Gene name: APQ12
Reference locus (S288C): YIL040W
Gene biotype: protein_coding
Description: Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism
Top 10 interactors (score): BRR6 (0.948); CHM7 (0.896); POM152 (0.888); SRC1 (0.878); NUP188 (0.829); DBP5 (0.821); POM34 (0.817); NUP2 (0.794); HEH2 (0.771); NUP170 (0.768); YOP1 (0.761); NUP57 (0.751); GLE2 (0.75); NUP157 (0.747); ASM4 (0.747); RTN1 (0.72); NUP116 (0.715); NUP53 (0.712); POM33 (0.696); NUP85 (0.689)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:274551-274967:+ | gene-YIL040W_AKU4011 | rna-NM_001179390.1_AKU4011 | cds-NP_012224.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:135990-136406:+ | gene-YIL040W_BG1 | rna-NM_001179390.1_BG1 | cds-NP_012224.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:280820-281236:+ | gene-YIL040W_Bruggeman | rna-NM_001179390.1_Bruggeman | cds-NP_012224.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:268724-269140:+ | gene-YIL040W_CAT1 | rna-NM_001179390.1_CAT1 | cds-NP_012224.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:274378-274794:+ | gene-YIL040W_CBS1585 | rna-NM_001179390.1_CBS1585 | cds-NP_012224.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:269698-270114:+ | gene-YIL040W_CBS436 | rna-NM_001179390.1_CBS436 | cds-NP_012224.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:270991-271407:+ | gene-YIL040W_CBS6412 | rna-NM_001179390.1_CBS6412 | cds-NP_012224.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:266542-266958:+ | gene-YIL040W_CBS6413 | rna-NM_001179390.1_CBS6413 | cds-NP_012224.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:269636-270052:+ | gene-YIL040W_CENPK1137D | rna-NM_001179390.1_CENPK1137D | cds-NP_012224.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:258465-258881:+ | gene-YIL040W_EthanolRed | rna-NM_001179390.1_EthanolRed | cds-NP_012224.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:276004-276420:+ | gene-YIL040W_FaliES1 | rna-NM_001179390.1_FaliES1 | cds-NP_012224.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:22448-22864:- | gene-YIL040W_JAY291 | rna-NM_001179390.1_JAY291 | cds-NP_012224.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:277670-278086:+ | gene-YIL040W_MUCL30387 | rna-NM_001179390.1_MUCL30387 | cds-NP_012224.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:274273-274689:+ | gene-YIL040W_MUCL30388 | rna-NM_001179390.1_MUCL30388 | cds-NP_012224.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:275219-275635:+ | gene-YIL040W_MUCL39482 | rna-NM_001179390.1_MUCL39482 | cds-NP_012224.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:278363-278779:+ | gene-YIL040W_MUCL42920 | rna-NM_001179390.1_MUCL42920 | cds-NP_012224.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:277723-278139:+ | gene-YIL040W_NCIM3186 | rna-NM_001179390.1_NCIM3186 | cds-NP_012224.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:279492-279908:+ | gene-YIL040W_NCYC1407 | rna-NM_001179390.1_NCYC1407 | cds-NP_012224.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:272752-273168:+ | gene-YIL040W_PE2H3 | rna-NM_001179390.1_PE2H3 | cds-NP_012224.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:267458-267874:+ | gene-YIL040W_PE2H4 | rna-NM_001179390.1_PE2H4 | cds-NP_012224.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:277723-278139:+ | gene-YIL040W_S288C | rna-NM_001179390.1_S288C | cds-NP_012224.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:48019-48435:- | gene-YIL040W_SA1 | rna-NM_001179390.1_SA1 | cds-NP_012224.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:274673-275089:+ | gene-YIL040W_ThermosaccDry | rna-NM_001179390.1_ThermosaccDry | cds-NP_012224.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:271860-272276:+ | gene-YIL040W_VR1 | rna-NM_001179390.1_VR1 | cds-NP_012224.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:248527-248943:+ | gene-YIL040W_ZTW1 | rna-NM_001179390.1_ZTW1 | cds-NP_012224.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:270610-271026:+ | gene-YIL040W_Sparadoxus | rna-NM_001179390.1_Sparadoxus | cds-NP_012224.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |