APJ1 (YNL077W)


Gene profile

Gene name: APJ1
Reference locus (S288C): YNL077W
Gene biotype: protein_coding

Description: J domain-containing protein APJ1; Chaperone with a role in SUMO-mediated protein degradation; member of the DnaJ-like family; conserved across eukaryotes; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; forms nuclear foci upon DNA replication stress

Top 10 interactors (score): SSA4 (0.97); SSA1 (0.967); SSA2 (0.954); BTN2 (0.952); SSA3 (0.948); STI1 (0.942); SSE2 (0.91); SSE1 (0.909); JEM1 (0.886); HSC82 (0.865); HSP82 (0.853); JJJ3 (0.845); JJJ2 (0.845); KAR2 (0.845); ERJ5 (0.843); ZUO1 (0.842); SWA2 (0.839); HSP104 (0.838); CWC23 (0.837); JAC1 (0.834)

Homologues (species, bitscore): DNAJA2 (Homo sapiens, 201.8); Dnaja2 (Mus musculus, 199.9); dnaja2l (Danio rerio, 193.0); dnaja2 (Xenopus tropicalis, 193.0); Droj2 (Drosophila melanogaster, 177.6); dnj-12 (Caenorhabditis elegans, 187.2); J2 (Arabidopsis thaliana, 204.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:475061-476647:+ gene-YNL077W_AKU4011 rna-NM_001182915.1_AKU4011 cds-NP_014322.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:379088-380674:+ gene-YNL077W_BG1 rna-NM_001182915.1_BG1 cds-NP_014322.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:485789-487375:+ gene-YNL077W_Bruggeman rna-NM_001182915.1_Bruggeman cds-NP_014322.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:528785-530371:+ gene-YNL077W_CAT1 rna-NM_001182915.1_CAT1 cds-NP_014322.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:475729-477315:+ gene-YNL077W_CBS1585 rna-NM_001182915.1_CBS1585 cds-NP_014322.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:544143-545729:+ gene-YNL077W_CBS436 rna-NM_001182915.1_CBS436 cds-NP_014322.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:470823-472409:+ gene-YNL077W_CBS6412 rna-NM_001182915.1_CBS6412 cds-NP_014322.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:472140-473726:+ gene-YNL077W_CBS6413 rna-NM_001182915.1_CBS6413 cds-NP_014322.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:475249-476835:+ gene-YNL077W_CENPK1137D rna-NM_001182915.1_CENPK1137D cds-NP_014322.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:477883-479469:+ gene-YNL077W_EthanolRed rna-NM_001182915.1_EthanolRed cds-NP_014322.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:468407-469993:+ gene-YNL077W_FaliES1 rna-NM_001182915.1_FaliES1 cds-NP_014322.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000317.1:3600-5186:- gene-YNL077W_JAY291 rna-NM_001182915.1_JAY291 cds-NP_014322.1_JAY291 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:481953-483539:+ gene-YNL077W_MUCL30387 rna-NM_001182915.1_MUCL30387 cds-NP_014322.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:517350-518936:+ gene-YNL077W_MUCL30388 rna-NM_001182915.1_MUCL30388 cds-NP_014322.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:473132-474718:+ gene-YNL077W_MUCL39482 rna-NM_001182915.1_MUCL39482 cds-NP_014322.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:477060-478646:+ gene-YNL077W_MUCL42920 rna-NM_001182915.1_MUCL42920 cds-NP_014322.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:481360-482946:+ gene-YNL077W_NCIM3186 rna-NM_001182915.1_NCIM3186 cds-NP_014322.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:475182-476768:+ gene-YNL077W_NCYC1407 rna-NM_001182915.1_NCYC1407 cds-NP_014322.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:478418-480004:+ gene-YNL077W_PE2H3 rna-NM_001182915.1_PE2H3 cds-NP_014322.1_PE2H3 99.6 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:473493-475079:+ gene-YNL077W_PE2H4 rna-NM_001182915.1_PE2H4 cds-NP_014322.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:481391-482977:+ gene-YNL077W_S288C rna-NM_001182915.1_S288C cds-NP_014322.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:66344-67930:+ gene-YNL077W_SA1 rna-NM_001182915.1_SA1 cds-NP_014322.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:469283-470869:+ gene-YNL077W_ThermosaccDry rna-NM_001182915.1_ThermosaccDry cds-NP_014322.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:488401-489987:+ gene-YNL077W_VR1 rna-NM_001182915.1_VR1 cds-NP_014322.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:378633-380219:+ gene-YNL077W_ZTW1 rna-NM_001182915.1_ZTW1 cds-NP_014322.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:484796-486385:+ gene-YNL077W_Sparadoxus rna-NM_001182915.1_Sparadoxus cds-NP_014322.1_Sparadoxus 89.7 100.0 Verified 1 1 1 False True False False False

Additional files