APS3 (YJL024C)


Gene profile

Gene name: APS3
Reference locus (S288C): YJL024C
Gene biotype: protein_coding

Description: AP-3 complex subunit sigma; Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): APL5 (0.999); APL6 (0.999); APM3 (0.996); APL4 (0.968); APM4 (0.945); APM1 (0.916); APM2 (0.89); APL3 (0.834); APL2 (0.81); APL1 (0.81); APS1 (0.8); APS2 (0.782); SFT2 (0.742); VMA21 (0.683); VPS21 (0.682); VMA5 (0.68); VPS45 (0.668); COP1 (0.666); CKS1 (0.655); VPH2 (0.65)

Homologues (species, bitscore): AP3S1 (Homo sapiens, 141.4); Ap3s1 (Mus musculus, 141.4); ap3s2 (Danio rerio, 136.7); ap3s1 (Xenopus tropicalis, 136.3); or (Drosophila melanogaster, 137.9); aps-3 (Caenorhabditis elegans, 133.7); AT3G50860 (Arabidopsis thaliana, 124.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:378887-379548:- gene-YJL024C_AKU4011 rna-NM_001181458.3_AKU4011 cds-NP_012510.3_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:234563-235224:+ gene-YJL024C_BG1 rna-NM_001181458.3_BG1 cds-NP_012510.3_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:393088-393749:- gene-YJL024C_Bruggeman rna-NM_001181458.3_Bruggeman cds-NP_012510.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:397039-397700:- gene-YJL024C_CAT1 rna-NM_001181458.3_CAT1 cds-NP_012510.3_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:390560-391221:- gene-YJL024C_CBS1585 rna-NM_001181458.3_CBS1585 cds-NP_012510.3_CBS1585 99.4 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:408911-409572:- gene-YJL024C_CBS436 rna-NM_001181458.3_CBS436 cds-NP_012510.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:379149-379810:- gene-YJL024C_CBS6412 rna-NM_001181458.3_CBS6412 cds-NP_012510.3_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:381030-381691:- gene-YJL024C_CBS6413 rna-NM_001181458.3_CBS6413 cds-NP_012510.3_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:378352-379013:- gene-YJL024C_CENPK1137D rna-NM_001181458.3_CENPK1137D cds-NP_012510.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:382105-382766:- gene-YJL024C_EthanolRed rna-NM_001181458.3_EthanolRed cds-NP_012510.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:394553-395214:- gene-YJL024C_FaliES1 rna-NM_001181458.3_FaliES1 cds-NP_012510.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000200.1:20217-20878:+ gene-YJL024C_JAY291 rna-NM_001181458.3_JAY291 cds-NP_012510.3_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:393332-393993:- gene-YJL024C_MUCL30387 rna-NM_001181458.3_MUCL30387 cds-NP_012510.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:389474-390135:- gene-YJL024C_MUCL30388 rna-NM_001181458.3_MUCL30388 cds-NP_012510.3_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:383877-384538:- gene-YJL024C_MUCL39482 rna-NM_001181458.3_MUCL39482 cds-NP_012510.3_MUCL39482 99.4 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:389219-389880:- gene-YJL024C_MUCL42920 rna-NM_001181458.3_MUCL42920 cds-NP_012510.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:395910-396571:- gene-YJL024C_NCIM3186 rna-NM_001181458.3_NCIM3186 cds-NP_012510.3_NCIM3186 99.4 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:381825-382486:- gene-YJL024C_NCYC1407 rna-NM_001181458.3_NCYC1407 cds-NP_012510.3_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:393900-394561:- gene-YJL024C_PE2H3 rna-NM_001181458.3_PE2H3 cds-NP_012510.3_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:393546-394207:- gene-YJL024C_PE2H4 rna-NM_001181458.3_PE2H4 cds-NP_012510.3_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:395931-396592:- gene-YJL024C_S288C rna-NM_001181458.3_S288C cds-NP_012510.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:191466-192127:- gene-YJL024C_SA1 rna-NM_001181458.3_SA1 cds-NP_012510.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:388212-388873:- gene-YJL024C_ThermosaccDry rna-NM_001181458.3_ThermosaccDry cds-NP_012510.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:390058-390719:- gene-YJL024C_VR1 rna-NM_001181458.3_VR1 cds-NP_012510.3_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:368882-369543:- gene-YJL024C_ZTW1 rna-NM_001181458.3_ZTW1 cds-NP_012510.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:394129-394788:- gene-YJL024C_Sparadoxus rna-NM_001181458.3_Sparadoxus cds-NP_012510.3_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files