Gene name: APE1
Reference locus (S288C): YKL103C
Gene biotype: protein_coding
Description: Metalloaminopeptidase ape1; Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway; protein increases in abundance and relative distribution to cytoplasmic foci increases upon DNA replication stress
Top 10 interactors (score): ATG19 (0.999); AMS1 (0.993); ATG8 (0.988); ATG11 (0.982); ICP55 (0.971); ATG9 (0.943); TFS1 (0.943); FRA1 (0.915); ATG13 (0.878); ATG1 (0.871); YJL068C (0.87); GAD1 (0.869); PEP4 (0.868); ATG34 (0.835); ADO1 (0.828); PRM15 (0.825); GLK1 (0.823); ADE12 (0.822); RKI1 (0.821); ADH4 (0.819)
Homologues (species, bitscore): DNPEP (Homo sapiens, 228.0); Dnpep (Mus musculus, 235.3); dnpep (Danio rerio, 242.3); dnpep (Xenopus tropicalis, 227.6); dnpp-1 (Caenorhabditis elegans, 183.0); AT5G60160 (Arabidopsis thaliana, 236.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:232689-234233:- | gene-YKL103C_AKU4011 | rna-NM_001179669.1_AKU4011 | cds-NP_012819.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:209807-211351:- | gene-YKL103C_BG1 | rna-NM_001179669.1_BG1 | cds-NP_012819.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:250864-252408:- | gene-YKL103C_Bruggeman | rna-NM_001179669.1_Bruggeman | cds-NP_012819.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:245655-247199:- | gene-YKL103C_CAT1 | rna-NM_001179669.1_CAT1 | cds-NP_012819.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:244928-246472:- | gene-YKL103C_CBS1585 | rna-NM_001179669.1_CBS1585 | cds-NP_012819.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:243520-245064:- | gene-YKL103C_CBS436 | rna-NM_001179669.1_CBS436 | cds-NP_012819.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:229560-231104:- | gene-YKL103C_CBS6412 | rna-NM_001179669.1_CBS6412 | cds-NP_012819.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:245384-246928:- | gene-YKL103C_CBS6413 | rna-NM_001179669.1_CBS6413 | cds-NP_012819.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:245779-247323:- | gene-YKL103C_CENPK1137D | rna-NM_001179669.1_CENPK1137D | cds-NP_012819.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:243380-244924:- | gene-YKL103C_EthanolRed | rna-NM_001179669.1_EthanolRed | cds-NP_012819.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:244193-245737:- | gene-YKL103C_FaliES1 | rna-NM_001179669.1_FaliES1 | cds-NP_012819.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:66520-68064:- | gene-YKL103C_JAY291 | rna-NM_001179669.1_JAY291 | cds-NP_012819.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:252657-254201:- | gene-YKL103C_MUCL30387 | rna-NM_001179669.1_MUCL30387 | cds-NP_012819.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:247056-248600:- | gene-YKL103C_MUCL30388 | rna-NM_001179669.1_MUCL30388 | cds-NP_012819.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:244716-246260:- | gene-YKL103C_MUCL39482 | rna-NM_001179669.1_MUCL39482 | cds-NP_012819.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:249101-250645:- | gene-YKL103C_MUCL42920 | rna-NM_001179669.1_MUCL42920 | cds-NP_012819.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:246127-247671:- | gene-YKL103C_NCIM3186 | rna-NM_001179669.1_NCIM3186 | cds-NP_012819.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:244907-246451:- | gene-YKL103C_NCYC1407 | rna-NM_001179669.1_NCYC1407 | cds-NP_012819.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:251995-253539:- | gene-YKL103C_PE2H3 | rna-NM_001179669.1_PE2H3 | cds-NP_012819.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:248281-249825:- | gene-YKL103C_PE2H4 | rna-NM_001179669.1_PE2H4 | cds-NP_012819.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:246138-247682:- | gene-YKL103C_S288C | rna-NM_001179669.1_S288C | cds-NP_012819.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:162243-163787:- | gene-YKL103C_SA1 | rna-NM_001179669.1_SA1 | cds-NP_012819.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:244898-246442:- | gene-YKL103C_ThermosaccDry | rna-NM_001179669.1_ThermosaccDry | cds-NP_012819.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:244255-245799:- | gene-YKL103C_VR1 | rna-NM_001179669.1_VR1 | cds-NP_012819.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:243461-245005:- | gene-YKL103C_ZTW1 | rna-NM_001179669.1_ZTW1 | cds-NP_012819.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:260425-261969:- | gene-YKL103C_Sparadoxus | rna-NM_001179669.1_Sparadoxus | cds-NP_012819.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |