Gene name: APL2
Reference locus (S288C): YKL135C
Gene biotype: protein_coding
Description: AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): APL4 (0.999); APM1 (0.999); APS1 (0.999); APM4 (0.998); CHC1 (0.997); APS2 (0.997); APL3 (0.996); APM2 (0.996); CLC1 (0.941); VPS1 (0.923); ENT5 (0.903); EDE1 (0.899); END3 (0.897); APL6 (0.875); INP53 (0.87); APL5 (0.861); SEC21 (0.838); HOF1 (0.836); AVL9 (0.836); LAA1 (0.835)
Homologues (species, bitscore): AP2B1 (Homo sapiens, 451.8); Ap2b1 (Mus musculus, 452.2); ap2b1 (Danio rerio, 449.5); ap2b1 (Xenopus tropicalis, 439.9); AP-1-2beta (Drosophila melanogaster, 448.7); apb-1 (Caenorhabditis elegans, 454.1); AT4G23460 (Arabidopsis thaliana, 448.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:173357-175537:- | gene-YKL135C_AKU4011 | rna-NM_001179701.1_AKU4011 | cds-NP_012787.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:150520-152700:- | gene-YKL135C_BG1 | rna-NM_001179701.1_BG1 | cds-NP_012787.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:191019-193199:- | gene-YKL135C_Bruggeman | rna-NM_001179701.1_Bruggeman | cds-NP_012787.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:186341-188521:- | gene-YKL135C_CAT1 | rna-NM_001179701.1_CAT1 | cds-NP_012787.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:185609-187789:- | gene-YKL135C_CBS1585 | rna-NM_001179701.1_CBS1585 | cds-NP_012787.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:184197-186377:- | gene-YKL135C_CBS436 | rna-NM_001179701.1_CBS436 | cds-NP_012787.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:170231-172411:- | gene-YKL135C_CBS6412 | rna-NM_001179701.1_CBS6412 | cds-NP_012787.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:186054-188234:- | gene-YKL135C_CBS6413 | rna-NM_001179701.1_CBS6413 | cds-NP_012787.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:186104-188284:- | gene-YKL135C_CENPK1137D | rna-NM_001179701.1_CENPK1137D | cds-NP_012787.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:184089-186269:- | gene-YKL135C_EthanolRed | rna-NM_001179701.1_EthanolRed | cds-NP_012787.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:184901-187081:- | gene-YKL135C_FaliES1 | rna-NM_001179701.1_FaliES1 | cds-NP_012787.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:7231-9411:- | gene-YKL135C_JAY291 | rna-NM_001179701.1_JAY291 | cds-NP_012787.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:193120-195300:- | gene-YKL135C_MUCL30387 | rna-NM_001179701.1_MUCL30387 | cds-NP_012787.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:187472-189652:- | gene-YKL135C_MUCL30388 | rna-NM_001179701.1_MUCL30388 | cds-NP_012787.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:185387-187567:- | gene-YKL135C_MUCL39482 | rna-NM_001179701.1_MUCL39482 | cds-NP_012787.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:189780-191960:- | gene-YKL135C_MUCL42920 | rna-NM_001179701.1_MUCL42920 | cds-NP_012787.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:186449-188629:- | gene-YKL135C_NCIM3186 | rna-NM_001179701.1_NCIM3186 | cds-NP_012787.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:185577-187757:- | gene-YKL135C_NCYC1407 | rna-NM_001179701.1_NCYC1407 | cds-NP_012787.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:192699-194879:- | gene-YKL135C_PE2H3 | rna-NM_001179701.1_PE2H3 | cds-NP_012787.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:188987-191167:- | gene-YKL135C_PE2H4 | rna-NM_001179701.1_PE2H4 | cds-NP_012787.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:186460-188640:- | gene-YKL135C_S288C | rna-NM_001179701.1_S288C | cds-NP_012787.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:102928-105108:- | gene-YKL135C_SA1 | rna-NM_001179701.1_SA1 | cds-NP_012787.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:185601-187781:- | gene-YKL135C_ThermosaccDry | rna-NM_001179701.1_ThermosaccDry | cds-NP_012787.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:184957-187137:- | gene-YKL135C_VR1 | rna-NM_001179701.1_VR1 | cds-NP_012787.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:184136-186316:- | gene-YKL135C_ZTW1 | rna-NM_001179701.1_ZTW1 | cds-NP_012787.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:200835-203015:- | gene-YKL135C_Sparadoxus | rna-NM_001179701.1_Sparadoxus | cds-NP_012787.1_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |