Gene name: APE2
Reference locus (S288C): YKL157W
Gene biotype: protein_coding
Description: Aminopeptidase 2, mitochondrial; Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; APE2 has a paralog, AAP1, that arose from the whole genome duplication; Belongs to the peptidase M1 family
Top 10 interactors (score): SEC4 (0.979); APN2 (0.951); LAP3 (0.836); YBR241C (0.803); APE4 (0.801); APE3 (0.79); SLT2 (0.78); APE1 (0.777); SEC26 (0.761); YPR202W (0.75); VPS73 (0.748); BZZ1 (0.666); RHO3 (0.63); RHO1 (0.63); RHO2 (0.63); RHO4 (0.63); ICP55 (0.628); BMH2 (0.604); PRB1 (0.6); FRA1 (0.59)
Homologues (species, bitscore): NPEPPS (Homo sapiens, 522.7); Npepps (Mus musculus, 520.8); npepps (Danio rerio, 543.5); npepps (Xenopus tropicalis, 545.0); Psa (Drosophila melanogaster, 550.4); pam-1 (Caenorhabditis elegans, 475.7); APM1 (Arabidopsis thaliana, 509.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:141884-145125:+ | gene-YKL157W_AKU4011 | rna-NM_001179723.2_AKU4011 | cds-NP_012765.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:118456-121697:+ | gene-YKL157W_BG1 | rna-NM_001179723.2_BG1 | cds-NP_012765.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:159540-162781:+ | gene-YKL157W_Bruggeman | rna-NM_001179723.2_Bruggeman | cds-NP_012765.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:154357-157598:+ | gene-YKL157W_CAT1 | rna-NM_001179723.2_CAT1 | cds-NP_012765.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:154107-157348:+ | gene-YKL157W_CBS1585 | rna-NM_001179723.2_CBS1585 | cds-NP_012765.3_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:152699-155940:+ | gene-YKL157W_CBS436 | rna-NM_001179723.2_CBS436 | cds-NP_012765.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:139133-142374:+ | gene-YKL157W_CBS6412 | rna-NM_001179723.2_CBS6412 | cds-NP_012765.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:154579-157820:+ | gene-YKL157W_CBS6413 | rna-NM_001179723.2_CBS6413 | cds-NP_012765.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:154638-157879:+ | gene-YKL157W_CENPK1137D | rna-NM_001179723.2_CENPK1137D | cds-NP_012765.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:152630-155871:+ | gene-YKL157W_EthanolRed | rna-NM_001179723.2_EthanolRed | cds-NP_012765.3_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:153442-156683:+ | gene-YKL157W_FaliES1 | rna-NM_001179723.2_FaliES1 | cds-NP_012765.3_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000239.2:12407-15648:+ | gene-YKL157W_JAY291 | rna-NM_001179723.2_JAY291 | cds-NP_012765.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:161638-164879:+ | gene-YKL157W_MUCL30387 | rna-NM_001179723.2_MUCL30387 | cds-NP_012765.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:155992-159233:+ | gene-YKL157W_MUCL30388 | rna-NM_001179723.2_MUCL30388 | cds-NP_012765.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:153917-157158:+ | gene-YKL157W_MUCL39482 | rna-NM_001179723.2_MUCL39482 | cds-NP_012765.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:158323-161564:+ | gene-YKL157W_MUCL42920 | rna-NM_001179723.2_MUCL42920 | cds-NP_012765.3_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:154980-158221:+ | gene-YKL157W_NCIM3186 | rna-NM_001179723.2_NCIM3186 | cds-NP_012765.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:154110-157351:+ | gene-YKL157W_NCYC1407 | rna-NM_001179723.2_NCYC1407 | cds-NP_012765.3_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:161183-164424:+ | gene-YKL157W_PE2H3 | rna-NM_001179723.2_PE2H3 | cds-NP_012765.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:157477-160718:+ | gene-YKL157W_PE2H4 | rna-NM_001179723.2_PE2H4 | cds-NP_012765.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:154991-158232:+ | gene-YKL157W_S288C | rna-NM_001179723.2_S288C | cds-NP_012765.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:71408-74649:+ | gene-YKL157W_SA1 | rna-NM_001179723.2_SA1 | cds-NP_012765.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:154142-157383:+ | gene-YKL157W_ThermosaccDry | rna-NM_001179723.2_ThermosaccDry | cds-NP_012765.3_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:152977-156218:+ | gene-YKL157W_VR1 | rna-NM_001179723.2_VR1 | cds-NP_012765.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:152662-155903:+ | gene-YKL157W_ZTW1 | rna-NM_001179723.2_ZTW1 | cds-NP_012765.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:168818-172069:+ | gene-YKL157W_Sparadoxus | rna-NM_001179723.2_Sparadoxus | cds-NP_012765.3_Sparadoxus | 90.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |