds-NP_013690.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:222310-222873:+ gene-YML022W_Sparadoxus rna-NM_001182380.1_Sparadoxus cds-NP_013690.1_Sparadoxus 91.8 100.0 Verified 1 1 1 False True False False False

Additional files